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Latest developments in MUC1 immunotherapy

Biochemical Society transactions, 2018-06, Vol.46 (3), p.659-668

2018

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The mucin MUC1 modulates the tumor immunological microenvironment through engagement of the lectin Siglec-9

Nature immunology, 2016-11, Vol.17 (11), p.1273-1281

2016

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O-linked mucin-type glycosylation in breast cancer

Biochemical Society transactions, 2018-08, Vol.46 (4), p.779-788

2018

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The Breast Cancer-Associated Glycoforms of MUC1, MUC1-Tn and sialyl-Tn, Are Expressed in COSMC Wild-Type Cells and Bind the C-Type Lectin MGL

PloS one, 2015-05, Vol.10 (5), p.e0125994-e0125994

2015

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Histone Methylases and Demethylases Regulating Antagonistic Methyl Marks: Changes Occurring in Cancer

Cells (Basel, Switzerland), 2022-03, Vol.11 (7), p.1113

2022

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Mammosphere culture of metastatic breast cancer cells enriches for tumorigenic breast cancer cells

Breast cancer research : BCR, 2008-01, Vol.10 (3), p.R52-R52, Article R52

2008

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Selectin Ligand Sialyl-Lewis x Antigen Drives Metastasis of Hormone-Dependent Breast Cancers

Cancer research (Chicago, Ill.), 2011-12, Vol.71 (24), p.7683-7693

2011

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A mucin degrader for cancer therapy

Nature biotechnology, 2024-04, Vol.42 (4), p.572-573

2024

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Apoptosis in the Pancreatic Cancer Tumor Microenvironment—The Double-Edged Sword of Cancer-Associated Fibroblasts

Cells (Basel, Switzerland), 2021-07, Vol.10 (7), p.1653

2021

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Identification of new cancer biomarkers based on aberrant mucin glycoforms by in situ proximity ligation

Journal of cellular and molecular medicine, 2012-07, Vol.16 (7), p.1474-1484

2012

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Autoantibodies to aberrantly glycosylated MUC1 in early stage breast cancer are associated with a better prognosis

Breast cancer research : BCR, 2011-03, Vol.13 (2), p.R25-R25, Article R25

2011

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Characterizing the glycome of the mammalian immune system

Immunology and cell biology, 2008-10, Vol.86 (7), p.564-573

2008

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Retargeting of Human T Cells to Tumor-Associated MUC1: The Evolution of a Chimeric Antigen Receptor

The Journal of immunology (1950), 2008-04, Vol.180 (7), p.4901-4909

2008

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PLU-1/JARID1B/KDM5B is required for embryonic survival and contributes to cell proliferation in the mammary gland and in ER+ breast cancer cells

International journal of oncology, 2011-05, Vol.38 (5), p.1267-1277

2011

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Recombinant Tumor-Associated MUC1 Glycoprotein Impairs the Differentiation and Function of Dendritic Cells

The Journal of immunology (1950), 2005-06, Vol.174 (12), p.7764-7772

2005

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Targeting DNGR‐1 (CLEC9A) with antibody/MUC1 peptide conjugates as a vaccine for carcinomas

European journal of immunology, 2014-07, Vol.44 (7), p.1947-1955

2014

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O-linked mucin-type glycosylation regulates the transcriptional programme downstream of EGFR

Glycobiology (Oxford), 2021-04, Vol.31 (3), p.200-210

2021

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LYVE-1+ macrophages form a collaborative CCR5-dependent perivascular niche that influences chemotherapy responses in murine breast cancer

Developmental cell, 2023-09, Vol.58 (17), p.1548-1561.e10

2023

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Repurposing Tin Mesoporphyrin as an Immune Checkpoint Inhibitor Shows Therapeutic Efficacy in Preclinical Models of Cancer

Clinical cancer research, 2018-04, Vol.24 (7), p.1617-1628

2018

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Two E-selectin ligands, BST-2 and LGALS3BP, predict metastasis and poor survival of ER-negative breast cancer

