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Peginterferon Alfa-2a in Patients with Chronic Hepatitis C

The New England journal of medicine, 2000-12, Vol.343 (23), p.1666-1672

2000

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Interleukin-12

Journal of leukocyte biology, 1994-02, Vol.55 (2), p.280-288

BRUNDA, M. J

1994

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Antitumor and antimetastatic activity of interleukin 12 against murine tumors

The Journal of experimental medicine, 1993-10, Vol.178 (4), p.1223-1230

1993

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Recombinant IL-12 administration induces tumor regression in association with IFN-gamma production

The Journal of immunology (1950), 1994-08, Vol.153 (4), p.1697-1706

1994

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Antitumor Efficacy of Adenocarcinoma Cells Engineered to Produce Interleukin 12 (IL-12) or Other Cytokines Compared With Exogenous IL-12

JNCI : Journal of the National Cancer Institute, 1997-07, Vol.89 (14), p.1049-1058

1997

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Efficacy and Safety of Two-Dose Regimens of Peginterferon Alpha-2a Compared with Interferon Alpha-2a in Chronic Hepatitis C: A Multicenter, Randomized Controlled Trial

The American journal of gastroenterology, 2004-07, Vol.99 (7), p.1298-1305

2004

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Administration of Interleukin 12 With Pulse Interleukin 2 and the Rapid and Complete Eradication of Murine Renal Carcinoma

JNCI : Journal of the National Cancer Institute, 1996-01, Vol.88 (1), p.38-43

1996

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Complete Regression of Established Spontaneous Mammary Carcinoma and the Therapeutic Prevention of Genetically Programmed Neoplastic Transition by IL-12/Pulse IL-2: Induction of Local T Cell Infiltration, Fas/Fas Ligand Gene Expression, and Mammary Epithelial Apoptosis

The Journal of immunology (1950), 2001-01, Vol.166 (2), p.1156-1168

2001

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Role of interferon-gamma in mediating the antitumor efficacy of interleukin-12

Journal of immunotherapy (1997), 1995-02, Vol.17 (2), p.71-77

1995

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IL-12 Administration Leads to a Transient Depletion of T Cells, B Cells, and APCs and Concomitant Abrogation of the HLA-A2.1-Restricted CTL Response in Transgenic Mice

The Journal of immunology (1950), 2002-07, Vol.169 (1), p.63-67

2002

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Correction: Immunodominance of cytotoxic T lymphocyte epitopes co‐injected in vivo and modulation by interleukin‐12, Vol 26 (11) 1996, 2709–2716

European journal of immunology, 2005-08, Vol.35 (8), p.2508-2508

2005

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Recruitment of hepatic NK cells by IL-12 is dependent on IFN-gamma and VCAM-1 and is rapidly down-regulated by a mechanism involving T cells and expression of Fas

The Journal of immunology (1950), 1998-12, Vol.161 (11), p.6014-6021

1998

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Interleukin 12 primes macrophages for nitric oxide production in vivo and restores depressed nitric oxide production by macrophages from tumor-bearing mice : Implications for the antitumor activity of interleukin 12 and/or interleukin 2

Cancer research (Chicago, Ill.), 1996-03, Vol.56 (5), p.1131-1136

1996

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Antitumor activity of interleukin 12 in preclinical models

Cancer chemotherapy and pharmacology, 1996-01, Vol.38, p.S16-S21

1996

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Regulation of local host-mediated anti-tumor mechanisms by cytokines: direct and indirect effects on leukocyte recruitment and angiogenesis

The American journal of pathology, 1997-05, Vol.150 (5), p.1869-1880

1997

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Interleukin-12 enhances peripheral hematopoiesis in vivo

Blood, 1995-05, Vol.85 (9), p.2371-2376

1995

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Human Renal Carcinoma Line Transfected With Interleukin-2 and/or Interferon α Gene(s): Implications for Live Cancer Vaccines

JNCI : Journal of the National Cancer Institute, 1993-02, Vol.85 (3), p.207-216

1993

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Interferon immunogenicity: preclinical evaluation of interferon-alpha 2a

Journal of interferon & cytokine research, 1997-07, Vol.17 Suppl 1, p.S23-S27

1997

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Immunodominance of cytotoxic T lymphocyte epitopes co‐injected in vivo and modulation by interleukin‐12

