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Vaginal Film Drug Delivery of the Pyrimidinedione IQP-0528 for the Prevention of HIV Infection

Pharmaceutical research, 2012-07, Vol.29 (7), p.1897-1907

2012

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Novel 5'-Norcarbocyclic Pyrimidine Derivatives as Antibacterial Agents

Molecules (Basel, Switzerland), 2018-11, Vol.23 (12), p.3069

2018

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Investigation of 5'-Norcarbocyclic Nucleoside Analogues as Antiprotozoal and Antibacterial Agents

Molecules (Basel, Switzerland), 2019-09, Vol.24 (19), p.3433

2019

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In vitro and ex vivo evaluations on transdermal delivery of the HIV inhibitor IQP-0410

PloS one, 2013-09, Vol.8 (9), p.e75306

2013

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Lactobacillus proteins are associated with the bactericidal activity against E. coli of female genital tract secretions

PloS one, 2012-11, Vol.7 (11), p.e49506-e49506

2012

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Current Concepts for the IND-Directed Development of Microbicide Products to Prevent the Sexual Transmission of HIV

Current topics in medicinal chemistry, 2016-01, Vol.16 (10), p.1118-1134

2016

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Engineering soya bean seeds as a scalable platform to produce cyanovirin‐N, a non‐ARV microbicide against HIV

Plant biotechnology journal, 2015-09, Vol.13 (7), p.884-892

2015

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An algorithm for the preclinical development of anti-HIV topical microbicides

Current HIV research, 2012-01, Vol.10 (1), p.97-104

2012

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Examining the Safety, Pharmacokinetics, and Pharmacodynamics of a Rectally Administered IQP-0528 Gel for HIV Pre-Exposure Prophylaxis: A First-In-Human Study

AIDS research and human retroviruses, 2021-06, Vol.37 (6), p.444-452

2021

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Designing Dual Compartment HIV Prevention Products: Women's Sensory Perceptions and Experiences of Suppositories for Rectal and Vaginal Use

AIDS research and human retroviruses, 2022-07, Vol.38 (7), p.601-610

2022

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The Role of Volume in the Perceptibility of Topical Vaginal Formulations: User Sensory Perceptions and Experiences of Heterosexual Couples During Vaginal Sex

AIDS research and human retroviruses, 2020-12, Vol.36 (12), p.1059-1070

2020

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An Intravaginal Ring for the Simultaneous Delivery of an HIV-1 Maturation Inhibitor and Reverse-Transcriptase Inhibitor for Prophylaxis of HIV Transmission

Journal of pharmaceutical sciences, 2015-10, Vol.104 (10), p.3426-3439

2015

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Pharmacokinetic and Pharmacodynamic Evaluation following Vaginal Application of IQB3002, a Dual-Chamber Microbicide Gel Containing the Nonnucleoside Reverse Transcriptase Inhibitor IQP-0528 in Rhesus Macaques

Antimicrobial agents and chemotherapy, 2016-03, Vol.60 (3), p.1393-1400

2016

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Lubricant Provides Poor Rectal Mucosal HIV Coverage

AIDS research and human retroviruses, 2017-08, Vol.33 (8), p.784-787

2017

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Safety and efficacy of tenofovir/IQP-0528 combination gels – A dual compartment microbicide for HIV-1 prevention

Antiviral research, 2012-11, Vol.96 (2), p.221-225

2012

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The rational design and development of a dual chamber vaginal/rectal microbicide gel formulation for HIV prevention

Antiviral research, 2015-08, Vol.120, p.153-164

2015

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Synthesis and anti-HIV activities of symmetrical dicarboxylate esters of dinucleoside reverse transcriptase inhibitors

Bioorganic & medicinal chemistry letters, 2012-09, Vol.22 (17), p.5451-5454

2012

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Synthesis and biological evaluation of 5′-O-dicarboxylic fatty acyl monoester derivatives of anti-HIV nucleoside reverse transcriptase inhibitors

Tetrahedron letters, 2014-03, Vol.55 (12), p.1983-1986

2014

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Factors Important to the Prioritization and Development of Successful Topical Microbicides for HIV-1

Molecular Biology International, 2012-01, Vol.2012 (2012), p.263-274

2012

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Novel preclinical models of topical PrEP pharmacodynamics provide rationale for combination of drugs with complementary properties

