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Contributions of human tumor xenografts to anticancer drug development

Cancer research (Chicago, Ill.), 2006-04, Vol.66 (7), p.3351-3354

2006

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Exploring the Structural Requirements for Inhibition of the Ubiquitin E3 Ligase Breast Cancer Associated Protein 2 (BCA2) as a Treatment for Breast Cancer

Journal of medicinal chemistry, 2010-04, Vol.53 (7), p.2757-2765

2010

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Phase I Study of Vorinostat in Combination with Bortezomib for Relapsed and Refractory Multiple Myeloma

Clinical cancer research, 2009-08, Vol.15 (16), p.5250-5257

2009

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Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of the Combination of Sorafenib and Tanespimycin

Clinical cancer research, 2010-07, Vol.16 (14), p.3795-3804

2010

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Essential roles of IGFBP-3 and IGFBP-rP1 in breast cancer

European journal of cancer (1990), 2005-07, Vol.41 (11), p.1515-1527

2005

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In vivo antitumor efficacy of 17-DMAG (17-dimethylaminoethylamino-17-demethoxygeldanamycin hydrochloride), a water-soluble geldanamycin derivative

Cancer chemotherapy and pharmacology, 2005-08, Vol.56 (2), p.115-125

2005

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Comparison of 17-dimethylaminoethylamino-17-demethoxy-geldanamycin (17DMAG) and 17-allylamino-17-demethoxygeldanamycin (17AAG) in vitro: effects on Hsp90 and client proteins in melanoma models

Cancer chemotherapy and pharmacology, 2005-08, Vol.56 (2), p.126-137

2005

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HDM2 antagonist MI-219 (spiro-oxindole), but not Nutlin-3 (cis-imidazoline), regulates p53 through enhanced HDM2 autoubiquitination and degradation in human malignant B-cell lymphomas

Journal of hematology and oncology, 2012-09, Vol.5 (1), p.57-57, Article 57

2012

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EBP1, an ErbB3-binding protein, is decreased in prostate cancer and implicated in hormone resistance

Molecular cancer therapeutics, 2008-10, Vol.7 (10), p.3176-3186

2008

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Editor's Note: Antiangiogenic Properties of 17-(Dimethylaminoethylamino)-17-Demethoxygeldanamycin: An Orally Bioavailable Heat Shock Protein 90 Modulator

Clinical cancer research, 2024-05, Vol.30 (9), p.1996-1996

2024

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KML001 Cytotoxic Activity Is Associated with Its Binding to Telomeric Sequences and Telomere Erosion in Prostate Cancer Cells

Clinical cancer research, 2008-07, Vol.14 (14), p.4593-4602

2008

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Therapeutic Implications of Leukemic Stem Cell Pathways

Clinical cancer research, 2007-11, Vol.13 (22), p.6549-6554

2007

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Pharmacodynamics of the G-Quadruplex-Stabilizing Telomerase Inhibitor 3,11-Difluoro-6,8,13-trimethyl-8H-quino[4,3,2-kl]acridinium methosulfate (RHPS4) in Vitro: Activity in Human Tumor Cells Correlates with Telomere Length and Can Be Enhanced, or Antagonized, with Cytotoxic Agents

Molecular pharmacology, 2005-12, Vol.68 (6), p.1551-1558

2005

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Phospho-p70S6K/p85S6K and cdc2/cdk1 Are Novel Targets for Diffuse Large B-Cell Lymphoma Combination Therapy

Clinical cancer research, 2009-03, Vol.15 (5), p.1708-1720

2009

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Aminoflavone, a Ligand of the Aryl Hydrocarbon Receptor, Inhibits HIF-1α Expression in an AhR-Independent Fashion

Cancer research (Chicago, Ill.), 2010-09, Vol.70 (17), p.6837-6848

2010

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The G-quadruplex-interactive molecule BRACO-19 inhibits tumor growth, consistent with telomere targeting and interference with telomerase function

Cancer research (Chicago, Ill.), 2005-02, Vol.65 (4), p.1489-1496

2005

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The ubiquitin-mediated protein degradation pathway in cancer: therapeutic implications

European journal of cancer (1990), 2004-10, Vol.40 (15), p.2217-2229

2004

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Validation of tumour models for use in anticancer nanomedicine evaluation: the EPR effect and cathepsin B-mediated drug release rate

Cancer chemotherapy and pharmacology, 2013-08, Vol.72 (2), p.417-427

2013

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Characterisation of breast cancer cell lines and establishment of a novel isogenic subclone to study migration, invasion and tumourigenicity

Clinical & experimental metastasis, 2008-09, Vol.25 (5), p.549-557

2008

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Highlights in experimental therapeutics

