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Significance of transcytosis in Alzheimer's disease: BACE1 takes the scenic route to axons

BioEssays, 2015-08, Vol.37 (8), p.888-898

2015

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Aberrant accrual of BIN1 near Alzheimer’s disease amyloid deposits in transgenic models

Brain pathology (Zurich, Switzerland), 2019-07, Vol.29 (4), p.485-501

2019

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Axonal BACE1 dynamics and targeting in hippocampal neurons: a role for Rab11 GTPase

Molecular neurodegeneration, 2014-01, Vol.9 (1), p.1-1, Article 1

2014

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Presynaptic dystrophic neurites surrounding amyloid plaques are sites of microtubule disruption, BACE1 elevation, and increased Aβ generation in Alzheimer’s disease

Acta neuropathologica, 2016-08, Vol.132 (2), p.235-256

2016

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A Function for EHD Family Proteins in Unidirectional Retrograde Dendritic Transport of BACE1 and Alzheimer’s Disease Aβ Production

Cell reports (Cambridge), 2013-12, Vol.5 (6), p.1552-1563

2013

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Nuclear Factor-κB Regulates βAPP and β- and γ-Secretases Differently at Physiological and Supraphysiological Aβ Concentrations

The Journal of biological chemistry, 2012-07, Vol.287 (29), p.24573-24584

2012

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Sorting the role of SORLA in Alzheimer's disease

Science translational medicine, 2014-02, Vol.6 (223), p.223fs8

2014

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Lack of BACE1 S-palmitoylation reduces amyloid burden and mitigates memory deficits in transgenic mouse models of Alzheimer’s disease

Proceedings of the National Academy of Sciences - PNAS, 2017-11, Vol.114 (45), p.E9665-E9674

2017

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Predominant expression of Alzheimer's disease-associated BIN1 in mature oligodendrocytes and localization to white matter tracts

Molecular neurodegeneration, 2016-08, Vol.11 (1), p.59-59, Article 59

2016

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Ca2+ Influx through Store-operated Ca2+ Channels Reduces Alzheimer Disease β-Amyloid Peptide Secretion

The Journal of biological chemistry, 2013-09, Vol.288 (37), p.26955-26966

2013

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Dual Leucine Zipper Kinase Is Constitutively Active in the Adult Mouse Brain and Has Both Stress-Induced and Homeostatic Functions

International journal of molecular sciences, 2020-07, Vol.21 (14), p.4849

2020

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Presynaptic dystrophic neurites surrounding amyloid plaques are sites of microtubule disruption, BACE1 elevation, and increased A[beta] generation in Alzheimer's disease

Acta neuropathologica, 2016-08, Vol.132 (2), p.235

2016

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Nuclear factor-κB regulates βAPP and β- and γ-secretases differently at physiological and supraphysiological Aβ concentrations

The Journal of biological chemistry, 2015-12, Vol.290 (50), p.29758-29758

2015

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A Paired RNAi and RabGAP Overexpression Screen Identifies Rab11 as a Regulator of β-Amyloid Production

Cell reports (Cambridge), 2013-12, Vol.5 (6), p.1536-1551

2013

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Nuclear factor-κB regulates βAPP and β- and γ-secretases differently at physiological and supraphysiological Aβ concentrations

The Journal of biological chemistry, 2013-07, Vol.288 (27), p.19645-19645

2013

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De novo and long-term l -Dopa induce both common and distinct striatal gene profiles in the hemiparkinsonian rat

Neurobiology of disease, 2009-05, Vol.34 (2), p.340-350

2009

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Novel Targets for Alzheimer's Disease: A View Beyond Amyloid

Annual review of medicine, 2021-01, Vol.72 (1), p.15-28

2021

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Correction: Predominant expression of Alzheimer's disease-associated BIN1 in mature oligodendrocytes and localization to white matter tracts

Molecular neurodegeneration, 2023-10, Vol.18 (1), p.72-72, Article 72

2023

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NF Kappa B-dependent Control of BACE1 Promoter Transactivation by A beta 42

The Journal of biological chemistry, 2008-04, Vol.283 (15), p.10037-10047

2008

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Pathogenic tau accelerates aging-associated activation of transposable elements in the mouse central nervous system

Progress in neurobiology, 2022-01, Vol.208, p.102181-102181, Article 102181

2022

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NFκB-dependent Control of BACE1 Promoter Transactivation by Aβ42

