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Structural conservation of insulin/IGF signalling axis at the insulin receptors level in Drosophila and humans

Nature communications, 2023-10, Vol.14 (1), p.6271-6271, Article 6271

2023

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Structures of insect Imp-L2 suggest an alternative strategy for regulating the bioavailability of insulin-like hormones

Nature communications, 2018-09, Vol.9 (1), p.3860-12, Article 3860

2018

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Insulin and Insulin-like Growth Factor II Differentially Regulate Endocytic Sorting and Stability of Insulin Receptor Isoform A

The Journal of biological chemistry, 2012-03, Vol.287 (14), p.11422-11436

2012

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Structural and functional study of the GlnB22-insulin mutant responsible for maturity-onset diabetes of the young

PloS one, 2014-11, Vol.9 (11), p.e112883-e112883

2014

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Structural characterization of human heparanase reveals insights into substrate recognition

Nature structural & molecular biology, 2015-12, Vol.22 (12), p.1016-1022

2015

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Thermodynamic and structural investigation of the specific SDS binding of humicola insolens cutinase

Protein science, 2014-08, Vol.23 (8), p.1023-1035

2014

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Cross-Linking/Mass Spectrometry Uncovers Details of Insulin-Like Growth Factor Interaction With Insect Insulin Binding Protein Imp-L2

Frontiers in endocrinology (Lausanne), 2019-10, Vol.10, p.695-695

2019

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Implications for the active form of human insulin based on the structural convergence of highly active hormone analogues

Proceedings of the National Academy of Sciences - PNAS, 2010-02, Vol.107 (5), p.1966-1970

2010

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How insulin engages its primary binding site on the insulin receptor

Nature (London), 2013-01, Vol.493 (7431), p.241-245

2013

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Can Arginine Inhibit Insulin Aggregation? A Combined Protein Crystallography, Capillary Electrophoresis, and Molecular Simulation Study

The journal of physical chemistry. B, 2018-11, Vol.122 (44), p.10069-10076

2018

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The Crystal Structure of the AAA Domain of the ATP-Dependent Protease FtsH of Escherichia coli at 1.5 Å Resolution

Structure (London), 2002-08, Vol.10 (8), p.1073-1083

2002

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The Crystal Structure of Gankyrin, an Oncoprotein Found in Complexes with Cyclin-dependent Kinase 4, a 19 S Proteasomal ATPase Regulator, and the Tumor Suppressors Rb and p53

The Journal of biological chemistry, 2004-01, Vol.279 (2), p.1541-1545

2004

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Structure of Human Factor VIIa and Its Implications for the Triggering of Blood Coagulation

Proceedings of the National Academy of Sciences - PNAS, 1999-08, Vol.96 (16), p.8925-8930

1999

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Structural and biochemical characterization of a mitochondrial peroxiredoxin from Plasmodium falciparum

Molecular microbiology, 2006-08, Vol.61 (4), p.948-959

2006

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Insulin-like Growth Factor 1 Analogs Clicked in the C Domain: Chemical Synthesis and Biological Activities

Journal of medicinal chemistry, 2017-12, Vol.60 (24), p.10105-10117

2017

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Computational and structural evidence for neurotransmitter-mediated modulation of the oligomeric states of human insulin in storage granules

The Journal of biological chemistry, 2017-05, Vol.292 (20), p.8342-8355

2017

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Structural Origins of the Functional Divergence of Human Insulin-Like Growth Factor-I and Insulin

Biochemistry (Easton), 2002-07, Vol.41 (30), p.9389-9397

2002

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Converting Insulin-like Growth Factors 1 and 2 into High-Affinity Ligands for Insulin Receptor Isoform A by the Introduction of an Evolutionarily Divergent Mutation

Biochemistry (Easton), 2018-04, Vol.57 (16), p.2373-2382

2018

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Recombinant polymorphic membrane protein D in combination with a novel, second-generation lipid adjuvant protects against intra-vaginal Chlamydia trachomatis infection in mice

