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The effects of mutant Ras proteins on the cell signalome

Cancer and metastasis reviews, 2020-12, Vol.39 (4), p.1051-1065

2020

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The transcriptional activity of hepatocyte nuclear factor 4 alpha is inhibited via phosphorylation by ERK1/2

PloS one, 2017-02, Vol.12 (2), p.e0172020-e0172020

2017

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Unveiling epithelial plasticity regulation in lung cancer: Exploring the cross-talk among Tks4 scaffold protein partners

Molecular biology of the cell, 2024-08, Vol.35 (8), p.ar111

2024

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Studying the Association of TKS4 and CD2AP Scaffold Proteins and Their Implications in the Partial Epithelial–Mesenchymal Transition (EMT) Process

International journal of molecular sciences, 2023-10, Vol.24 (20), p.15136

2023

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An in silico molecular docking and simulation study to identify potential anticancer phytochemicals targeting the RAS signaling pathway

PloS one, 2024-09, Vol.19 (9), p.e0310637

2024

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Long noncoding RNA MALAT1 as a ceRNA drives mouse fibroblast activation via the miR-335-3p/P2ry2 axis

PloS one, 2024-08, Vol.19 (8), p.e0308723

2024

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Expression of RAS and RAB interactor 1 (RIN1) in head and neck tumors at selected hospital in Ghana

PloS one, 2024-04, Vol.19 (4), p.e0301295-e0301295

2024

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Role of two modules controlling the interaction between SKAP1 and SRC kinases comparison with SKAP2 architecture and consequences for evolution

PloS one, 2024-03, Vol.19 (3), p.e0296230-e0296230

2024

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The lymphocyte-specific protein tyrosine kinase-specific inhibitor A-770041 attenuates lung fibrosis via the suppression of TGF-β production in regulatory T-cells

PloS one, 2022-10, Vol.17 (10), p.e0275987-e0275987

2022

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Structural disorder in eukaryotes

PloS one, 2012-04, Vol.7 (4), p.e34687-e34687

2012

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Advances in Understanding TKS4 and TKS5: Molecular Scaffolds Regulating Cellular Processes from Podosome and Invadopodium Formation to Differentiation and Tissue Homeostasis

International journal of molecular sciences, 2020-10, Vol.21 (21), p.8117

2020

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Obscurin Rho GEF domains are phosphorylated by MST-family kinases but do not exhibit nucleotide exchange factor activity towards Rho GTPases in vitro

PloS one, 2023-04, Vol.18 (4), p.e0284453-e0284453

2023

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Light-mediated kinetic control reveals the temporal effect of the Raf/MEK/ERK pathway in PC12 cell neurite outgrowth

PloS one, 2014-03, Vol.9 (3), p.e92917-e92917

2014

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Luxeptinib interferes with LYN-mediated activation of SYK and modulates BCR signaling in lymphoma

PloS one, 2023-03, Vol.18 (3), p.e0277003-e0277003

2023

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EGF Regulates the Interaction of Tks4 with Src through Its SH2 and SH3 Domains

Biochemistry (Easton), 2018-07, Vol.57 (28), p.4186-4196

2018

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The RAS-Effector Interface: Isoform-Specific Differences in the Effector Binding Regions

PloS one, 2016-12, Vol.11 (12), p.e0167145-e0167145

2016

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A Novel Cell-Based Model for a Rare Disease: The Tks4-KO Human Embryonic Stem Cell Line as a Frank-Ter Haar Syndrome Model System

International journal of molecular sciences, 2022-08, Vol.23 (15), p.8803

2022

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The long-noncoding RNA MALAT1 regulates TGF-β/Smad signaling through formation of a lncRNA-protein complex with Smads, SETD2 and PPM1A in hepatic cells

PloS one, 2020-01, Vol.15 (1), p.e0228160-e0228160

2020

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SHP-1 tyrosine phosphatase binding to c-Src kinase phosphor-dependent conformations: A comparative structural framework

PloS one, 2023-01, Vol.18 (1), p.e0278448-e0278448

2023

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Contribution of Noncovalent Recognition and Reactivity to the Optimization of Covalent Inhibitors: A Case Study on KRasG12C

