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Safety and pharmacokinetics of SPR206 in subjects with varying degrees of renal impairment

Antimicrobial agents and chemotherapy, 2023-11, Vol.67 (11), p.e0050523-e0050523

2023

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Pharmacokinetics of SPR206 in Plasma, Pulmonary Epithelial Lining Fluid, and Alveolar Macrophages following Intravenous Administration to Healthy Adult Subjects

Antimicrobial agents and chemotherapy, 2023-07, Vol.67 (7), p.e0042623-e0042623

2023

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The economics of pediatric formulation development for off-patent drugs

Clinical therapeutics, 2008-11, Vol.30 (11), p.2133-2145

2008

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Pharmacokinetics and Safety of Single and Multiple Doses of ACHN-490 Injection Administered Intravenously in Healthy Subjects

Antimicrobial Agents and Chemotherapy, 2011-12, Vol.55 (12), p.5874-5880

2011

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Hematologic Effects of Linezolid: Summary of Clinical Experience

Antimicrobial Agents and Chemotherapy, 2002-08, Vol.46 (8), p.2723-2726

2002

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Lack of Evidence Associating Nephrotoxicity with Low-Dose Gentamicin for Staphylococcus aureus Bacteremia and Endocarditis

Clinical infectious diseases, 2009-09, Vol.49 (5), p.806-806

Bruss, Jon B.

2009

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Source Control Review in Clinical Trials of Anti-Infective Agents in Complicated Intra-Abdominal Infections

Clinical infectious diseases, 2013-06, Vol.56 (12), p.1765-1773

2013

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Randomized Comparison of Linezolid (PNU-100766) versus Oxacillin-Dicloxacillin for Treatment of Complicated Skin and Soft Tissue Infections

Antimicrobial Agents and Chemotherapy, 2000-12, Vol.44 (12), p.3408-3413

2000

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Linezolid versus vancomycin for treatment of resistant Gram-positive infections in children

The Pediatric infectious disease journal, 2003-08, Vol.22 (8), p.677-686

2003

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Telavancin in the Treatment of Concurrent Staphylococcus aureus Bacteremia: A Retrospective Analysis of ATLAS and ATTAIN Studies

Infectious diseases and therapy, 2017-09, Vol.6 (3), p.413-422

2017

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Linezolid versus vancomycin in the treatment of known or suspected resistant Gram-positive infections in neonates

The Pediatric infectious disease journal, 2003-09, Vol.22 (9 Suppl), p.S158-S163

2003

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A Double-Blind, Placebo-Controlled Trial of Oral Human Immunoglobulin for Gastrointestinal Dysfunction in Children with Autistic Disorder

Journal of autism and developmental disorders, 2009-05, Vol.39 (5), p.796-805

2009

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Safety and tolerability of linezolid in children

The Pediatric infectious disease journal, 2003-09, Vol.22 (9 Suppl), p.S193-S200

2003

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Linezolid for the treatment of methicillin-resistant Staphylococcus aureus infections in children

The Pediatric infectious disease journal, 2003-09, Vol.22 (9 Suppl), p.S178-S185

2003

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2130. Safety and Pharmacokinetics of SPR206 in Subjects with Varying Degrees of Renal Impairment

Open forum infectious diseases, 2023-11, Vol.10 (Supplement_2)

2023

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Single- and Multiple-Ascending-Dose Study of the Safety, Tolerability, and Pharmacokinetics of the Polymyxin Derivative SPR206

Antimicrobial agents and chemotherapy, 2021-09, Vol.65 (10)

2021

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Hematologic effects of linezolid in young children

The Pediatric infectious disease journal, 2003-09, Vol.22 (9 Suppl), p.S186-S192

2003

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Linezolid for the treatment of children with bacteremia or nosocomial pneumonia caused by resistant Gram-positive bacterial pathogens

The Pediatric infectious disease journal, 2003-09, Vol.22 (9 Suppl), p.S164-S171

2003

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Linezolid versus cefadroxil in the treatment of skin and skin structure infections in children

