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The therapeutic potential of inhibiting PPARγ phosphorylation to treat type 2 diabetes

The Journal of biological chemistry, 2021-09, Vol.297 (3), p.101030-101030, Article 101030

2021

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Review of the Structural and Dynamic Mechanisms of PPARγ Partial Agonism

PPAR Research, 2015-01, Vol.2015, p.816856-15

2015

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A comparison of the bacterial CYP51 cytochrome P450 enzymes from Mycobacterium marinum and Mycobacterium tuberculosis

The Journal of steroid biochemistry and molecular biology, 2022-07, Vol.221, p.106097-106097, Article 106097

2022

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Structural mechanism for signal transduction in RXR nuclear receptor heterodimers

Nature communications, 2015-08, Vol.6 (1), p.8013-8013, Article 8013

2015

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Expressing a moth abcc2 gene in transgenic Drosophila causes susceptibility to Bt Cry1Ac without requiring a cadherin-like protein receptor

Insect biochemistry and molecular biology, 2017-01, Vol.80, p.61-70

2017

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DNA binding alters coactivator interaction surfaces of the intact VDR-RXR complex

Nature structural & molecular biology, 2011-05, Vol.18 (5), p.556

2011

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Structure of the Mycobacterium tuberculosis d-Alanine:d-Alanine Ligase, a Target of the Antituberculosis Drug d-Cycloserine

Antimicrobial Agents and Chemotherapy, 2011-01, Vol.55 (1), p.291-301

2011

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Loss-of-function mutations in SIM1 contribute to obesity and Prader-Willi-like features

The Journal of clinical investigation, 2013-07, Vol.123 (7), p.3037-3041

2013

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HDX reveals the conformational dynamics of DNA sequence specific VDR co-activator interactions

Nature communications, 2017-10, Vol.8 (1), p.923-13, Article 923

2017

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Coupling of receptor conformation and ligand orientation determine graded activity

Nature chemical biology, 2010-11, Vol.6 (11), p.837

2010

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Targeting Unconventional Pathways in Pursuit of Novel Antifungals

Frontiers in molecular biosciences, 2021-01, Vol.7, p.621366

2021

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Biochemical and in silico characterization of glycosyltransferases from red sweet cherry (Prunus avium L.) reveals their broad specificity toward phenolic substrates

Food chemistry. Molecular sciences, 2024-07, Vol.8, p.100193-100193, Article 100193

2024

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Mycobacterium tuberculosis Dethiobiotin Synthetase Facilitates Nucleoside Triphosphate Promiscuity through Alternate Binding Modes

ACS catalysis, 2018-11, Vol.8 (11), p.10774-10783

2018

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Human variants in the neuronal basic helix-loop-helix/Per-Arnt-Sim (bHLH/PAS) transcription factor complex NPAS4/ARNT2 disrupt function

PloS one, 2014-01, Vol.9 (1), p.e85768-e85768

2014

Volltextzugriff (PDF)

JAK2 Alterations in Acute Lymphoblastic Leukemia: Molecular Insights for Superior Precision Medicine Strategies

Frontiers in cell and developmental biology, 2022-07, Vol.10, p.942053-942053

2022

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Acquired JAK2 mutations confer resistance to JAK inhibitors in cell models of acute lymphoblastic leukemia

NPJ precision oncology, 2021-08, Vol.5 (1), p.1-13, Article 75

2021

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PPARγ in Complex with an Antagonist and Inverse Agonist: a Tumble and Trap Mechanism of the Activation Helix

iScience, 2018-07, Vol.5, p.69-79

2018

Volltextzugriff (PDF)

Towards a High-Affinity Peptidomimetic Targeting Proliferating Cell Nuclear Antigen from Aspergillus fumigatus

Journal of fungi (Basel), 2023-11, Vol.9 (11), p.1098

2023

Volltextzugriff (PDF)

The catalytic activity and structure of the lipid metabolizing CYP124 cytochrome P450 enzyme from Mycobacterium marinum

