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A molecular switch regulating transcriptional repression and activation of PPARγ

Nature communications, 2020-02, Vol.11 (1), p.956-956, Article 956

2020

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A structural mechanism for directing corepressor-selective inverse agonism of PPARγ

Nature communications, 2018-11, Vol.9 (1), p.4687-14, Article 4687

2018

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Cooperative cobinding of synthetic and natural ligands to the nuclear receptor PPARγ

eLife, 2018-12, Vol.7 (12, 2018)

2018

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Photoactivation of the BLUF Protein PixD Probed by the Site-Specific Incorporation of Fluorotyrosine Residues

Journal of the American Chemical Society, 2017-10, Vol.139 (41), p.14638-14648

2017

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Proteins in Action: Femtosecond to Millisecond Structural Dynamics of a Photoactive Flavoprotein

Journal of the American Chemical Society, 2013-10, Vol.135 (43), p.16168-16174

2013

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Identification of a Binding Site for Unsaturated Fatty Acids in the Orphan Nuclear Receptor Nurr1

ACS chemical biology, 2016-07, Vol.11 (7), p.1795-1799

2016

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Complete Proton Transfer Cycle in GFP and Its T203V and S205V Mutants

Angewandte Chemie (International ed.), 2015-08, Vol.54 (32), p.9303-9307

International ed. in English, 2015

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Photoexcitation of the Blue Light Using FAD Photoreceptor AppA Results in Ultrafast Changes to the Protein Matrix

Journal of the American Chemical Society, 2011-10, Vol.133 (42), p.16893-16900

2011

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Mechanism of the AppABLUF Photocycle Probed by Site-Specific Incorporation of Fluorotyrosine Residues: Effect of the Y21 pKa on the Forward and Reverse Ground-State Reactions

Journal of the American Chemical Society, 2016-01, Vol.138 (3), p.926-935

2016

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Protein Photochromism Observed by Ultrafast Vibrational Spectroscopy

The journal of physical chemistry. B, 2013-10, Vol.117 (40), p.11954-11959

2013

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Excited State Structure and Dynamics of the Neutral and Anionic Flavin Radical Revealed by Ultrafast Transient Mid-IR to Visible Spectroscopy

The journal of physical chemistry. B, 2012-05, Vol.116 (20), p.5810-5818

2012

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Ultrafast Structural Dynamics of BlsA, a Photoreceptor from the Pathogenic Bacterium Acinetobacter baumannii

The journal of physical chemistry letters, 2014-01, Vol.5 (1), p.220-224

2014

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Electron transfer quenching in light adapted and mutant forms of the AppA BLUF domain

Faraday discussions, 2015-01, Vol.177, p.293-311

2015

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Vibrational Assignment of the Ultrafast Infrared Spectrum of the Photoactivatable Flavoprotein AppA

The journal of physical chemistry. B, 2012-09, Vol.116 (35), p.10722-10729

2012

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Ultrafast Infrared Spectroscopy of an Isotope-Labeled Photoactivatable Flavoprotein

Biochemistry (Easton), 2011-03, Vol.50 (8), p.1321-1328

2011

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Structural mechanism of corepressor‐selective inverse agonism of the nuclear receptor PPARγ

The FASEB journal, 2019-04, Vol.33 (S1), p.779.22-779.22

2019

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The Pompano Boys: How Florida's "Little Scottsboro Case" Led to a Revolution in Criminal Justice

Brust, Richard

2022

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A Comparison of Hybridization between Mottled Ducks (Anas fulvigula)and Mallards (A. platyrhynchos) in Florida and South Carolina using Microsatellite DNA Analysis

Conservation genetics, 2005-05, Vol.6 (3), p.445-453

2005

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Quantitative structural assessment of graded receptor agonism

Proceedings of the National Academy of Sciences - PNAS, 2019-10, Vol.116 (44), p.22179-22188

2019

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Structural Basis of Altered Potency and Efficacy Displayed by a Major in Vivo Metabolite of the Antidiabetic PPARγ Drug Pioglitazone

