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Fundamental Molecules and Mechanisms for Forming and Maintaining Neuromuscular Synapses

International journal of molecular sciences, 2018-02, Vol.19 (2), p.490

2018

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FoxO3 Controls Autophagy in Skeletal Muscle In Vivo

Cell metabolism, 2007-12, Vol.6 (6), p.458-471

2007

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Mechanism of disease and therapeutic rescue of Dok7 congenital myasthenia

Nature (London), 2021-07, Vol.595 (7867), p.404-408

2021

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MuSK IgG4 autoantibodies cause myasthenia gravis by inhibiting binding between MuSK and Lrp4

Proceedings of the National Academy of Sciences - PNAS, 2013-12, Vol.110 (51), p.20783-20788

2013

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Agrin Binds to the N-terminal Region of Lrp4 Protein and Stimulates Association between Lrp4 and the First Immunoglobulin-like Domain in Muscle-specific Kinase (MuSK)

The Journal of biological chemistry, 2011-11, Vol.286 (47), p.40624-40630

2011

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Increasing MuSK Activity Delays Denervation and Improves Motor Function in ALS Mice

Cell reports (Cambridge), 2012-09, Vol.2 (3), p.497-502

2012

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Preserving neuromuscular synapses in ALS by stimulating MuSK with a therapeutic agonist antibody

eLife, 2018-02, Vol.7

2018

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Affinity maturation is required for pathogenic monovalent IgG4 autoantibody development in myasthenia gravis

The Journal of experimental medicine, 2020-12, Vol.217 (12)

2020

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Dok-7 regulates neuromuscular synapse formation by recruiting Crk and Crk-L

Genes & development, 2010-11, Vol.24 (21), p.2451-2461

2010

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The Cytoplasmic Adaptor Protein Dok7 Activates the Receptor Tyrosine Kinase MuSK via Dimerization

Molecular cell, 2010-07, Vol.39 (1), p.100-109

2010

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Diverging roles for Lrp4 and Wnt signaling in neuromuscular synapse development during evolution

Genes & development, 2016-05, Vol.30 (9), p.1058-1069

2016

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Lrp4 is a retrograde signal for presynaptic differentiation at neuromuscular synapses

Nature (London), 2012-09, Vol.489 (7416), p.438-442

2012

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Like-acetylglucosaminyltransferase (LARGE)-dependent modification of dystroglycan at Thr-317/319 is required for laminin binding and arenavirus infection

Proceedings of the National Academy of Sciences - PNAS, 2011-10, Vol.108 (42), p.17426-17431

2011

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Synaptic plasticity and cognitive function are disrupted in the absence of Lrp4

eLife, 2014-11, Vol.3, p.e04287-e04287

2014

Volltextzugriff (PDF)

The extracellular region of Lrp4 is sufficient to mediate neuromuscular synapse formation

Developmental dynamics, 2011-12, Vol.240 (12), p.2626-2633

2011

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Abelson tyrosine-protein kinase 2 regulates myoblast proliferation and controls muscle fiber length

eLife, 2017-12, Vol.6

2017

Volltextzugriff (PDF)

Rescuing Z⁺ agrin splicing in Nova null mice restores synapse formation and unmasks a physiologic defect in motor neuron firing

Proceedings of the National Academy of Sciences - PNAS, 2009-03, Vol.106 (9), p.3513-3518

2009

Volltextzugriff (PDF)

A novel role for MuSK and non-canonical Wnt signaling during segmental neural crest cell migration

Development (Cambridge), 2011-08, Vol.138 (15), p.3287-3296

2011

Volltextzugriff (PDF)

Runx1 prevents wasting, myofibrillar disorganization, and autophagy of skeletal muscle

Genes & development, 2005-07, Vol.19 (14), p.1715-1722

2005

Volltextzugriff (PDF)

Crystal Structure of the Frizzled-Like Cysteine-Rich Domain of the Receptor Tyrosine Kinase MuSK

Journal of molecular biology, 2009-10, Vol.393 (1), p.1-9

2009

Volltextzugriff (PDF)

Increased Mitochondrial Mass in Mitochondrial Myopathy Mice

Proceedings of the National Academy of Sciences - PNAS, 2002-11, Vol.99 (23), p.15066-15071

2002

Volltextzugriff (PDF)

The critical role of agrin in the hematopoietic stem cell niche

Blood, 2011-09, Vol.118 (10), p.2733-2742

2011

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MuSK controls where motor axons grow and form synapses

Nature neuroscience, 2008-01, Vol.11 (1), p.19-27

2008

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Building, Breaking, and Repairing Neuromuscular Synapses

Cold Spring Harbor perspectives in biology, 2024-05, Vol.16 (5)

2024

Volltextzugriff (PDF)

SnapShot: Neuromuscular Junction

Cell, 2011-03, Vol.144 (5), p.826-826.e1

Burden, Steven J.

2011

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Fundamental Molecules and Mechanisms for Forming and Maintaining Neuromuscular Synapses

FoxO3 Controls Autophagy in Skeletal Muscle In Vivo

Mechanism of disease and therapeutic rescue of Dok7 congenital myasthenia

MuSK IgG4 autoantibodies cause myasthenia gravis by inhibiting binding between MuSK and Lrp4

Agrin Binds to the N-terminal Region of Lrp4 Protein and Stimulates Association between Lrp4 and the First Immunoglobulin-like Domain in Muscle-specific Kinase (MuSK)

Increasing MuSK Activity Delays Denervation and Improves Motor Function in ALS Mice

Preserving neuromuscular synapses in ALS by stimulating MuSK with a therapeutic agonist antibody

Affinity maturation is required for pathogenic monovalent IgG4 autoantibody development in myasthenia gravis

Dok-7 regulates neuromuscular synapse formation by recruiting Crk and Crk-L

The Cytoplasmic Adaptor Protein Dok7 Activates the Receptor Tyrosine Kinase MuSK via Dimerization

Diverging roles for Lrp4 and Wnt signaling in neuromuscular synapse development during evolution

Lrp4 is a retrograde signal for presynaptic differentiation at neuromuscular synapses

Like-acetylglucosaminyltransferase (LARGE)-dependent modification of dystroglycan at Thr-317/319 is required for laminin binding and arenavirus infection

Synaptic plasticity and cognitive function are disrupted in the absence of Lrp4

The extracellular region of Lrp4 is sufficient to mediate neuromuscular synapse formation

Abelson tyrosine-protein kinase 2 regulates myoblast proliferation and controls muscle fiber length

Rescuing Z⁺ agrin splicing in Nova null mice restores synapse formation and unmasks a physiologic defect in motor neuron firing

A novel role for MuSK and non-canonical Wnt signaling during segmental neural crest cell migration

Runx1 prevents wasting, myofibrillar disorganization, and autophagy of skeletal muscle

Crystal Structure of the Frizzled-Like Cysteine-Rich Domain of the Receptor Tyrosine Kinase MuSK

Increased Mitochondrial Mass in Mitochondrial Myopathy Mice

The critical role of agrin in the hematopoietic stem cell niche

MuSK controls where motor axons grow and form synapses

Building, Breaking, and Repairing Neuromuscular Synapses

SnapShot: Neuromuscular Junction

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