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MRK-409 (MK-0343), a GABAA receptor subtype-selective partial agonist, is a non-sedating anxiolytic in preclinical species but causes sedation in humans

Journal of psychopharmacology (Oxford), 2011-03, Vol.25 (3), p.314-328

2011

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Synthesis, characterization, and first successful monkey imaging studies of metabotropic glutamate receptor subtype 5 (mGluR5) PET radiotracers

Synapse (New York, N.Y.), 2005-06, Vol.56 (4), p.205-216

2005

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Human positron emission tomography studies of brain neurokinin 1 receptor occupancy by aprepitant

Biological psychiatry (1969), 2004-05, Vol.55 (10), p.1007-1012

2004

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MRK-409 (MK-0343), a GABA A receptor subtype-selective partial agonist, is a non-sedating anxiolytic in preclinical species but causes sedation in humans

Journal of psychopharmacology (Oxford), 2011-03, Vol.25 (3), p.314-328

2011

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Apert Syndrome Mutations in Fibroblast Growth Factor Receptor 2 Exhibit increased Affinity for FGF Ligand

Human molecular genetics, 1998-09, Vol.7 (9), p.1475-1483

1998

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Preclinical and clinical pharmacology of TPA023B, a GABAA receptor α2/α3 subtype-selective partial agonist

Journal of psychopharmacology (Oxford), 2011-03, Vol.25 (3), p.329-344

2011

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Association of the Signaling Adaptor FRS2 with Fibroblast Growth Factor Receptor 1 (Fgfr1) Is Mediated by Alternative Splicing of the Juxtamembrane Domain

The Journal of biological chemistry, 2002-02, Vol.277 (6), p.4018-4023

2002

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Early posterior neural tissue is induced by FGF in the chick embryo

Development (Cambridge), 1998-02, Vol.125 (3), p.473-484

1998

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A remote-controlled high pressure reactor for radiotracer synthesis with [ 11C]carbon monoxide

Nuclear medicine and biology, 2002-11, Vol.29 (8), p.845-848

2002

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Screening cascade and development of potential Positron Emission Tomography radiotracers for mGluR5: in vitro and in vivo characterization

Molecular imaging and biology, 2005-07, Vol.7 (4), p.314-323

2005

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MRK-409 (MK-0343), a GABA^sub A^ receptor subtype-selective partial agonist, is a non-sedating anxiolytic in preclinical species but causes sedation in humans

Journal of psychopharmacology (Oxford), 2011-03, Vol.25 (3), p.314

2011

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An improved synthesis of substituted [11C]toluenes via Suzuki coupling with [11C]methyl iodide

Journal of labelled compounds & radiopharmaceuticals, 2005-08, Vol.48 (9), p.629-634

2005

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Non-invasive radiotracer imaging as a tool for drug development

Current pharmaceutical design, 2000-07, Vol.6 (10), p.973-989

2000

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Preclinical and clinical pharmacology of TPA023B, a GABA A receptor α2/α3 subtype-selective partial agonist

Journal of psychopharmacology (Oxford), 2011-03, Vol.25 (3), p.329-344

2011

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Preclinical and clinical pharmacology of TPA023B, a GABA^sub A^ receptor [alpha]2/[alpha]3 subtype-selective partial agonist

Journal of psychopharmacology (Oxford), 2011-03, Vol.25 (3), p.329

2011

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Synthesis and characterization of a potent, selective, radiolabeled substance-P antagonist for NK1 receptor quantitation: ([18F]SPA-RQ)

Molecular imaging and biology, 2004-11, Vol.6 (6), p.373-384

2004

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Positron emission tomography neuroreceptor imaging as a tool in drug discovery, research and development

Current opinion in chemical biology, 1999-08, Vol.3 (4), p.388-394

1999

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The synthesis of a benzamidine-containing NR2B-selective NMDA receptor ligand labelled with tritium or fluorine-18

Journal of labelled compounds & radiopharmaceuticals, 2005-01, Vol.48 (1), p.1-10

2005

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Histamine H3 inverse agonist PET tracers labelled with carbon-11 or fluorine-18

NeuroImage (Orlando, Fla.), 2008, Vol.41, p.T22-T22

2008

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In Vivo Labeling of Endothelin Receptors with [11C]L-753,037: Studies in Mice and a Dog