Journal of medicinal chemistry, 2019-02, Vol.62 (4), p.2008-2023

2019

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Modification of the Orthosteric PPARγ Covalent Antagonist Scaffold Yields an Improved Dual-Site Allosteric Inhibitor

ACS chemical biology, 2017-04, Vol.12 (4), p.969-978

2017

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Development and Characterization of Dual‐Site PPARγ Antagonists

The FASEB journal, 2016-04, Vol.30 (S1)

2016

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Structural basis of altered potency and efficacy displayed by a major in vivo metabolite of the anti-diabetic PPARγ drug pioglitazone

Journal of medicinal chemistry, 2019-02, Vol.62 (4), p.2008-2023

2019

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Synergistic Regulation of Coregulator/Nuclear Receptor Interaction by Ligand and DNA

Structure (London), 2017-10, Vol.25 (10), p.1506-1518.e4

2017

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Chemical Crosslinking Mass Spectrometry Reveals the Conformational Landscape of the Activation Helix of PPARγ; a Model for Ligand-Dependent Antagonism

Structure (London), 2018-11, Vol.26 (11), p.1431-1439.e6

2018

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A molecular switch regulating transcriptional repression and activation of PPARγ

A structural mechanism for directing corepressor-selective inverse agonism of PPARγ

Cooperative cobinding of synthetic and natural ligands to the nuclear receptor PPARγ

Photoactivation of the BLUF Protein PixD Probed by the Site-Specific Incorporation of Fluorotyrosine Residues

Proteins in Action: Femtosecond to Millisecond Structural Dynamics of a Photoactive Flavoprotein

Identification of a Binding Site for Unsaturated Fatty Acids in the Orphan Nuclear Receptor Nurr1

Complete Proton Transfer Cycle in GFP and Its T203V and S205V Mutants

Photoexcitation of the Blue Light Using FAD Photoreceptor AppA Results in Ultrafast Changes to the Protein Matrix

Mechanism of the AppABLUF Photocycle Probed by Site-Specific Incorporation of Fluorotyrosine Residues: Effect of the Y21 pKa on the Forward and Reverse Ground-State Reactions

Protein Photochromism Observed by Ultrafast Vibrational Spectroscopy

Excited State Structure and Dynamics of the Neutral and Anionic Flavin Radical Revealed by Ultrafast Transient Mid-IR to Visible Spectroscopy

Ultrafast Structural Dynamics of BlsA, a Photoreceptor from the Pathogenic Bacterium Acinetobacter baumannii

Electron transfer quenching in light adapted and mutant forms of the AppA BLUF domain

Vibrational Assignment of the Ultrafast Infrared Spectrum of the Photoactivatable Flavoprotein AppA

Ultrafast Infrared Spectroscopy of an Isotope-Labeled Photoactivatable Flavoprotein

Structural mechanism of corepressor‐selective inverse agonism of the nuclear receptor PPARγ

The Pompano Boys: How Florida's "Little Scottsboro Case" Led to a Revolution in Criminal Justice

A Comparison of Hybridization between Mottled Ducks (Anas fulvigula)and Mallards (A. platyrhynchos) in Florida and South Carolina using Microsatellite DNA Analysis

Quantitative structural assessment of graded receptor agonism

Structural Basis of Altered Potency and Efficacy Displayed by a Major in Vivo Metabolite of the Antidiabetic PPARγ Drug Pioglitazone

Modification of the Orthosteric PPARγ Covalent Antagonist Scaffold Yields an Improved Dual-Site Allosteric Inhibitor

Development and Characterization of Dual‐Site PPARγ Antagonists

Structural basis of altered potency and efficacy displayed by a major in vivo metabolite of the anti-diabetic PPARγ drug pioglitazone

Synergistic Regulation of Coregulator/Nuclear Receptor Interaction by Ligand and DNA

Chemical Crosslinking Mass Spectrometry Reveals the Conformational Landscape of the Activation Helix of PPARγ; a Model for Ligand-Dependent Antagonism

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