ACS chemical biology, 2024-08, Vol.19 (8), p.1743-1756

2024

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SLAMF6 clustering is required to augment T cell activation

PloS one, 2019-06, Vol.14 (6), p.e0218109-e0218109

2019

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Combined Treatment of MCF-7 Cells with AICAR and Methotrexate, Arrests Cell Cycle and Reverses Warburg Metabolism through AMP-Activated Protein Kinase (AMPK) and FOXO1

PloS one, 2016-02, Vol.11 (2), p.e0150232-e0150232

2016

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Cellular Chaperone Function of Intrinsically Disordered Dehydrin ERD14

International journal of molecular sciences, 2021-06, Vol.22 (12), p.6190

2021

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The SH2 domain and kinase activity of JAK2 target JAK2 to centrosome and regulate cell growth and centrosome amplification

PloS one, 2022-01, Vol.17 (1), p.e0261098-e0261098

2022

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RIN3 is a negative regulator of mast cell responses to SCF

PloS one, 2012-11, Vol.7 (11), p.e49615-e49615

2012

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The effects of mutant Ras proteins on the cell signalome

The transcriptional activity of hepatocyte nuclear factor 4 alpha is inhibited via phosphorylation by ERK1/2

Unveiling epithelial plasticity regulation in lung cancer: Exploring the cross-talk among Tks4 scaffold protein partners

Studying the Association of TKS4 and CD2AP Scaffold Proteins and Their Implications in the Partial Epithelial–Mesenchymal Transition (EMT) Process

An in silico molecular docking and simulation study to identify potential anticancer phytochemicals targeting the RAS signaling pathway

Long noncoding RNA MALAT1 as a ceRNA drives mouse fibroblast activation via the miR-335-3p/P2ry2 axis

Expression of RAS and RAB interactor 1 (RIN1) in head and neck tumors at selected hospital in Ghana

Role of two modules controlling the interaction between SKAP1 and SRC kinases comparison with SKAP2 architecture and consequences for evolution

The lymphocyte-specific protein tyrosine kinase-specific inhibitor A-770041 attenuates lung fibrosis via the suppression of TGF-β production in regulatory T-cells

Structural disorder in eukaryotes

Advances in Understanding TKS4 and TKS5: Molecular Scaffolds Regulating Cellular Processes from Podosome and Invadopodium Formation to Differentiation and Tissue Homeostasis

Obscurin Rho GEF domains are phosphorylated by MST-family kinases but do not exhibit nucleotide exchange factor activity towards Rho GTPases in vitro

Light-mediated kinetic control reveals the temporal effect of the Raf/MEK/ERK pathway in PC12 cell neurite outgrowth

Luxeptinib interferes with LYN-mediated activation of SYK and modulates BCR signaling in lymphoma

EGF Regulates the Interaction of Tks4 with Src through Its SH2 and SH3 Domains

The RAS-Effector Interface: Isoform-Specific Differences in the Effector Binding Regions

A Novel Cell-Based Model for a Rare Disease: The Tks4-KO Human Embryonic Stem Cell Line as a Frank-Ter Haar Syndrome Model System

The long-noncoding RNA MALAT1 regulates TGF-β/Smad signaling through formation of a lncRNA-protein complex with Smads, SETD2 and PPM1A in hepatic cells

SHP-1 tyrosine phosphatase binding to c-Src kinase phosphor-dependent conformations: A comparative structural framework

Contribution of Noncovalent Recognition and Reactivity to the Optimization of Covalent Inhibitors: A Case Study on KRasG12C

SLAMF6 clustering is required to augment T cell activation

Combined Treatment of MCF-7 Cells with AICAR and Methotrexate, Arrests Cell Cycle and Reverses Warburg Metabolism through AMP-Activated Protein Kinase (AMPK) and FOXO1

Cellular Chaperone Function of Intrinsically Disordered Dehydrin ERD14

The SH2 domain and kinase activity of JAK2 target JAK2 to centrosome and regulate cell growth and centrosome amplification

RIN3 is a negative regulator of mast cell responses to SCF

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