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Translational immunology: Applying fundamental discoveries to human health and autoimmune diseases

European journal of immunology, 2023-12, Vol.53 (12), p.e2250197-n/a

Buckner, Jane H.

2023

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Immunotherapy: Building a bridge to a cure for type 1 diabetes

Science (American Association for the Advancement of Science), 2021-07, Vol.373 (6554), p.510-516

2021

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Rheumatoid arthritis and the mucosal origins hypothesis: protection turns to destruction

Nature reviews. Rheumatology, 2018-09, Vol.14 (9), p.542-557

2018

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HLA autoimmune risk alleles restrict the hypervariable region of T cell receptors

Nature genetics, 2022-04, Vol.54 (4), p.393-402

2022

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B cell-derived IL-6 initiates spontaneous germinal center formation during systemic autoimmunity

The Journal of experimental medicine, 2017-11, Vol.214 (11), p.3207-3217

2017

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Down syndrome: insights into autoimmune mechanisms

Nature reviews. Rheumatology, 2023-07, Vol.19 (7), p.401-402

2023

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CD4+FOXP3+ T regulatory cells in human autoimmunity: more than a numbers game

The Journal of immunology (1950), 2011-09, Vol.187 (5), p.2061-2066

2011

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IL-6: a cytokine at the crossroads of autoimmunity

Current opinion in immunology, 2018-12, Vol.55, p.9-14

2018

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Genetic basis of defects in immune tolerance underlying the development of autoimmunity

Frontiers in immunology, 2022-08, Vol.13, p.972121-972121

2022

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Immune-related adverse events after immune check point inhibitors: Understanding the intersection with autoimmunity

Immunological reviews, 2023-09, Vol.318 (1), p.81-88

2023

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Low-dose interleukin-2 fosters a dose-dependent regulatory T cell tuned milieu in T1D patients

Journal of autoimmunity, 2015-04, Vol.58, p.48-58

2015

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SARS-CoV-2 mRNA vaccines decouple anti-viral immunity from humoral autoimmunity

Nature communications, 2023-03, Vol.14 (1), p.1299-1299, Article 1299

2023

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The role of PTPN22 risk variant in the development of autoimmunity: finding common ground between mouse and human

The Journal of immunology (1950), 2015-04, Vol.194 (7), p.2977-2984

2015

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Type 1 diabetes immunotherapy using polyclonal regulatory T cells

Science translational medicine, 2015-11, Vol.7 (315), p.315ra189

2015

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The Effector T Cells of Diabetic Subjects Are Resistant to Regulation via CD4+FOXP3+ Regulatory T Cells

The Journal of immunology (1950), 2008-11, Vol.181 (10), p.7350-7355

2008

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Th17 cells: from gut homeostasis to CNS pathogenesis

Trends in immunology, 2022-03, Vol.43 (3), p.167-169

2022

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Complement receptor 2/CD21− human naive B cells contain mostly autoreactive unresponsive clones

Blood, 2010-06, Vol.115 (24), p.5026-5036

2010

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Clinical and experimental treatment of type 1 diabetes

Clinical and experimental immunology, 2022-12, Vol.210 (2), p.105-113

2022

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Clinical and experimental treatment of type 1 diabetes: Perspectives on immunopathology and Clinical and experimental treatment of type 1 diabetes

Clinical and experimental immunology, 2022-12, Vol.210 (2), p.105-113

2022

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The dynamic epigenetic regulation of the inactive X chromosome in healthy human B cells is dysregulated in lupus patients

Proceedings of the National Academy of Sciences - PNAS, 2021-06, Vol.118 (24), p.1

2021

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A disease-associated PTPN22 variant promotes systemic autoimmunity in murine models

The Journal of clinical investigation, 2013-05, Vol.123 (5), p.2024-2036

2013

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Negative regulation of TLR signaling in myeloid cells-implications for autoimmune diseases

Immunological reviews, 2016-01, Vol.269 (1), p.212-227

2016

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FOXP3 and the regulation of Treg/Th17 differentiation

Microbes and infection, 2009-04, Vol.11 (5), p.594-598

2009

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B cell IFN-γ receptor signaling promotes autoimmune germinal centers via cell-intrinsic induction of BCL-6

The Journal of experimental medicine, 2016-05, Vol.213 (5), p.733-750

2016

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Gene editing to induce FOXP3 expression in human CD4 + T cells leads to a stable regulatory phenotype and function

Science translational medicine, 2020-06, Vol.12 (546)

2020

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Translational immunology: Applying fundamental discoveries to human health and autoimmune diseases

Immunotherapy: Building a bridge to a cure for type 1 diabetes

Rheumatoid arthritis and the mucosal origins hypothesis: protection turns to destruction

HLA autoimmune risk alleles restrict the hypervariable region of T cell receptors

B cell-derived IL-6 initiates spontaneous germinal center formation during systemic autoimmunity

Down syndrome: insights into autoimmune mechanisms

CD4+FOXP3+ T regulatory cells in human autoimmunity: more than a numbers game

IL-6: a cytokine at the crossroads of autoimmunity

Genetic basis of defects in immune tolerance underlying the development of autoimmunity

Immune-related adverse events after immune check point inhibitors: Understanding the intersection with autoimmunity

Low-dose interleukin-2 fosters a dose-dependent regulatory T cell tuned milieu in T1D patients

SARS-CoV-2 mRNA vaccines decouple anti-viral immunity from humoral autoimmunity

The role of PTPN22 risk variant in the development of autoimmunity: finding common ground between mouse and human

Type 1 diabetes immunotherapy using polyclonal regulatory T cells

The Effector T Cells of Diabetic Subjects Are Resistant to Regulation via CD4+FOXP3+ Regulatory T Cells

Th17 cells: from gut homeostasis to CNS pathogenesis

Complement receptor 2/CD21− human naive B cells contain mostly autoreactive unresponsive clones

Clinical and experimental treatment of type 1 diabetes

Clinical and experimental treatment of type 1 diabetes: Perspectives on immunopathology and Clinical and experimental treatment of type 1 diabetes

The dynamic epigenetic regulation of the inactive X chromosome in healthy human B cells is dysregulated in lupus patients

A disease-associated PTPN22 variant promotes systemic autoimmunity in murine models

Negative regulation of TLR signaling in myeloid cells-implications for autoimmune diseases

FOXP3 and the regulation of Treg/Th17 differentiation

B cell IFN-γ receptor signaling promotes autoimmune germinal centers via cell-intrinsic induction of BCL-6

Gene editing to induce FOXP3 expression in human CD4 + T cells leads to a stable regulatory phenotype and function

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