The Journal of biological chemistry, 2008-04, Vol.283 (15), p.10037-10047

2008

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Inhibition of dual leucine zipper kinase prevents chemotherapy-induced peripheral neuropathy and cognitive impairments

Pain (Amsterdam), 2021-10, Vol.162 (10), p.2599-2612

2021

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Discovery of IACS-52825, a Potent and Selective DLK Inhibitor for Treatment of Chemotherapy-Induced Peripheral Neuropathy

Journal of medicinal chemistry, 2023-07, Vol.66 (14), p.9954-9971

2023

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EXPRESSION OF THE DUAL LEUCINE ZIPPER KINASE IN DYSTROPHIC NEURITES AND AXONAL BEADING DURING PATHOLOGY PROGRESSION IN ALZHEIMER’S DISEASE

Alzheimer's & dementia, 2018-07, Vol.14 (7), p.P732-P732

2018

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P2‐167: EXPRESSION OF THE DUAL LEUCINE ZIPPER KINASE IN DYSTROPHIC NEURITES AND AXONAL BEADING DURING PATHOLOGY PROGRESSION IN ALZHEIMER'S DISEASE

Alzheimer's & dementia, 2018-07, Vol.14 (7S_Part_13), p.P732-P732

2018

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Significance of transcytosis in Alzheimer's disease: BACE1 takes the scenic route to axons

Aberrant accrual of BIN1 near Alzheimer’s disease amyloid deposits in transgenic models

Axonal BACE1 dynamics and targeting in hippocampal neurons: a role for Rab11 GTPase

Presynaptic dystrophic neurites surrounding amyloid plaques are sites of microtubule disruption, BACE1 elevation, and increased Aβ generation in Alzheimer’s disease

A Function for EHD Family Proteins in Unidirectional Retrograde Dendritic Transport of BACE1 and Alzheimer’s Disease Aβ Production

Nuclear Factor-κB Regulates βAPP and β- and γ-Secretases Differently at Physiological and Supraphysiological Aβ Concentrations

Sorting the role of SORLA in Alzheimer's disease

Lack of BACE1 S-palmitoylation reduces amyloid burden and mitigates memory deficits in transgenic mouse models of Alzheimer’s disease

Predominant expression of Alzheimer's disease-associated BIN1 in mature oligodendrocytes and localization to white matter tracts

Ca2+ Influx through Store-operated Ca2+ Channels Reduces Alzheimer Disease β-Amyloid Peptide Secretion

Dual Leucine Zipper Kinase Is Constitutively Active in the Adult Mouse Brain and Has Both Stress-Induced and Homeostatic Functions

Presynaptic dystrophic neurites surrounding amyloid plaques are sites of microtubule disruption, BACE1 elevation, and increased A[beta] generation in Alzheimer's disease

Nuclear factor-κB regulates βAPP and β- and γ-secretases differently at physiological and supraphysiological Aβ concentrations

A Paired RNAi and RabGAP Overexpression Screen Identifies Rab11 as a Regulator of β-Amyloid Production

Nuclear factor-κB regulates βAPP and β- and γ-secretases differently at physiological and supraphysiological Aβ concentrations

De novo and long-term l -Dopa induce both common and distinct striatal gene profiles in the hemiparkinsonian rat

Novel Targets for Alzheimer's Disease: A View Beyond Amyloid

Correction: Predominant expression of Alzheimer's disease-associated BIN1 in mature oligodendrocytes and localization to white matter tracts

NF Kappa B-dependent Control of BACE1 Promoter Transactivation by A beta 42

Pathogenic tau accelerates aging-associated activation of transposable elements in the mouse central nervous system

NFκB-dependent Control of BACE1 Promoter Transactivation by Aβ42

Inhibition of dual leucine zipper kinase prevents chemotherapy-induced peripheral neuropathy and cognitive impairments

Discovery of IACS-52825, a Potent and Selective DLK Inhibitor for Treatment of Chemotherapy-Induced Peripheral Neuropathy

EXPRESSION OF THE DUAL LEUCINE ZIPPER KINASE IN DYSTROPHIC NEURITES AND AXONAL BEADING DURING PATHOLOGY PROGRESSION IN ALZHEIMER’S DISEASE

P2‐167: EXPRESSION OF THE DUAL LEUCINE ZIPPER KINASE IN DYSTROPHIC NEURITES AND AXONAL BEADING DURING PATHOLOGY PROGRESSION IN ALZHEIMER'S DISEASE

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