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The Therapeutic Potential of Vitamins B1, B3 and B6 in Charcot-Marie-Tooth Disease with the Compromised Status of Vitamin-Dependent Processes

Biology (Basel, Switzerland), 2023-06, Vol.12 (7), p.897

Bunik, Victoria

2023

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Redox-Driven Signaling: 2-Oxo Acid Dehydrogenase Complexes as Sensors and Transmitters of Metabolic Imbalance

Antioxidants & redox signaling, 2019-06, Vol.30 (16), p.1911-1947

Bunik, Victoria I.

2019

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A challenging interplay between basic research, technologies and medical education to provide therapies based on disease mechanisms

Frontiers in medicine, 2024-08, Vol.11, p.1464672

Bunik, Victoria I

2024

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Metabolic control exerted by the 2-oxoglutarate dehydrogenase reaction: a cross-kingdom comparison of the crossroad between energy production and nitrogen assimilation

Biochemical journal, 2009-09, Vol.422 (3), p.405-421

2009

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Structural Basis for the Binding of Allosteric Activators Leucine and ADP to Mammalian Glutamate Dehydrogenase

International journal of molecular sciences, 2022-09, Vol.23 (19), p.11306

2022

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Editorial: Experts' opinion in medicine 2022

Frontiers in medicine, 2023-10, Vol.10, p.1296196-1296196

Bunik, Victoria I.

2023

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The 2-Oxoacid Dehydrogenase Complexes in Mitochondria Can Produce Superoxide/Hydrogen Peroxide at Much Higher Rates Than Complex I

The Journal of biological chemistry, 2014-03, Vol.289 (12), p.8312-8325

2014

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Daytime Dependence of the Activity of the Rat Brain Pyruvate Dehydrogenase Corresponds to the Mitochondrial Sirtuin 3 Level and Acetylation of Brain Proteins, All Regulated by Thiamine Administration Decreasing Phosphorylation of PDHA Ser293

International journal of molecular sciences, 2021-07, Vol.22 (15), p.8006

2021

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Thiamin diphosphate‐dependent enzymes: from enzymology to metabolic regulation, drug design and disease models

The FEBS journal, 2013-12, Vol.280 (24), p.6412-6442

2013

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Editorial: Women in science - translational medicine 2021

Frontiers in medicine, 2022-09, Vol.9, p.1021894-1021894

2022

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Advantages of formate dehydrogenase reaction for efficient NAD+ quantification in biological samples

Analytical biochemistry, 2020-08, Vol.603, p.113797-113797, Article 113797

2020

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The Brain Protein Acylation System Responds to Seizures in the Rat Model of PTZ-Induced Epilepsy

International journal of molecular sciences, 2022-10, Vol.23 (20), p.12302

2022

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Conformational transitions in the active site of mycobacterial 2-oxoglutarate dehydrogenase upon binding phosphonate analogues of 2-oxoglutarate: From a Michaelis-like complex to ThDP adducts

Journal of structural biology, 2019-11, Vol.208 (2), p.182-190

2019

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Posttranslational Acylations of the Rat Brain Transketolase Discriminate the Enzyme Responses to Inhibitors of ThDP-Dependent Enzymes or Thiamine Transport

International journal of molecular sciences, 2024-01, Vol.25 (2), p.917

2024

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Activation of Mitochondrial 2-Oxoglutarate Dehydrogenase by Cocarboxylase in Human Lung Adenocarcinoma Cells A549 Is p53/p21-Dependent and Impairs Cellular Redox State, Mimicking the Cisplatin Action

International journal of molecular sciences, 2020-05, Vol.21 (11), p.3759

2020

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Protein–Protein Interfaces as Druggable Targets: A Common Motif of the Pyridoxal-5′-Phosphate-Dependent Enzymes to Receive the Coenzyme from Its Producers

Biochemistry (Moscow), 2023-07, Vol.88 (7), p.1022-1033

2023

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Regulation of p53 Function by Formation of Non-Nuclear Heterologous Protein Complexes

Biomolecules (Basel, Switzerland), 2022-02, Vol.12 (2), p.327

2022

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Thiamine preserves mitochondrial function in a rat model of traumatic brain injury, preventing inactivation of the 2-oxoglutarate dehydrogenase complex

Biochimica et biophysica acta. Bioenergetics, 2018-09, Vol.1859 (9), p.925-931

2018

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Generation of superoxide and hydrogen peroxide by side reactions of mitochondrial 2-oxoacid dehydrogenase complexes in isolation and in cells

Biological chemistry, 2018-04, Vol.399 (5), p.407-420

2018

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Synthetic analogues of 2-oxo acids discriminate metabolic contribution of the 2-oxoglutarate and 2-oxoadipate dehydrogenases in mammalian cells and tissues