Retrovirology, 2013-10, Vol.10 (1), p.113-113, Article 113

2013

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Effects of gel volume on pharmacokinetics for vaginal and rectal applications of combination DuoGel-IQB4012, a dual chamber-dual drug HIV microbicide gel, in pigtailed macaques

Drug delivery and translational research, 2018-10, Vol.8 (5), p.1180-1190

2018

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Carbocyclodipeptides as modified nucleosides: synthesis and anti-HIV activities

Canadian journal of chemistry, 2014-12, Vol.92 (12), p.1145-1149

2014

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IND-directed Pharmacology and Toxicology of IQP-0528, a Novel HIV-1 Topical Microbicide

AIDS research and human retroviruses, 2014-10, Vol.30 (S1), p.A261-A261

2014

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HIV-1 Shows Increased Sensitivity to Griffithsin Derivatives

AIDS research and human retroviruses, 2014-10, Vol.30 (S1), p.A203-A203

2014

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Use of the ICCA to Predict Dosing of HIV Microbicide Products to Achieve Virus Sterilization in Target Tissue

AIDS research and human retroviruses, 2014-10, Vol.30 (S1), p.A156-A156

2014

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Vaginal Film Drug Delivery of the Pyrimidinedione IQP-0528 for the Prevention of HIV Infection

Novel 5'-Norcarbocyclic Pyrimidine Derivatives as Antibacterial Agents

Investigation of 5'-Norcarbocyclic Nucleoside Analogues as Antiprotozoal and Antibacterial Agents

In vitro and ex vivo evaluations on transdermal delivery of the HIV inhibitor IQP-0410

Lactobacillus proteins are associated with the bactericidal activity against E. coli of female genital tract secretions

Current Concepts for the IND-Directed Development of Microbicide Products to Prevent the Sexual Transmission of HIV

Engineering soya bean seeds as a scalable platform to produce cyanovirin‐N, a non‐ARV microbicide against HIV

An algorithm for the preclinical development of anti-HIV topical microbicides

Examining the Safety, Pharmacokinetics, and Pharmacodynamics of a Rectally Administered IQP-0528 Gel for HIV Pre-Exposure Prophylaxis: A First-In-Human Study

Designing Dual Compartment HIV Prevention Products: Women's Sensory Perceptions and Experiences of Suppositories for Rectal and Vaginal Use

The Role of Volume in the Perceptibility of Topical Vaginal Formulations: User Sensory Perceptions and Experiences of Heterosexual Couples During Vaginal Sex

An Intravaginal Ring for the Simultaneous Delivery of an HIV-1 Maturation Inhibitor and Reverse-Transcriptase Inhibitor for Prophylaxis of HIV Transmission

Pharmacokinetic and Pharmacodynamic Evaluation following Vaginal Application of IQB3002, a Dual-Chamber Microbicide Gel Containing the Nonnucleoside Reverse Transcriptase Inhibitor IQP-0528 in Rhesus Macaques

Lubricant Provides Poor Rectal Mucosal HIV Coverage

Safety and efficacy of tenofovir/IQP-0528 combination gels – A dual compartment microbicide for HIV-1 prevention

The rational design and development of a dual chamber vaginal/rectal microbicide gel formulation for HIV prevention

Synthesis and anti-HIV activities of symmetrical dicarboxylate esters of dinucleoside reverse transcriptase inhibitors

Synthesis and biological evaluation of 5′-O-dicarboxylic fatty acyl monoester derivatives of anti-HIV nucleoside reverse transcriptase inhibitors

Factors Important to the Prioritization and Development of Successful Topical Microbicides for HIV-1

Novel preclinical models of topical PrEP pharmacodynamics provide rationale for combination of drugs with complementary properties

Effects of gel volume on pharmacokinetics for vaginal and rectal applications of combination DuoGel-IQB4012, a dual chamber-dual drug HIV microbicide gel, in pigtailed macaques

Carbocyclodipeptides as modified nucleosides: synthesis and anti-HIV activities

IND-directed Pharmacology and Toxicology of IQP-0528, a Novel HIV-1 Topical Microbicide

HIV-1 Shows Increased Sensitivity to Griffithsin Derivatives

Use of the ICCA to Predict Dosing of HIV Microbicide Products to Achieve Virus Sterilization in Target Tissue

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