The Journal of nuclear medicine (1978), 2001-08, Vol.42 (8), p.1274-1280

2001

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The synthesis of tritium labelled neurokinin-1 receptor ligands

Journal of labelled compounds & radiopharmaceuticals, 2004-02, Vol.47 (2), p.99-106

2004

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Open complex formation during transcription initiation at the Escherichia coli galP1 promoter: the role of the RNA polymerase alpha subunit at promoters lacking an UP-element

Nucleic acids research, 1999-05, Vol.27 (9), p.2051

1999

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Conserved Use of a Non-Canonical 5′ Splice Site (/GA) in Alternative Splicing by Fibroblast Growth Factor Receptors 1, 2 and 3

Human molecular genetics, 1998-04, Vol.7 (4), p.685-691

1998

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Structure and morphology of phthalocyanine films grown in electrical fields by vapor deposition

Journal of crystal growth, 2000-04, Vol.211 (1), p.308-312

2000

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Temperature-dependence of open-complex formation at two Escherichia coli promoters with extended -10 sequences

Biochemical journal, 1996-07, Vol.317 ( Pt 1) (1), p.305-311

1996

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MRK-409 (MK-0343), a GABAA receptor subtype-selective partial agonist, is a non-sedating anxiolytic in preclinical species but causes sedation in humans

Synthesis, characterization, and first successful monkey imaging studies of metabotropic glutamate receptor subtype 5 (mGluR5) PET radiotracers

Human positron emission tomography studies of brain neurokinin 1 receptor occupancy by aprepitant

MRK-409 (MK-0343), a GABA A receptor subtype-selective partial agonist, is a non-sedating anxiolytic in preclinical species but causes sedation in humans

Apert Syndrome Mutations in Fibroblast Growth Factor Receptor 2 Exhibit increased Affinity for FGF Ligand

Preclinical and clinical pharmacology of TPA023B, a GABAA receptor α2/α3 subtype-selective partial agonist

Association of the Signaling Adaptor FRS2 with Fibroblast Growth Factor Receptor 1 (Fgfr1) Is Mediated by Alternative Splicing of the Juxtamembrane Domain

Early posterior neural tissue is induced by FGF in the chick embryo

A remote-controlled high pressure reactor for radiotracer synthesis with [ 11C]carbon monoxide

Screening cascade and development of potential Positron Emission Tomography radiotracers for mGluR5: in vitro and in vivo characterization

MRK-409 (MK-0343), a GABA^sub A^ receptor subtype-selective partial agonist, is a non-sedating anxiolytic in preclinical species but causes sedation in humans

An improved synthesis of substituted [11C]toluenes via Suzuki coupling with [11C]methyl iodide

Non-invasive radiotracer imaging as a tool for drug development

Preclinical and clinical pharmacology of TPA023B, a GABA A receptor α2/α3 subtype-selective partial agonist

Preclinical and clinical pharmacology of TPA023B, a GABA^sub A^ receptor [alpha]2/[alpha]3 subtype-selective partial agonist

Synthesis and characterization of a potent, selective, radiolabeled substance-P antagonist for NK1 receptor quantitation: ([18F]SPA-RQ)

Positron emission tomography neuroreceptor imaging as a tool in drug discovery, research and development

The synthesis of a benzamidine-containing NR2B-selective NMDA receptor ligand labelled with tritium or fluorine-18

Histamine H3 inverse agonist PET tracers labelled with carbon-11 or fluorine-18

In Vivo Labeling of Endothelin Receptors with [11C]L-753,037: Studies in Mice and a Dog

The synthesis of tritium labelled neurokinin-1 receptor ligands

Open complex formation during transcription initiation at the Escherichia coli galP1 promoter: the role of the RNA polymerase alpha subunit at promoters lacking an UP-element

Conserved Use of a Non-Canonical 5′ Splice Site (/GA) in Alternative Splicing by Fibroblast Growth Factor Receptors 1, 2 and 3

Structure and morphology of phthalocyanine films grown in electrical fields by vapor deposition

Temperature-dependence of open-complex formation at two Escherichia coli promoters with extended -10 sequences

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