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Phase Separation and Transcription Regulation: Are Super‐Enhancers and Locus Control Regions Primary Sites of Transcription Complex Assembly?

BioEssays, 2019-01, Vol.41 (1), p.e1800164-n/a

2019

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Old versus new gene therapy for globin disorders

Molecular therapy, 2021-06, Vol.29 (6), p.1933-1934

2021

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Post-translational modification of RNA m6A demethylase ALKBH5 regulates ROS-induced DNA damage response

Nucleic acids research, 2021-06, Vol.49 (10), p.5779-5797

2021

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Coordination of transcription, processing, and export of highly expressed RNAs by distinct biomolecular condensates

Emerging topics in life sciences, 2020-12, Vol.4 (3), p.281-291

2020

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GATA-1 genome-wide occupancy associates with distinct epigenetic profiles in mouse fetal liver erythropoiesis

Nucleic acids research, 2013-05, Vol.41 (9), p.4938-4948

2013

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Engineered Zinc Finger DNA-Binding Domains: Synthesis, Assessment of DNA-Binding Affinity, and Direct Protein Delivery to Mammalian Cells

Methods in molecular biology (Clifton, N.J.), 2017, Vol.1654, p.361

2017

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Cell-cycle specific association of transcription factors and RNA polymerase ii with the human [beta]-globin gene locus

Journal of cellular biochemistry, 2013-09, Vol.114 (9), p.1997-2006

2013

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Locus control region mediated regulation of adult β-globin gene expression

Journal of cellular biochemistry, 2008-09, Vol.105 (1), p.9-16

2008

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Enhancer-Mediated Formation of Nuclear Transcription Initiation Domains

International journal of molecular sciences, 2022-08, Vol.23 (16), p.9290

2022

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Setd1a and NURF mediate chromatin dynamics and gene regulation during erythroid lineage commitment and differentiation

Nucleic acids research, 2016-09, Vol.44 (15), p.7173

2016

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USF1 and hSET1A mediated epigenetic modifications regulate lineage differentiation and HoxB4 transcription

PLoS genetics, 2013-06, Vol.9 (6), p.e1003524-e1003524

2013

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Artificial Zinc Finger DNA Binding Domains: Versatile Tools for Genome Engineering and Modulation of Gene Expression

Journal of cellular biochemistry, 2015-11, Vol.116 (11), p.2435-2444

2015

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Fetal hemoglobin induction in sickle erythroid progenitors using a synthetic zinc finger DNA-binding domain

Haematologica (Roma), 2018-09, Vol.103 (9), p.e384-e387

2018

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Super-enhancer mediated regulation of adult β-globin gene expression: the role of eRNA and Integrator

Nucleic acids research, 2021-02, Vol.49 (3), p.1383-1396

2021

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HoxBlinc RNA Recruits Set1/MLL Complexes to Activate Hox Gene Expression Patterns and Mesoderm Lineage Development

Cell reports (Cambridge), 2016-01, Vol.14 (1), p.103-114

2016

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TFII-I/Gtf2i and Erythro-Megakaryopoiesis

Frontiers in physiology, 2020-09, Vol.11, p.590180-590180

2020

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Corepressor CtBP and Nuclear Speckle Protein Pnn/DRS Differentially Modulate Transcription and Splicing of the E-Cadherin Gene

Molecular and Cellular Biology, 2008-03, Vol.28 (5), p.1584-1595

2008

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Intrinsic and extrinsic effects of mafG deficiency on hematopoietic recovery following bone marrow transplant

Experimental hematology, 2010-12, Vol.38 (12), p.1251-1260

2010

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LATS kinase-mediated CTCF phosphorylation and selective loss of genomic binding

Science advances, 2020-02, Vol.6 (8), p.eaaw4651-eaaw4651

2020

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Functional interrelationship between TFII‐I and E2F transcription factors at specific cell cycle gene loci

Journal of cellular biochemistry, 2018-01, Vol.119 (1), p.712-722

2018

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Abstract 2064: Modulation of TAL1 Gene Expression in T-ALL JURKAT Cells Using Synthetic Zinc Finger DNA-Binding Proteins

The Journal of biological chemistry, 2023, Vol.299 (3), p.104385, Article 104385

2023

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Engineering Globin Gene Expression

Molecular therapy. Methods & clinical development, 2019-03, Vol.12, p.102-110

2019

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Identification of a Novel Enhancer/Chromatin Opening Element Associated with High-Level γ-Globin Gene Expression

Molecular and cellular biology, 2018-10, Vol.38 (19)

2018

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Mechanisms of Pol II Recruitment to the Human Beta-Globin Locus Control Region Super-Enhancer

UF Journal of Undergraduate Research, 2023-10, Vol.25

2023

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Neutralizing the function of a β-globin–associated cis-regulatory DNA element using an artificial zinc finger DNA-binding domain

Proceedings of the National Academy of Sciences - PNAS, 2012-10, Vol.109 (44), p.17948-17953

2012

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Phase Separation and Transcription Regulation: Are Super‐Enhancers and Locus Control Regions Primary Sites of Transcription Complex Assembly?

Old versus new gene therapy for globin disorders

Post-translational modification of RNA m6A demethylase ALKBH5 regulates ROS-induced DNA damage response

Coordination of transcription, processing, and export of highly expressed RNAs by distinct biomolecular condensates

GATA-1 genome-wide occupancy associates with distinct epigenetic profiles in mouse fetal liver erythropoiesis

Engineered Zinc Finger DNA-Binding Domains: Synthesis, Assessment of DNA-Binding Affinity, and Direct Protein Delivery to Mammalian Cells

Cell-cycle specific association of transcription factors and RNA polymerase ii with the human [beta]-globin gene locus

Locus control region mediated regulation of adult β-globin gene expression

Enhancer-Mediated Formation of Nuclear Transcription Initiation Domains

Setd1a and NURF mediate chromatin dynamics and gene regulation during erythroid lineage commitment and differentiation

USF1 and hSET1A mediated epigenetic modifications regulate lineage differentiation and HoxB4 transcription

Artificial Zinc Finger DNA Binding Domains: Versatile Tools for Genome Engineering and Modulation of Gene Expression

Fetal hemoglobin induction in sickle erythroid progenitors using a synthetic zinc finger DNA-binding domain

Super-enhancer mediated regulation of adult β-globin gene expression: the role of eRNA and Integrator

HoxBlinc RNA Recruits Set1/MLL Complexes to Activate Hox Gene Expression Patterns and Mesoderm Lineage Development

TFII-I/Gtf2i and Erythro-Megakaryopoiesis

Corepressor CtBP and Nuclear Speckle Protein Pnn/DRS Differentially Modulate Transcription and Splicing of the E-Cadherin Gene

Intrinsic and extrinsic effects of mafG deficiency on hematopoietic recovery following bone marrow transplant

LATS kinase-mediated CTCF phosphorylation and selective loss of genomic binding

Functional interrelationship between TFII‐I and E2F transcription factors at specific cell cycle gene loci

Abstract 2064: Modulation of TAL1 Gene Expression in T-ALL JURKAT Cells Using Synthetic Zinc Finger DNA-Binding Proteins

Engineering Globin Gene Expression

Identification of a Novel Enhancer/Chromatin Opening Element Associated with High-Level γ-Globin Gene Expression

Mechanisms of Pol II Recruitment to the Human Beta-Globin Locus Control Region Super-Enhancer

Neutralizing the function of a β-globin–associated cis-regulatory DNA element using an artificial zinc finger DNA-binding domain

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