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Rational design of small molecules as vaccine adjuvants

Science translational medicine, 2014-11, Vol.6 (263), p.263ra160

2014

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A new strategy for preparing a tailored meningococcal ACWY conjugate vaccine for clinical testing

Vaccine, 2020-05, Vol.38 (23), p.3930-3933

2020

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Clinically proven specification setting for a meningococcal serogroup a conjugate vaccine

Vaccine, 2022-05, Vol.40 (24), p.3366-3371

2022

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The Preparation and Physicochemical Characterization of Aluminum Hydroxide/TLR7a, a Novel Vaccine Adjuvant Comprising a Small Molecule Adsorbed to Aluminum Hydroxide

Journal of pharmaceutical sciences, 2018-06, Vol.107 (6), p.1577-1585

2018

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Novel adjuvant Alum-TLR7 significantly potentiates immune response to glycoconjugate vaccines

Scientific reports, 2016-07, Vol.6 (1), p.29063-29063, Article 29063

2016

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Aluminum Adjuvant Dose Guidelines in Vaccine Formulation for Preclinical Evaluations

Journal of pharmaceutical sciences, 2012-01, Vol.101 (1), p.17-20

2012

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The preparation and characterization of PLG nanoparticles with an entrapped synthetic TLR7 agonist and their preclinical evaluation as adjuvant for an adsorbed DTaP vaccine

European journal of pharmaceutics and biopharmaceutics, 2016-08, Vol.105, p.1-8

2016

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Flow cytometry: An alternative method for direct quantification of antigens adsorbed to aluminum hydroxide adjuvant

Analytical biochemistry, 2011-11, Vol.418 (2), p.224-230

2011

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Surface Characterization of Carbohydrate Microarrays

Langmuir, 2010-11, Vol.26 (22), p.17143-17155

2010

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Determination of Carbohydrate-Binding Preferences of Human Galectins with Carbohydrate Microarrays

Chembiochem : a European journal of chemical biology, 2010-07, Vol.11 (11), p.1563-1573

2010

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Preparation of tetraalkylformamidinium salts and related species as precursors to stable carbenes

Perkin 1 : an international journal of organic and bio-organic chemistry, 2001 (14), p.1586-1593

2001

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DPP-IV-resistant, long-acting oxyntomodulin derivatives

Journal of peptide science, 2011-04, Vol.17 (4), p.270-280

2011

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ApoA-I mimetic peptides promote pre-β HDL formation in vivo causing remodeling of HDL and triglyceride accumulation at higher dose

Bioorganic & medicinal chemistry, 2010-12, Vol.18 (24), p.8669-8678

2010

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Complexation of stable carbenes with alkali metals

Chemical communications (Cambridge, England), 1999-02 (3), p.241-242

1999

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Novel Camptothecin Analogue (Gimatecan)-Containing Liposomes Prepared by the Ethanol Injection Method

Journal of liposome research, 2004, Vol.14 (1-2), p.87-109

2004

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The antigenic activity of glycosphingolipids with tetrasaccharide sugars from Sphingomonas bacteria to natural killer T cells

The FASEB journal, 2008-03, Vol.22 (S1)

2008

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2-[Dimethyl(2-naphthylmethyl)silyl]ethoxy Carbonate (NSEC) as a New Mode of Hydroxyl Group Protection 1

Journal of carbohydrate chemistry, 2005-08, Vol.24 (4-6), p.441-462

2005

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Effect of Tryptophan Oligopeptides on the Size Distribution of POPC Liposomes: A Dynamic Light Scattering and Turbidimetric Study

Journal of liposome research, 2005, Vol.15 (1-2), p.29-47

2005

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Effect of tryptophan oligopeptides on the size distribution of POPC liposomes: a dynamic light scattering and turbidimetric study

Journal of liposome research, 2005-01, Vol.15 (1-2), p.29-47

2005

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2-[Dimethyl(2-naphthylmethyl)silyl]ethoxy Carbonate (NSEC) as a New Mode of Hydroxyl Group Protection