Archives of biochemistry and biophysics, 2023-03, Vol.737, p.109554-109554, Article 109554

2023

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The oxidation of cholesterol derivatives by the CYP124 and CYP142 enzymes from Mycobacterium marinum

The Journal of steroid biochemistry and molecular biology, 2023-07, Vol.231, p.106317-106317, Article 106317

2023

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An antimony-phosphomolybdate microassay of ATPase activity through the detection of inorganic phosphate

Analytical biochemistry, 2021-06, Vol.623, p.114170-114170, Article 114170

2021

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Proteoliposomes reconstituted with human aquaporin-1 reveal novel single-ion-channel properties

Biophysical reports, 2023-03, Vol.3 (1), p.100100-100100, Article 100100

2023

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Comparative functional and structural analysis of Pseudomonas aeruginosa d‐alanine–d‐alanine ligase isoforms as prospective antibiotic targets

The FEBS journal, 2023-12, Vol.290 (23), p.5536-5553

2023

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Nucleoside selectivity of Aspergillus fumigatus nucleoside‐diphosphate kinase

The FEBS journal, 2021-04, Vol.288 (7), p.2398-2417

2021

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Engineering potassium activation into biosynthetic thiolase

Biochemical journal, 2021-08, Vol.478 (15), p.3047-3062

2021

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The therapeutic potential of inhibiting PPARγ phosphorylation to treat type 2 diabetes

Review of the Structural and Dynamic Mechanisms of PPARγ Partial Agonism

A comparison of the bacterial CYP51 cytochrome P450 enzymes from Mycobacterium marinum and Mycobacterium tuberculosis

Structural mechanism for signal transduction in RXR nuclear receptor heterodimers

Expressing a moth abcc2 gene in transgenic Drosophila causes susceptibility to Bt Cry1Ac without requiring a cadherin-like protein receptor

DNA binding alters coactivator interaction surfaces of the intact VDR-RXR complex

Structure of the Mycobacterium tuberculosis d-Alanine:d-Alanine Ligase, a Target of the Antituberculosis Drug d-Cycloserine

Loss-of-function mutations in SIM1 contribute to obesity and Prader-Willi-like features

HDX reveals the conformational dynamics of DNA sequence specific VDR co-activator interactions

Coupling of receptor conformation and ligand orientation determine graded activity

Targeting Unconventional Pathways in Pursuit of Novel Antifungals

Biochemical and in silico characterization of glycosyltransferases from red sweet cherry (Prunus avium L.) reveals their broad specificity toward phenolic substrates

Mycobacterium tuberculosis Dethiobiotin Synthetase Facilitates Nucleoside Triphosphate Promiscuity through Alternate Binding Modes

Human variants in the neuronal basic helix-loop-helix/Per-Arnt-Sim (bHLH/PAS) transcription factor complex NPAS4/ARNT2 disrupt function

JAK2 Alterations in Acute Lymphoblastic Leukemia: Molecular Insights for Superior Precision Medicine Strategies

Acquired JAK2 mutations confer resistance to JAK inhibitors in cell models of acute lymphoblastic leukemia

PPARγ in Complex with an Antagonist and Inverse Agonist: a Tumble and Trap Mechanism of the Activation Helix

Towards a High-Affinity Peptidomimetic Targeting Proliferating Cell Nuclear Antigen from Aspergillus fumigatus

The catalytic activity and structure of the lipid metabolizing CYP124 cytochrome P450 enzyme from Mycobacterium marinum

The oxidation of cholesterol derivatives by the CYP124 and CYP142 enzymes from Mycobacterium marinum

An antimony-phosphomolybdate microassay of ATPase activity through the detection of inorganic phosphate

Proteoliposomes reconstituted with human aquaporin-1 reveal novel single-ion-channel properties

Comparative functional and structural analysis of Pseudomonas aeruginosa d‐alanine–d‐alanine ligase isoforms as prospective antibiotic targets

Nucleoside selectivity of Aspergillus fumigatus nucleoside‐diphosphate kinase

Engineering potassium activation into biosynthetic thiolase

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