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De novo Lipogenesis Protects Cancer Cells from Free Radicals and Chemotherapeutics by Promoting Membrane Lipid Saturation

Cancer research (Chicago, Ill.), 2010-10, Vol.70 (20), p.8117-8126

2010

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Chemical inhibition of acetyl-CoA carboxylase induces growth arrest and cytotoxicity selectively in cancer cells

Cancer research (Chicago, Ill.), 2007-09, Vol.67 (17), p.8180-8187

2007

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Induction of Cancer Cell Apoptosis by Flavonoids Is Associated with Their Ability to Inhibit Fatty Acid Synthase Activity

The Journal of biological chemistry, 2005-02, Vol.280 (7), p.5636-5645

2005

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Squalene Synthase, a Determinant of Raft-associated Cholesterol and Modulator of Cancer Cell Proliferation

The Journal of biological chemistry, 2007-06, Vol.282 (26), p.18777-18785

2007

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Mimicry of a cellular low energy status blocks tumor cell anabolism and suppresses the malignant phenotype

Cancer research (Chicago, Ill.), 2005-03, Vol.65 (6), p.2441-2448

2005

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Impaired myocardial angiogenesis and ischemic cardiomyopathy in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188

Nature medicine, 1999-05, Vol.5 (5), p.495-502

1999

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Aberrant Activation of Fatty Acid Synthesis Suppresses Primary Cilium Formation and Distorts Tissue Development

Cancer research (Chicago, Ill.), 2010-11, Vol.70 (22), p.9453-9462

2010

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A Novel Role for Vascular Endothelial Growth Factor as an Autocrine Survival Factor for Embryonic Stem Cells during Hypoxia

The Journal of biological chemistry, 2005-02, Vol.280 (5), p.3493-3499

2005

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Increased lipogenesis in cancer cells: new players, novel targets

Current opinion in clinical nutrition and metabolic care, 2006-07, Vol.9 (4), p.358-365

2006

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Methotrexate enhances the antianabolic and antiproliferative effects of 5-aminoimidazole-4-carboxamide riboside

Molecular cancer therapeutics, 2006-09, Vol.5 (9), p.2211-2217

2006

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Loss of placental growth factor protects mice against vascular permeability in pathological conditions

Biochemical and biophysical research communications, 2002-07, Vol.295 (2), p.428-434

2002

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Rna interference-mediated silencing of the acetyl-CoA-carboxylase-α gene induces growth inhibition and apoptosis of prostate cancer cells

Cancer research (Chicago, Ill.), 2005-08, Vol.65 (15), p.6719-6725

2005

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Heterozygous deficiency of hypoxia-inducible factor–2α protects mice against pulmonary hypertension and right ventricular dysfunction during prolonged hypoxia

The Journal of clinical investigation, 2003-05, Vol.111 (10), p.1519-1527

2003

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Loss of HIF-2α and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice

Nature medicine, 2002-07, Vol.8 (7), p.702-710

2002

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Loss of HIF-2[alpha] and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice

Nature medicine, 2002-07, Vol.8 (7), p.702

2002

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Heterozygous deficiency of hypoxia-inducible factor-2 alpha protects mice against pulmonary hypertension and right ventricular dysfunction during prolonged hypoxia

The Journal of clinical investigation, 2003-05, Vol.111 (10), p.1519-1527

2003

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Epigallocatechin‐3‐gallate is a potent natural inhibitor of fatty acid synthase in intact cells and selectively induces apoptosis in prostate cancer cells

International journal of cancer, 2003-10, Vol.106 (6), p.856-862

2003

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RNA interference-mediated silencing of the fatty acid synthase gene attenuates growth and induces morphological changes and apoptosis of LNCaP prostate cancer cells

Cancer research (Chicago, Ill.), 2003-07, Vol.63 (13), p.3799-3804

2003

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Cardia bifida, defective heart development and abnormal neural crest migration in embryos lacking hypoxia-inducible factor-1α

Cardiovascular research, 2003-12, Vol.60 (3), p.569-579

2003

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Heterozygous deficiency of hypoxia-inducible factor-2alpha protects mice against pulmonary hypertension and right ventricular dysfunction during prolonged hypoxia

The Journal of clinical investigation, 2003-05, Vol.111 (10), p.1519-1527

2003

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Genetic evidence for a tumor suppressor role of HIF-2α

Cancer cell, 2005-08, Vol.8 (2), p.131-141

2005

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Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

Nature (London), 1998-07, Vol.394 (6692), p.485-490

1998

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Fatty acid synthase drives the synthesis of phospholipids partitioning into detergent-resistant membrane microdomains

Biochemical and biophysical research communications, 2003-03, Vol.302 (4), p.898-903

2003

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Androgens, lipogenesis and prostate cancer

The Journal of steroid biochemistry and molecular biology, 2004-11, Vol.92 (4), p.273-279

2004

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De novo Lipogenesis Protects Cancer Cells from Free Radicals and Chemotherapeutics by Promoting Membrane Lipid Saturation

Chemical inhibition of acetyl-CoA carboxylase induces growth arrest and cytotoxicity selectively in cancer cells

Induction of Cancer Cell Apoptosis by Flavonoids Is Associated with Their Ability to Inhibit Fatty Acid Synthase Activity

Squalene Synthase, a Determinant of Raft-associated Cholesterol and Modulator of Cancer Cell Proliferation

Mimicry of a cellular low energy status blocks tumor cell anabolism and suppresses the malignant phenotype

Impaired myocardial angiogenesis and ischemic cardiomyopathy in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188

Aberrant Activation of Fatty Acid Synthesis Suppresses Primary Cilium Formation and Distorts Tissue Development

A Novel Role for Vascular Endothelial Growth Factor as an Autocrine Survival Factor for Embryonic Stem Cells during Hypoxia

Increased lipogenesis in cancer cells: new players, novel targets

Methotrexate enhances the antianabolic and antiproliferative effects of 5-aminoimidazole-4-carboxamide riboside

Loss of placental growth factor protects mice against vascular permeability in pathological conditions

Rna interference-mediated silencing of the acetyl-CoA-carboxylase-α gene induces growth inhibition and apoptosis of prostate cancer cells

Heterozygous deficiency of hypoxia-inducible factor–2α protects mice against pulmonary hypertension and right ventricular dysfunction during prolonged hypoxia

Loss of HIF-2α and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice

Loss of HIF-2[alpha] and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice

Heterozygous deficiency of hypoxia-inducible factor-2 alpha protects mice against pulmonary hypertension and right ventricular dysfunction during prolonged hypoxia

Epigallocatechin‐3‐gallate is a potent natural inhibitor of fatty acid synthase in intact cells and selectively induces apoptosis in prostate cancer cells

RNA interference-mediated silencing of the fatty acid synthase gene attenuates growth and induces morphological changes and apoptosis of LNCaP prostate cancer cells

Cardia bifida, defective heart development and abnormal neural crest migration in embryos lacking hypoxia-inducible factor-1α

Heterozygous deficiency of hypoxia-inducible factor-2alpha protects mice against pulmonary hypertension and right ventricular dysfunction during prolonged hypoxia

Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration

Genetic evidence for a tumor suppressor role of HIF-2α

Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

Fatty acid synthase drives the synthesis of phospholipids partitioning into detergent-resistant membrane microdomains

Androgens, lipogenesis and prostate cancer

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