The Pediatric infectious disease journal, 2003-04, Vol.22 (4), p.315-322

2003

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Impact of ontogeny on linezolid disposition in neonates and infants

Clinical pharmacology and therapeutics, 2003-11, Vol.74 (5), p.413-422

2003

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Plasma and Intrapulmonary Concentrations of Tebipenem following Oral Administration of Tebipenem Pivoxil Hydrobromide to Healthy Adult Subjects

Antimicrobial agents and chemotherapy, 2022-07, Vol.66 (7), p.e0059022

2022

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Linezolid for the treatment of complicated skin and skin structure infections in children

The Pediatric infectious disease journal, 2003-09, Vol.22 (9 Suppl), p.S172-S177

2003

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Pharmacokinetics of Oral Tebipenem Pivoxil Hydrobromide in Subjects with Various Degrees of Renal Impairment

Antimicrobial agents and chemotherapy, 2022-05, Vol.66 (5), p.e0240721-e0240721

2022

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A severity score for complicated skin and soft tissue infections derived from phase III studies of linezolid

The American journal of surgery, 2003-04, Vol.185 (4), p.369-375

2003

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625. SPR206 Pharmacokinetics (PK) in Plasma, Epithelial Lining Fluid (ELF), and Alveolar Macrophages (AM) in Healthy Adult Subjects

Open forum infectious diseases, 2022-12, Vol.9 (Supplement_2)

2022

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Safety and pharmacokinetics of SPR206 in subjects with varying degrees of renal impairment

Pharmacokinetics of SPR206 in Plasma, Pulmonary Epithelial Lining Fluid, and Alveolar Macrophages following Intravenous Administration to Healthy Adult Subjects

The economics of pediatric formulation development for off-patent drugs

Pharmacokinetics and Safety of Single and Multiple Doses of ACHN-490 Injection Administered Intravenously in Healthy Subjects

Hematologic Effects of Linezolid: Summary of Clinical Experience

Lack of Evidence Associating Nephrotoxicity with Low-Dose Gentamicin for Staphylococcus aureus Bacteremia and Endocarditis

Source Control Review in Clinical Trials of Anti-Infective Agents in Complicated Intra-Abdominal Infections

Randomized Comparison of Linezolid (PNU-100766) versus Oxacillin-Dicloxacillin for Treatment of Complicated Skin and Soft Tissue Infections

Linezolid versus vancomycin for treatment of resistant Gram-positive infections in children

Telavancin in the Treatment of Concurrent Staphylococcus aureus Bacteremia: A Retrospective Analysis of ATLAS and ATTAIN Studies

Linezolid versus vancomycin in the treatment of known or suspected resistant Gram-positive infections in neonates

A Double-Blind, Placebo-Controlled Trial of Oral Human Immunoglobulin for Gastrointestinal Dysfunction in Children with Autistic Disorder

Safety and tolerability of linezolid in children

Linezolid for the treatment of methicillin-resistant Staphylococcus aureus infections in children

2130. Safety and Pharmacokinetics of SPR206 in Subjects with Varying Degrees of Renal Impairment

Single- and Multiple-Ascending-Dose Study of the Safety, Tolerability, and Pharmacokinetics of the Polymyxin Derivative SPR206

Hematologic effects of linezolid in young children

Linezolid for the treatment of children with bacteremia or nosocomial pneumonia caused by resistant Gram-positive bacterial pathogens

Linezolid versus cefadroxil in the treatment of skin and skin structure infections in children

Impact of ontogeny on linezolid disposition in neonates and infants

Plasma and Intrapulmonary Concentrations of Tebipenem following Oral Administration of Tebipenem Pivoxil Hydrobromide to Healthy Adult Subjects

Linezolid for the treatment of complicated skin and skin structure infections in children

Pharmacokinetics of Oral Tebipenem Pivoxil Hydrobromide in Subjects with Various Degrees of Renal Impairment

A severity score for complicated skin and soft tissue infections derived from phase III studies of linezolid

625. SPR206 Pharmacokinetics (PK) in Plasma, Epithelial Lining Fluid (ELF), and Alveolar Macrophages (AM) in Healthy Adult Subjects

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