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MEK and PI3K-AKT inhibitors synergistically block activated IL7 receptor signaling in T-cell acute lymphoblastic leukemia

Leukemia, 2016-09, Vol.30 (9), p.1832-1843

2016

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Minifragment plating of the fibula in unstable ankle fractures

Archives of orthopaedic and trauma surgery, 2023-03, Vol.143 (3), p.1499-1504

2023

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Compound selectivity and target residence time of kinase inhibitors studied with surface plasmon resonance

European journal of cancer (1990), 2016-12, Vol.69, p.S79-S79

2016

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The unique binding mode of NTRC 0066-0, a novel inhibitor of the spindle assembly checkpoint kinase TTK (Mps1), leads to long target residence time and potent anti-tumor activity

European journal of cancer (1990), 2016-07, Vol.61, p.S129-S129

2016

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Ruthenium-Catalyzed Olefin Metathesis in Ionic Liquids

Organic letters, 2001-11, Vol.3 (23), p.3785-3787

2001

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Synthetic heparin derivatives as new anticoagulant drugs

Drug discovery today, 2005-06, Vol.10 (11), p.769-779

2005

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Randomized clinical trial of observational versus antibiotic treatment for a first episode of CT‐proven uncomplicated acute diverticulitis

British journal of surgery, 2017-01, Vol.104 (1), p.52-61

2017

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42P BAL0891: A novel, small molecule, dual TTK/PLK1 mitotic checkpoint inhibitor (MCI) with potent single agent activity

Annals of oncology, 2022-03, Vol.33, p.S18-S19

2022

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Serious game versus standard care for rehabilitation after distal radius fractures: a protocol for a multicentre randomised controlled trial

BMJ open, 2021-03, Vol.11 (3), p.e042629-e042629

2021

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235 - Compound selectivity and target residence time of kinase inhibitors studied with surface plasmon resonance

European journal of cancer (1990), 2016-12, Vol.69, p.S79-S79

2016

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586 - The unique binding mode of NTRC 0066-0, a novel inhibitor of the spindle assembly checkpoint kinase TTK (Mps1), leads to long target residence time and potent anti-tumor activity

European journal of cancer (1990), 2016-07, Vol.61, p.S129-S129

2016

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Identification of selective inhibitors of the spindle assembly checkpoint kinase TTK (Mps1) for treatment of triple negative breast cancer

Annals of oncology, 2015-03, Vol.26, p.ii28

2015

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Synthesis of heparin-like antithrombotics having perphosphorylated thrombin binding domains

Bioorganic & medicinal chemistry, 1999-09, Vol.7 (9), p.1881-1890

1999

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Synthesis and inhibitory effect of a trisubstrate transition state analogue for UDP glucuronosyltransferases

Bioorganic & medicinal chemistry letters, 1997-06, Vol.7 (12), p.1501-1506

1997

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Cell panel profiling of pre-clinical and clinical anti-cancer agents reveals conserved therapeutic clusters and differentiates the mechanism of action of different PI3K/mTOR, Aurora kinase and EZH2 inhibitors

European journal of cancer (1990), 2016-12, Vol.69, p.S24-S24

2016

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Design and synthesis of a novel synthetic NAPAP-penta-saccharide conjugate displaying a dual antithrombotic action

Bioorganic & medicinal chemistry letters, 1999-07, Vol.9 (14), p.2013-2018

1999

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Non-steroidal steroid receptor modulators

Current medicinal chemistry, 2005-01, Vol.12 (9), p.1017-1075

2005

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PO-495 Prediction of chemotherapy sensitivity on ascites of ovarian cancer patients

ESMO open, 2018-07, Vol.3 (Suppl 2), p.A424-A424

2018

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PO-484 Development of a two-step screening-and-confirmation approach to efficiently identify synergistic drug combinations with the PARP inhibitor niraparib

