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Cascade Reactions in Total Synthesis

Angewandte Chemie (International ed.), 2006-11, Vol.45 (43), p.7134-7186

2006

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Palladium-Catalyzed Cross-Coupling Reactions in Total Synthesis

Angewandte Chemie (International ed.), 2005-07, Vol.44 (29), p.4442-4489

2005

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Metathesis Reactions in Total Synthesis

Angewandte Chemie (International ed.), 2005-07, Vol.44 (29), p.4490-4527

2005

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CRTH2 Antagonist MK-7246: A Synthetic Evolution from Discovery through Development

Journal of organic chemistry, 2012-03, Vol.77 (5), p.2299-2309

2012

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Enantioselective Synthesis of (1R,2S)-1-Amino-2-vinylcyclopropanecarboxylic Acid Ethyl Ester (Vinyl-ACCA-OEt) by Asymmetric Phase-Transfer Catalyzed Cyclopropanation of (E)-N-Phenylmethyleneglycine Ethyl Ester

Organic process research & development, 2010-05, Vol.14 (3), p.692-700

2010

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A kinase-cGAS cascade to synthesize a therapeutic STING activator

Nature (London), 2022-03, Vol.603 (7901), p.439-444

2022

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Orally Bioavailable Macrocyclic Peptide That Inhibits Binding of PCSK9 to the Low Density Lipoprotein Receptor

Circulation (New York, N.Y.), 2023-07, Vol.148 (2), p.144-158

2023

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Synthesis of iso-epoxy-amphidinolide N and des-epoxy-caribenolide I structures. Initial forays

Organic & biomolecular chemistry, 2006-01, Vol.4 (11), p.2119-2157

2006

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Considerations for Starting Material Designation for Drug-Linkers in Antibody–Drug Conjugates

Organic process research & development, 2023-07, Vol.27 (7), p.1269-1275

2023

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Process Development of C–N Cross-Coupling and Enantioselective Biocatalytic Reactions for the Asymmetric Synthesis of Niraparib

Organic process research & development, 2014-01, Vol.18 (1), p.215-227

2014

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A high-yielding method for the preparation of isoxazolopyridin-3-amine derivatives

Green chemistry : an international journal and green chemistry resource : GC, 2016-01, Vol.18 (18), p.4941-4946

2016

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Recent advances in biomimetic natural product synthesis

Natural product reports, 2008-01, Vol.25 (2), p.254-297

2008

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Synthesis of iso-epoxy-amphidinolide N and des-epoxy-caribenolide I structures. Revised strategy and final stages

Organic & biomolecular chemistry, 2006-01, Vol.4 (11), p.2158-2183

2006

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Convergent, Kilogram Scale Synthesis of an Akt Kinase Inhibitor

Organic process research & development, 2012-05, Vol.16 (5), p.1069-1081

2012

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Facile functionalization at the C2 position of a highly substituted benzofuran

Tetrahedron letters, 2014-04, Vol.55 (14), p.2212-2216

2014

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Studies towards the biomimetic synthesis of the nonadrides CP-225,917 and CP-263,114

Tetrahedron, 2001-08, Vol.57 (34), p.7409-7416

2001

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A Cascade Approach to Cyclic Aminonitrones: Reaction Discovery, Mechanism, and Scope

Organic letters, 2009-08, Vol.11 (15), p.3194-3197

2009

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Strategies for UF/DF-Based Impurity Removal in the Post-conjugation Purification of Antibody–Drug Conjugates

Organic process research & development, 2023-07, Vol.27 (7), p.1258-1268

2023

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A multicomponent coupling strategy suitable for the synthesis of the triene component of the oxazolomycin antibiotics

Organic & biomolecular chemistry, 2003-11, Vol.1 (21), p.3726-3737

2003

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Drug-Linkers in Antibody–Drug Conjugates: Perspective on Current Industry Practices

Organic process research & development, 2023-07, Vol.27 (7), p.1248-1257

2023

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Risk Assessment and Control of N‑Nitrosamines in Antibody–Drug Conjugates: Current Industry Practices

Organic process research & development, 2024-08, Vol.28 (8), p.3078-3084

2024

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Risk Evaluation of N‑Nitrosamines in Drug-Linker Intermediates Used To Generate Antibody–Drug Conjugates

Organic process research & development, 2024-08, Vol.28 (8), p.3085-3093

2024

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A high-yielding method for the preparation of isoxazolopyridin-3-amine derivativesElectronic supplementary information (ESI) available. See DOI: 10.1039/c6gc01125j

2016-09

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Kaskadenreaktionen in der Totalsynthese

Angewandte Chemie, 2006-11, Vol.118 (43), p.7292-7344

2006

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Abstract 288: Use of hiPSC-Derived Cardiomyocytes to Explore Functional Cardiotoxicities of Direct Acting Antiviral Nucleoside Based Structures

Circulation research, 2017-07, Vol.121 (suppl_1)

2017

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Cascade Reactions in Total Synthesis

Palladium-Catalyzed Cross-Coupling Reactions in Total Synthesis

Metathesis Reactions in Total Synthesis

CRTH2 Antagonist MK-7246: A Synthetic Evolution from Discovery through Development

Enantioselective Synthesis of (1R,2S)-1-Amino-2-vinylcyclopropanecarboxylic Acid Ethyl Ester (Vinyl-ACCA-OEt) by Asymmetric Phase-Transfer Catalyzed Cyclopropanation of (E)-N-Phenylmethyleneglycine Ethyl Ester

A kinase-cGAS cascade to synthesize a therapeutic STING activator

Orally Bioavailable Macrocyclic Peptide That Inhibits Binding of PCSK9 to the Low Density Lipoprotein Receptor

Synthesis of iso-epoxy-amphidinolide N and des-epoxy-caribenolide I structures. Initial forays

Considerations for Starting Material Designation for Drug-Linkers in Antibody–Drug Conjugates

Process Development of C–N Cross-Coupling and Enantioselective Biocatalytic Reactions for the Asymmetric Synthesis of Niraparib

A high-yielding method for the preparation of isoxazolopyridin-3-amine derivatives

Recent advances in biomimetic natural product synthesis

Synthesis of iso-epoxy-amphidinolide N and des-epoxy-caribenolide I structures. Revised strategy and final stages

Convergent, Kilogram Scale Synthesis of an Akt Kinase Inhibitor

Facile functionalization at the C2 position of a highly substituted benzofuran

Studies towards the biomimetic synthesis of the nonadrides CP-225,917 and CP-263,114

A Cascade Approach to Cyclic Aminonitrones: Reaction Discovery, Mechanism, and Scope

Strategies for UF/DF-Based Impurity Removal in the Post-conjugation Purification of Antibody–Drug Conjugates

A multicomponent coupling strategy suitable for the synthesis of the triene component of the oxazolomycin antibiotics

Drug-Linkers in Antibody–Drug Conjugates: Perspective on Current Industry Practices

Risk Assessment and Control of N‑Nitrosamines in Antibody–Drug Conjugates: Current Industry Practices

Risk Evaluation of N‑Nitrosamines in Drug-Linker Intermediates Used To Generate Antibody–Drug Conjugates

A high-yielding method for the preparation of isoxazolopyridin-3-amine derivativesElectronic supplementary information (ESI) available. See DOI: 10.1039/c6gc01125j

Kaskadenreaktionen in der Totalsynthese

Abstract 288: Use of hiPSC-Derived Cardiomyocytes to Explore Functional Cardiotoxicities of Direct Acting Antiviral Nucleoside Based Structures

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