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Clusterin in Alzheimer's Disease: Mechanisms, Genetics, and Lessons From Other Pathologies

Frontiers in neuroscience, 2019-02, Vol.13, p.164-164

2019

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Cross-Regulation between an Alternative Splicing Activator and a Transcription Repressor Controls Neurogenesis

Molecular cell, 2011-09, Vol.43 (5), p.843-850

2011

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Ascl1 Coordinately Regulates Gene Expression and the Chromatin Landscape during Neurogenesis

Cell reports (Cambridge), 2015-03, Vol.10 (9), p.1544-1556

2015

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A microRNA-based gene dysregulation pathway in Huntington's disease

Neurobiology of disease, 2008-03, Vol.29 (3), p.438-445

2008

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HDAC inhibitors attenuate the development of hypersensitivity in models of neuropathic pain

Pain (Amsterdam), 2013-09, Vol.154 (9), p.1668-1679

2013

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The role of REST in transcriptional and epigenetic dysregulation in Huntington's disease

Neurobiology of disease, 2010-07, Vol.39 (1), p.28-39

2010

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Glycosylated clusterin species facilitate Aβ toxicity in human neurons

Scientific reports, 2022-11, Vol.12 (1), p.18639-16, Article 18639

2022

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Plasma Proteomic Biomarkers Relating to Alzheimer’s Disease: A Meta-Analysis Based on Our Own Studies

Frontiers in aging neuroscience, 2021-07, Vol.13, p.712545-712545

2021

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Transcriptional dysregulation of coding and non-coding genes in cellular models of Huntington's disease

Biochemical Society transactions, 2009-12, Vol.37 (Pt 6), p.1270-1275

2009

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Temporal transcriptional control of neural induction in human induced pluripotent stem cells

Frontiers in molecular neuroscience, 2023-05, Vol.16, p.1139287-1139287

2023

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Genome-Wide Analysis of Repressor Element 1 Silencing Transcription Factor/Neuron-Restrictive Silencing Factor (REST/NRSF) Target Genes

Proceedings of the National Academy of Sciences - PNAS, 2004-07, Vol.101 (28), p.10458-10463

2004

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REST regulates distinct transcriptional networks in embryonic and neural stem cells

PLoS biology, 2008-10, Vol.6 (10), p.e256-e256

2008

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Repressor element 1-silencing transcription factor deficiency yields profound hearing loss through Kv7.4 channel upsurge in auditory neurons and hair cells

eLife, 2022-09, Vol.11

2022

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Predicting AT(N) pathologies in Alzheimer's disease from blood-based proteomic data using neural networks

Frontiers in aging neuroscience, 2022-11, Vol.14, p.1040001-1040001

2022

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Prediction of Chromatin Accessibility in Gene-Regulatory Regions from Transcriptomics Data

Scientific reports, 2017-07, Vol.7 (1), p.4660-10, Article 4660

2017

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Binding of the repressor complex REST‐mSIN3b by small molecules restores neuronal gene transcription in Huntington's disease models

Journal of neurochemistry, 2013-10, Vol.127 (1), p.22-35

2013

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RE1 silencing transcription factor/neuron-restrictive silencing factor regulates expansion of adult mouse subventricular zone-derived neural stem/progenitor cells in vitro

Journal of neuroscience research, 2015-08, Vol.93 (8), p.1203-1214

2015

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BRG1 Chromatin Remodeling Activity Is Required for Efficient Chromatin Binding by Repressor Element 1-silencing Transcription Factor (REST) and Facilitates REST-mediated Repression

The Journal of biological chemistry, 2006-12, Vol.281 (51), p.38974-38980

2006

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A Role for RE‐1‐Silencing Transcription Factor in Embryonic Stem Cells Cardiac Lineage Specification

Stem cells (Dayton, Ohio), 2016-04, Vol.34 (4), p.860-872

2016

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Downregulated REST Transcription Factor Is a Switch Enabling Critical Potassium Channel Expression and Cell Proliferation

Molecular cell, 2005-10, Vol.20 (1), p.45-52

2005

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High Blood Pressure and Risk of Dementia: A Two-Sample Mendelian Randomization Study in the UK Biobank

Biological psychiatry (1969), 2021-04, Vol.89 (8), p.817-824

2021

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Involvement of P2X7 receptors in the regulation of neurotransmitter release in the rat hippocampus

Journal of neurochemistry, 2002-06, Vol.81 (6), p.1196-1211

2002

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Convergent molecular defects underpin diverse neurodegenerative diseases

Journal of neurology, neurosurgery and psychiatry, 2018-09, Vol.89 (9), p.962-969

2018

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Rest-mediated regulation of extracellular matrix is crucial for neural development

PloS one, 2008-11, Vol.3 (11), p.e3656-e3656

2008

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MiR‐375 is Essential for Human Spinal Motor Neuron Development and May Be Involved in Motor Neuron Degeneration

Stem cells (Dayton, Ohio), 2016-01, Vol.34 (1), p.124-134

2016

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Clusterin in Alzheimer's Disease: Mechanisms, Genetics, and Lessons From Other Pathologies

Cross-Regulation between an Alternative Splicing Activator and a Transcription Repressor Controls Neurogenesis

Ascl1 Coordinately Regulates Gene Expression and the Chromatin Landscape during Neurogenesis

A microRNA-based gene dysregulation pathway in Huntington's disease

HDAC inhibitors attenuate the development of hypersensitivity in models of neuropathic pain

The role of REST in transcriptional and epigenetic dysregulation in Huntington's disease

Glycosylated clusterin species facilitate Aβ toxicity in human neurons

Plasma Proteomic Biomarkers Relating to Alzheimer’s Disease: A Meta-Analysis Based on Our Own Studies

Transcriptional dysregulation of coding and non-coding genes in cellular models of Huntington's disease

Temporal transcriptional control of neural induction in human induced pluripotent stem cells

Genome-Wide Analysis of Repressor Element 1 Silencing Transcription Factor/Neuron-Restrictive Silencing Factor (REST/NRSF) Target Genes

REST regulates distinct transcriptional networks in embryonic and neural stem cells

Repressor element 1-silencing transcription factor deficiency yields profound hearing loss through Kv7.4 channel upsurge in auditory neurons and hair cells

Predicting AT(N) pathologies in Alzheimer's disease from blood-based proteomic data using neural networks

Prediction of Chromatin Accessibility in Gene-Regulatory Regions from Transcriptomics Data

Binding of the repressor complex REST‐mSIN3b by small molecules restores neuronal gene transcription in Huntington's disease models

RE1 silencing transcription factor/neuron-restrictive silencing factor regulates expansion of adult mouse subventricular zone-derived neural stem/progenitor cells in vitro

BRG1 Chromatin Remodeling Activity Is Required for Efficient Chromatin Binding by Repressor Element 1-silencing Transcription Factor (REST) and Facilitates REST-mediated Repression

A Role for RE‐1‐Silencing Transcription Factor in Embryonic Stem Cells Cardiac Lineage Specification

Downregulated REST Transcription Factor Is a Switch Enabling Critical Potassium Channel Expression and Cell Proliferation

High Blood Pressure and Risk of Dementia: A Two-Sample Mendelian Randomization Study in the UK Biobank

Involvement of P2X7 receptors in the regulation of neurotransmitter release in the rat hippocampus

Convergent molecular defects underpin diverse neurodegenerative diseases

Rest-mediated regulation of extracellular matrix is crucial for neural development

MiR‐375 is Essential for Human Spinal Motor Neuron Development and May Be Involved in Motor Neuron Degeneration

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