European journal of immunology, 1996-11, Vol.26 (11), p.2709-2716

1996

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Antitumor and antimetastatic activity of interleukin-12

Current topics in microbiology and immunology, 1996, Vol.213 ( Pt 3), p.65

1996

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Interaction of recombinant interferons with recombinant interleukin‐2: Differential effects on natural killer cell activity and interleukin‐2‐activated killer cells

International journal of cancer, 1986-05, Vol.37 (5), p.787-793

1986

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Interleukin-12: Murine Models of a Potent Antitumor Agent

Annals of the New York Academy of Sciences, 1996-10, Vol.795 (1), p.266-274

1996

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Inhibition of murine natural killer cell activity by prostaglandins

The Journal of immunology (1950), 1980-06, Vol.124 (6), p.2682-2687

1980

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In vivo therapeutic effects of interleukin-12 against highly metastatic residual lymphoma

Clinical & experimental metastasis, 1996-05, Vol.14 (3), p.219-229

1996

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Modulation of murine natural killer cell activity in vitro and in vivo by recombinant human interferons

Cancer research (Chicago, Ill.), 1984-02, Vol.44 (2), p.597-601

1984

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Peginterferon Alfa-2a in Patients with Chronic Hepatitis C

Interleukin-12

Antitumor and antimetastatic activity of interleukin 12 against murine tumors

Recombinant IL-12 administration induces tumor regression in association with IFN-gamma production

Antitumor Efficacy of Adenocarcinoma Cells Engineered to Produce Interleukin 12 (IL-12) or Other Cytokines Compared With Exogenous IL-12

Efficacy and Safety of Two-Dose Regimens of Peginterferon Alpha-2a Compared with Interferon Alpha-2a in Chronic Hepatitis C: A Multicenter, Randomized Controlled Trial

Administration of Interleukin 12 With Pulse Interleukin 2 and the Rapid and Complete Eradication of Murine Renal Carcinoma

Complete Regression of Established Spontaneous Mammary Carcinoma and the Therapeutic Prevention of Genetically Programmed Neoplastic Transition by IL-12/Pulse IL-2: Induction of Local T Cell Infiltration, Fas/Fas Ligand Gene Expression, and Mammary Epithelial Apoptosis

Role of interferon-gamma in mediating the antitumor efficacy of interleukin-12

IL-12 Administration Leads to a Transient Depletion of T Cells, B Cells, and APCs and Concomitant Abrogation of the HLA-A2.1-Restricted CTL Response in Transgenic Mice

Correction: Immunodominance of cytotoxic T lymphocyte epitopes co‐injected in vivo and modulation by interleukin‐12, Vol 26 (11) 1996, 2709–2716

Recruitment of hepatic NK cells by IL-12 is dependent on IFN-gamma and VCAM-1 and is rapidly down-regulated by a mechanism involving T cells and expression of Fas

Interleukin 12 primes macrophages for nitric oxide production in vivo and restores depressed nitric oxide production by macrophages from tumor-bearing mice : Implications for the antitumor activity of interleukin 12 and/or interleukin 2

Antitumor activity of interleukin 12 in preclinical models

Regulation of local host-mediated anti-tumor mechanisms by cytokines: direct and indirect effects on leukocyte recruitment and angiogenesis

Interleukin-12 enhances peripheral hematopoiesis in vivo

Human Renal Carcinoma Line Transfected With Interleukin-2 and/or Interferon α Gene(s): Implications for Live Cancer Vaccines

Interferon immunogenicity: preclinical evaluation of interferon-alpha 2a

Immunodominance of cytotoxic T lymphocyte epitopes co‐injected in vivo and modulation by interleukin‐12

Antitumor and antimetastatic activity of interleukin-12

Interaction of recombinant interferons with recombinant interleukin‐2: Differential effects on natural killer cell activity and interleukin‐2‐activated killer cells

Interleukin-12: Murine Models of a Potent Antitumor Agent

Inhibition of murine natural killer cell activity by prostaglandins

In vivo therapeutic effects of interleukin-12 against highly metastatic residual lymphoma

Modulation of murine natural killer cell activity in vitro and in vivo by recombinant human interferons

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