International journal of oncology, 2016-07, Vol.49 (1), p.265-275

2016

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MUC1 immunotherapy

Immunotherapy, 2010-05, Vol.2 (3), p.305-327

2010

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Cyclooxygenase-2 Enzyme Induces the Expression of the α-2,3-Sialyltransferase-3 (ST3Gal-I) in Breast Cancer

The Journal of biological chemistry, 2012-12, Vol.287 (53), p.44490-44497

2012

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Cyclooxygenase-2 enzyme induces the expression of the α-2,3-sialyltransferase-3 (ST3Gal-I) in breast cancer

The Journal of biological chemistry, 2012-12, Vol.287 (53), p.44490-44497

2012

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Cancer-associated hypersialylated MUC1 drives the differentiation of human monocytes into macrophages with a pathogenic phenotype

Communications biology, 2020-11, Vol.3 (1), p.644-644, Article 644

2020

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Transforming growth factor-β1 is constitutively secreted by chinese hamster ovary cells and is functional in human cells

Biotechnology and bioengineering, 2011-11, Vol.108 (11), p.2759-2764

2011

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Latest developments in MUC1 immunotherapy

The mucin MUC1 modulates the tumor immunological microenvironment through engagement of the lectin Siglec-9

O-linked mucin-type glycosylation in breast cancer

The Breast Cancer-Associated Glycoforms of MUC1, MUC1-Tn and sialyl-Tn, Are Expressed in COSMC Wild-Type Cells and Bind the C-Type Lectin MGL

Histone Methylases and Demethylases Regulating Antagonistic Methyl Marks: Changes Occurring in Cancer

Mammosphere culture of metastatic breast cancer cells enriches for tumorigenic breast cancer cells

Selectin Ligand Sialyl-Lewis x Antigen Drives Metastasis of Hormone-Dependent Breast Cancers

A mucin degrader for cancer therapy

Apoptosis in the Pancreatic Cancer Tumor Microenvironment—The Double-Edged Sword of Cancer-Associated Fibroblasts

Identification of new cancer biomarkers based on aberrant mucin glycoforms by in situ proximity ligation

Autoantibodies to aberrantly glycosylated MUC1 in early stage breast cancer are associated with a better prognosis

Characterizing the glycome of the mammalian immune system

Retargeting of Human T Cells to Tumor-Associated MUC1: The Evolution of a Chimeric Antigen Receptor

PLU-1/JARID1B/KDM5B is required for embryonic survival and contributes to cell proliferation in the mammary gland and in ER+ breast cancer cells

Recombinant Tumor-Associated MUC1 Glycoprotein Impairs the Differentiation and Function of Dendritic Cells

Targeting DNGR‐1 (CLEC9A) with antibody/MUC1 peptide conjugates as a vaccine for carcinomas

O-linked mucin-type glycosylation regulates the transcriptional programme downstream of EGFR

LYVE-1+ macrophages form a collaborative CCR5-dependent perivascular niche that influences chemotherapy responses in murine breast cancer

Repurposing Tin Mesoporphyrin as an Immune Checkpoint Inhibitor Shows Therapeutic Efficacy in Preclinical Models of Cancer

Two E-selectin ligands, BST-2 and LGALS3BP, predict metastasis and poor survival of ER-negative breast cancer

MUC1 immunotherapy

Cyclooxygenase-2 Enzyme Induces the Expression of the α-2,3-Sialyltransferase-3 (ST3Gal-I) in Breast Cancer

Cyclooxygenase-2 enzyme induces the expression of the α-2,3-sialyltransferase-3 (ST3Gal-I) in breast cancer

Cancer-associated hypersialylated MUC1 drives the differentiation of human monocytes into macrophages with a pathogenic phenotype

Transforming growth factor-β1 is constitutively secreted by chinese hamster ovary cells and is functional in human cells

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