Cancer letters, 2007-01, Vol.245 (1), p.11-21

Burger, Angelika M

2007

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Antitumor Activity of Bis-indole Derivatives

Journal of medicinal chemistry, 2008-08, Vol.51 (15), p.4563-4570

2008

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Tissue Microarrays of Human Tumor Xenografts: Characterization of Proteins Involved in Migration and Angiogenesis for Applications in the Development of Targeted Anticancer Agents

Cancer genomics & proteomics, 2008-09, Vol.5 (5), p.263-273

2008

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Targetable HPMA Copolymer-Aminohexylgeldanamycin Conjugates for Prostate Cancer Therapy

Pharmaceutical research, 2009-06, Vol.26 (6), p.1407-1418

2009

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Phase II Study of Pemetrexed and Cisplatin, with Chest Radiotherapy Followed by Docetaxel in Patients with Stage III Non-small Cell Lung Cancer

Journal of thoracic oncology, 2011-05, Vol.6 (5), p.927-933

2011

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A Role for OCT4 in Tumor Initiation of Drug-Resistant Prostate Cancer Cells

Genes & cancer, 2010-09, Vol.1 (9), p.908-916

2010

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Contributions of human tumor xenografts to anticancer drug development

Exploring the Structural Requirements for Inhibition of the Ubiquitin E3 Ligase Breast Cancer Associated Protein 2 (BCA2) as a Treatment for Breast Cancer

Phase I Study of Vorinostat in Combination with Bortezomib for Relapsed and Refractory Multiple Myeloma

Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of the Combination of Sorafenib and Tanespimycin

Essential roles of IGFBP-3 and IGFBP-rP1 in breast cancer

In vivo antitumor efficacy of 17-DMAG (17-dimethylaminoethylamino-17-demethoxygeldanamycin hydrochloride), a water-soluble geldanamycin derivative

Comparison of 17-dimethylaminoethylamino-17-demethoxy-geldanamycin (17DMAG) and 17-allylamino-17-demethoxygeldanamycin (17AAG) in vitro: effects on Hsp90 and client proteins in melanoma models

HDM2 antagonist MI-219 (spiro-oxindole), but not Nutlin-3 (cis-imidazoline), regulates p53 through enhanced HDM2 autoubiquitination and degradation in human malignant B-cell lymphomas

EBP1, an ErbB3-binding protein, is decreased in prostate cancer and implicated in hormone resistance

Editor's Note: Antiangiogenic Properties of 17-(Dimethylaminoethylamino)-17-Demethoxygeldanamycin: An Orally Bioavailable Heat Shock Protein 90 Modulator

KML001 Cytotoxic Activity Is Associated with Its Binding to Telomeric Sequences and Telomere Erosion in Prostate Cancer Cells

Therapeutic Implications of Leukemic Stem Cell Pathways

Pharmacodynamics of the G-Quadruplex-Stabilizing Telomerase Inhibitor 3,11-Difluoro-6,8,13-trimethyl-8H-quino[4,3,2-kl]acridinium methosulfate (RHPS4) in Vitro: Activity in Human Tumor Cells Correlates with Telomere Length and Can Be Enhanced, or Antagonized, with Cytotoxic Agents

Phospho-p70S6K/p85S6K and cdc2/cdk1 Are Novel Targets for Diffuse Large B-Cell Lymphoma Combination Therapy

Aminoflavone, a Ligand of the Aryl Hydrocarbon Receptor, Inhibits HIF-1α Expression in an AhR-Independent Fashion

The G-quadruplex-interactive molecule BRACO-19 inhibits tumor growth, consistent with telomere targeting and interference with telomerase function

The ubiquitin-mediated protein degradation pathway in cancer: therapeutic implications

Validation of tumour models for use in anticancer nanomedicine evaluation: the EPR effect and cathepsin B-mediated drug release rate

Characterisation of breast cancer cell lines and establishment of a novel isogenic subclone to study migration, invasion and tumourigenicity

Highlights in experimental therapeutics

Antitumor Activity of Bis-indole Derivatives

Tissue Microarrays of Human Tumor Xenografts: Characterization of Proteins Involved in Migration and Angiogenesis for Applications in the Development of Targeted Anticancer Agents

Targetable HPMA Copolymer-Aminohexylgeldanamycin Conjugates for Prostate Cancer Therapy

Phase II Study of Pemetrexed and Cisplatin, with Chest Radiotherapy Followed by Docetaxel in Patients with Stage III Non-small Cell Lung Cancer

A Role for OCT4 in Tumor Initiation of Drug-Resistant Prostate Cancer Cells

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