Scientific reports, 2020-02, Vol.10 (1), p.1886-1886, Article 1886

2020

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Production of superoxide/hydrogen peroxide by the mitochondrial 2-oxoadipate dehydrogenase complex

Free radical biology & medicine, 2016-02, Vol.91, p.247-255

2016

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Molecular characterization of pyridoxine 5′-phosphate oxidase and its pathogenic forms associated with neonatal epileptic encephalopathy

Scientific reports, 2020-08, Vol.10 (1), p.13621, Article 13621

2020

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Pentylenetetrazole-Induced Seizures Are Increased after Kindling, Exhibiting Vitamin-Responsive Correlations to the Post-Seizures Behavior, Amino Acids Metabolism and Key Metabolic Regulators in the Rat Brain

International journal of molecular sciences, 2023-08, Vol.24 (15), p.12405

2023

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Predictive markers for efficiency of the amino-acid deprivation therapies in cancer

Frontiers in medicine, 2022-11, Vol.9, p.1035356-1035356

2022

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Diurnal regulation of the function of the rat brain glutamate dehydrogenase by acetylation and its dependence on thiamine administration

Journal of neurochemistry, 2020-04, Vol.153 (1), p.80-102

2020

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The Therapeutic Potential of Vitamins B1, B3 and B6 in Charcot-Marie-Tooth Disease with the Compromised Status of Vitamin-Dependent Processes

Redox-Driven Signaling: 2-Oxo Acid Dehydrogenase Complexes as Sensors and Transmitters of Metabolic Imbalance

A challenging interplay between basic research, technologies and medical education to provide therapies based on disease mechanisms

Metabolic control exerted by the 2-oxoglutarate dehydrogenase reaction: a cross-kingdom comparison of the crossroad between energy production and nitrogen assimilation

Structural Basis for the Binding of Allosteric Activators Leucine and ADP to Mammalian Glutamate Dehydrogenase

Editorial: Experts' opinion in medicine 2022

The 2-Oxoacid Dehydrogenase Complexes in Mitochondria Can Produce Superoxide/Hydrogen Peroxide at Much Higher Rates Than Complex I

Daytime Dependence of the Activity of the Rat Brain Pyruvate Dehydrogenase Corresponds to the Mitochondrial Sirtuin 3 Level and Acetylation of Brain Proteins, All Regulated by Thiamine Administration Decreasing Phosphorylation of PDHA Ser293

Thiamin diphosphate‐dependent enzymes: from enzymology to metabolic regulation, drug design and disease models

Editorial: Women in science - translational medicine 2021

Advantages of formate dehydrogenase reaction for efficient NAD+ quantification in biological samples

The Brain Protein Acylation System Responds to Seizures in the Rat Model of PTZ-Induced Epilepsy

Conformational transitions in the active site of mycobacterial 2-oxoglutarate dehydrogenase upon binding phosphonate analogues of 2-oxoglutarate: From a Michaelis-like complex to ThDP adducts

Posttranslational Acylations of the Rat Brain Transketolase Discriminate the Enzyme Responses to Inhibitors of ThDP-Dependent Enzymes or Thiamine Transport

Activation of Mitochondrial 2-Oxoglutarate Dehydrogenase by Cocarboxylase in Human Lung Adenocarcinoma Cells A549 Is p53/p21-Dependent and Impairs Cellular Redox State, Mimicking the Cisplatin Action

Protein–Protein Interfaces as Druggable Targets: A Common Motif of the Pyridoxal-5′-Phosphate-Dependent Enzymes to Receive the Coenzyme from Its Producers

Regulation of p53 Function by Formation of Non-Nuclear Heterologous Protein Complexes

Thiamine preserves mitochondrial function in a rat model of traumatic brain injury, preventing inactivation of the 2-oxoglutarate dehydrogenase complex

Generation of superoxide and hydrogen peroxide by side reactions of mitochondrial 2-oxoacid dehydrogenase complexes in isolation and in cells

Synthetic analogues of 2-oxo acids discriminate metabolic contribution of the 2-oxoglutarate and 2-oxoadipate dehydrogenases in mammalian cells and tissues

Production of superoxide/hydrogen peroxide by the mitochondrial 2-oxoadipate dehydrogenase complex

Molecular characterization of pyridoxine 5′-phosphate oxidase and its pathogenic forms associated with neonatal epileptic encephalopathy

Pentylenetetrazole-Induced Seizures Are Increased after Kindling, Exhibiting Vitamin-Responsive Correlations to the Post-Seizures Behavior, Amino Acids Metabolism and Key Metabolic Regulators in the Rat Brain

Predictive markers for efficiency of the amino-acid deprivation therapies in cancer

Diurnal regulation of the function of the rat brain glutamate dehydrogenase by acetylation and its dependence on thiamine administration

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