ESMO open, 2018-07, Vol.3 (Suppl 2), p.A211-A212

2018

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PO-456 Cell line panel profiling of all clinically approved kinase inhibitors for cancer treatment

ESMO open, 2018-07, Vol.3 (Suppl 2), p.A201-A201

2018

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Development of a novel ionic support and its application in the ionic liquid phase assisted synthesis of a potent antithrombotic

Tetrahedron letters, 2004-03, Vol.45 (10), p.2171-2175

2004

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Design and synthesis of a possible mimic of a thrombin-binding DNA aptamer

Bioorganic & medicinal chemistry letters, 1997-08, Vol.7 (15), p.2027-2032

1997

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Identification of Ligands for the Orphan Nuclear Receptor GCNF

Medicinal chemistry research, 2004-01, Vol.13 (3-4), p.210-215

2004

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Synthesis of a Pentasaccharide-Oligonucleotide Conjugate: A Novel Antithrombotic Agent

Chemistry : a European journal, 1996-12, Vol.2 (12), p.1572-1577

1996

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Comparison of the cancer gene targeting and biochemical selectivities of all targeted kinase inhibitors approved for clinical use

PloS one, 2014-03, Vol.9 (3), p.e92146-e92146

2014

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MEK and PI3K-AKT inhibitors synergistically block activated IL7 receptor signaling in T-cell acute lymphoblastic leukemia

Minifragment plating of the fibula in unstable ankle fractures

Compound selectivity and target residence time of kinase inhibitors studied with surface plasmon resonance

The unique binding mode of NTRC 0066-0, a novel inhibitor of the spindle assembly checkpoint kinase TTK (Mps1), leads to long target residence time and potent anti-tumor activity

Ruthenium-Catalyzed Olefin Metathesis in Ionic Liquids

Synthetic heparin derivatives as new anticoagulant drugs

Randomized clinical trial of observational versus antibiotic treatment for a first episode of CT‐proven uncomplicated acute diverticulitis

42P BAL0891: A novel, small molecule, dual TTK/PLK1 mitotic checkpoint inhibitor (MCI) with potent single agent activity

Serious game versus standard care for rehabilitation after distal radius fractures: a protocol for a multicentre randomised controlled trial

235 - Compound selectivity and target residence time of kinase inhibitors studied with surface plasmon resonance

586 - The unique binding mode of NTRC 0066-0, a novel inhibitor of the spindle assembly checkpoint kinase TTK (Mps1), leads to long target residence time and potent anti-tumor activity

Identification of selective inhibitors of the spindle assembly checkpoint kinase TTK (Mps1) for treatment of triple negative breast cancer

Synthesis of heparin-like antithrombotics having perphosphorylated thrombin binding domains

Synthesis and inhibitory effect of a trisubstrate transition state analogue for UDP glucuronosyltransferases

Cell panel profiling of pre-clinical and clinical anti-cancer agents reveals conserved therapeutic clusters and differentiates the mechanism of action of different PI3K/mTOR, Aurora kinase and EZH2 inhibitors

Design and synthesis of a novel synthetic NAPAP-penta-saccharide conjugate displaying a dual antithrombotic action

Non-steroidal steroid receptor modulators

PO-495 Prediction of chemotherapy sensitivity on ascites of ovarian cancer patients

PO-484 Development of a two-step screening-and-confirmation approach to efficiently identify synergistic drug combinations with the PARP inhibitor niraparib

PO-456 Cell line panel profiling of all clinically approved kinase inhibitors for cancer treatment

Development of a novel ionic support and its application in the ionic liquid phase assisted synthesis of a potent antithrombotic

Design and synthesis of a possible mimic of a thrombin-binding DNA aptamer

Identification of Ligands for the Orphan Nuclear Receptor GCNF

Synthesis of a Pentasaccharide-Oligonucleotide Conjugate: A Novel Antithrombotic Agent

Comparison of the cancer gene targeting and biochemical selectivities of all targeted kinase inhibitors approved for clinical use

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