Journal of carbohydrate chemistry, 2005-08, Vol.24 (4-6), p.441-462

2005

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Activation and stabilization of α‐chymotrypsin by cationic additives

European journal of biochemistry, 2001-12, Vol.268 (24), p.6491-6497

2001

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ChemInform Abstract: Glycosylation on Polymer Supports

ChemInform, 2008-08, Vol.39 (33), p.no-no

2008

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Rational design of small molecules as vaccine adjuvants

Identification of MK-5710 ((8aS)-8a-methyl-1,3-dioxo-2-[(1S,2R)-2-phenylcyclo- propyl]-N-(1-phenyl-1H-pyrazol-5-yl)hexahydro-imidazo[1,5-a]pyrazine-7(1H)-carboxamide), a potent smoothened antagonist for use in Hedgehog pathway dependent malignancies, Part 2

A new strategy for preparing a tailored meningococcal ACWY conjugate vaccine for clinical testing

Clinically proven specification setting for a meningococcal serogroup a conjugate vaccine

The Preparation and Physicochemical Characterization of Aluminum Hydroxide/TLR7a, a Novel Vaccine Adjuvant Comprising a Small Molecule Adsorbed to Aluminum Hydroxide

Novel adjuvant Alum-TLR7 significantly potentiates immune response to glycoconjugate vaccines

Aluminum Adjuvant Dose Guidelines in Vaccine Formulation for Preclinical Evaluations

The preparation and characterization of PLG nanoparticles with an entrapped synthetic TLR7 agonist and their preclinical evaluation as adjuvant for an adsorbed DTaP vaccine

Flow cytometry: An alternative method for direct quantification of antigens adsorbed to aluminum hydroxide adjuvant

Surface Characterization of Carbohydrate Microarrays

Determination of Carbohydrate-Binding Preferences of Human Galectins with Carbohydrate Microarrays

Preparation of tetraalkylformamidinium salts and related species as precursors to stable carbenes

DPP-IV-resistant, long-acting oxyntomodulin derivatives

ApoA-I mimetic peptides promote pre-β HDL formation in vivo causing remodeling of HDL and triglyceride accumulation at higher dose

Complexation of stable carbenes with alkali metals

Novel Camptothecin Analogue (Gimatecan)-Containing Liposomes Prepared by the Ethanol Injection Method

The antigenic activity of glycosphingolipids with tetrasaccharide sugars from Sphingomonas bacteria to natural killer T cells

Identification of MK-5710 ((8aS)-8a-methyl-1,3-dioxo-2-[(1S,2R)-2-phenylcyclo- propyl]-N-(1-phenyl-1H-pyrazol-5-yl)hexahydro-imidazo[1,5-a]pyrazi n e-7(1H)-carboxamide), a potent smoothened antagonist for use in Hedgehog pathway dependent malignancies, Part 2

Identification of MK-5710 ((8 aS)-8 a-methyl-1,3-dioxo-2-[(1 S,2 R)-2-phenylcyclo- propyl]- N-(1-phenyl-1 H-pyrazol-5-yl)hexahydro-imidazo[1,5- a]pyrazine-7(1 H)-carboxamide), a potent smoothened antagonist for use in Hedgehog pathway dependent malignancies, Part 2

2-[Dimethyl(2-naphthylmethyl)silyl]ethoxy Carbonate (NSEC) as a New Mode of Hydroxyl Group Protection 1

Effect of Tryptophan Oligopeptides on the Size Distribution of POPC Liposomes: A Dynamic Light Scattering and Turbidimetric Study

Effect of tryptophan oligopeptides on the size distribution of POPC liposomes: a dynamic light scattering and turbidimetric study

2-[Dimethyl(2-naphthylmethyl)silyl]ethoxy Carbonate (NSEC) as a New Mode of Hydroxyl Group Protection

Activation and stabilization of α‐chymotrypsin by cationic additives

ChemInform Abstract: Glycosylation on Polymer Supports

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