Vaccine, 2016-07, Vol.34 (35), p.4123-4131

2016

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Catalysis at the interface: the anatomy of a conformational change in a triglyceride lipase

Biochemistry (Easton), 1992-02, Vol.31 (5), p.1532-1541

1992

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Insulin–Insulin-like Growth Factors Hybrids as Molecular Probes of Hormone:Receptor Binding Specificity

Biochemistry (Easton), 2016-05, Vol.55 (21), p.2903-2913

2016

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N-Myristoyltransferase from Leishmania donovani: Structural and Functional Characterisation of a Potential Drug Target for Visceral Leishmaniasis

Journal of molecular biology, 2010-03, Vol.396 (4), p.985-999

2010

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Insight into the Structural and Biological Relevance of the T/R Transition of the N‑Terminus of the B‑Chain in Human Insulin

Biochemistry (Easton), 2014-06, Vol.53 (21), p.3392-3402

2014

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Structural Integrity of the B24 Site in Human Insulin Is Important for Hormone Functionality

The Journal of biological chemistry, 2013-04, Vol.288 (15), p.10230-10240

2013

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Molecular basis of agonism and antagonism in the oestrogen receptor

Nature (London), 1997-10, Vol.389 (6652), p.753-758

1997

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Structural conservation of insulin/IGF signalling axis at the insulin receptors level in Drosophila and humans

Structures of insect Imp-L2 suggest an alternative strategy for regulating the bioavailability of insulin-like hormones

Insulin and Insulin-like Growth Factor II Differentially Regulate Endocytic Sorting and Stability of Insulin Receptor Isoform A

Structural and functional study of the GlnB22-insulin mutant responsible for maturity-onset diabetes of the young

Structural characterization of human heparanase reveals insights into substrate recognition

Thermodynamic and structural investigation of the specific SDS binding of humicola insolens cutinase

Cross-Linking/Mass Spectrometry Uncovers Details of Insulin-Like Growth Factor Interaction With Insect Insulin Binding Protein Imp-L2

Implications for the active form of human insulin based on the structural convergence of highly active hormone analogues

How insulin engages its primary binding site on the insulin receptor

Can Arginine Inhibit Insulin Aggregation? A Combined Protein Crystallography, Capillary Electrophoresis, and Molecular Simulation Study

The Crystal Structure of the AAA Domain of the ATP-Dependent Protease FtsH of Escherichia coli at 1.5 Å Resolution

The Crystal Structure of Gankyrin, an Oncoprotein Found in Complexes with Cyclin-dependent Kinase 4, a 19 S Proteasomal ATPase Regulator, and the Tumor Suppressors Rb and p53

Structure of Human Factor VIIa and Its Implications for the Triggering of Blood Coagulation

Structural and biochemical characterization of a mitochondrial peroxiredoxin from Plasmodium falciparum

Insulin-like Growth Factor 1 Analogs Clicked in the C Domain: Chemical Synthesis and Biological Activities

Computational and structural evidence for neurotransmitter-mediated modulation of the oligomeric states of human insulin in storage granules

Structural Origins of the Functional Divergence of Human Insulin-Like Growth Factor-I and Insulin

Converting Insulin-like Growth Factors 1 and 2 into High-Affinity Ligands for Insulin Receptor Isoform A by the Introduction of an Evolutionarily Divergent Mutation

Recombinant polymorphic membrane protein D in combination with a novel, second-generation lipid adjuvant protects against intra-vaginal Chlamydia trachomatis infection in mice

Catalysis at the interface: the anatomy of a conformational change in a triglyceride lipase

Insulin–Insulin-like Growth Factors Hybrids as Molecular Probes of Hormone:Receptor Binding Specificity

N-Myristoyltransferase from Leishmania donovani: Structural and Functional Characterisation of a Potential Drug Target for Visceral Leishmaniasis

Insight into the Structural and Biological Relevance of the T/R Transition of the N‑Terminus of the B‑Chain in Human Insulin

Structural Integrity of the B24 Site in Human Insulin Is Important for Hormone Functionality

Molecular basis of agonism and antagonism in the oestrogen receptor

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