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DNA repair in mammalian mitochondria: Much more than we thought

Environmental and molecular mutagenesis, 2010-06, Vol.51 (5), p.417-426

2010

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Knockout and Inhibition of Ape1: Roles of Ape1 in Base Excision DNA Repair and Modulation of Gene Expression

Antioxidants, 2022-09, Vol.11 (9), p.1817

2022

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Human AP-endonuclease (Ape1) activity on telomeric G4 structures is modulated by acetylatable lysine residues in the N-terminal sequence

DNA repair, 2019-01, Vol.73, p.129-143

2019

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Enzyme mechanism-based, oxidative DNA–protein cross-links formed with DNA polymeraseβin vivo

Proceedings of the National Academy of Sciences - PNAS, 2015-07, Vol.112 (28), p.8602-8607

2015

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Essential role for mammalian apurinic/apyrimidinic (AP) endonuclease Ape1/Ref-1 in telomere maintenance

Proceedings of the National Academy of Sciences - PNAS, 2013-10, Vol.110 (44), p.17844-17849

2013

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Maintenance of Flap Endonucleases for Long-Patch Base Excision DNA Repair in Mouse Muscle and Neuronal Cells Differentiated In Vitro

International journal of molecular sciences, 2023-08, Vol.24 (16), p.12715

2023

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Human DNA2 Is a Mitochondrial Nuclease/Helicase for Efficient Processing of DNA Replication and Repair Intermediates

Molecular cell, 2008-11, Vol.32 (3), p.325-336

2008

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Direct Nitric Oxide Signal Transduction via Nitrosylation of Iron-Sulfur Centers in the SoxR Transcription Activator

Proceedings of the National Academy of Sciences - PNAS, 2000-05, Vol.97 (10), p.5146-5150

2000

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Roles of base excision repair subpathways in correcting oxidized abasic sites in DNA

The FEBS journal, 2006-04, Vol.273 (8), p.1620-1629

2006

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Removal of Oxidative DNA Damage via FEN1-Dependent Long-Patch Base Excision Repair in Human Cell Mitochondria

Molecular and Cellular Biology, 2008-08, Vol.28 (16), p.4975-4987

2008

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Redox-operated genetic switches: the SoxR and OxyR transcription factors

Trends in Biotechnology, 2001-03, Vol.19 (3), p.109-114

2001

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How are base excision DNA repair pathways deployed in vivo ?

F1000 research, 2017, Vol.6, p.279-279

2017

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Redox signaling and gene control in the Escherichia coli soxRS oxidative stress regulon — a review

Gene, 1996-11, Vol.179 (1), p.53-57

Demple, Bruce

1996

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DNA-mediated redox signaling for transcriptional activation of SoxR

Proceedings of the National Academy of Sciences - PNAS, 2009-08, Vol.106 (32), p.13164-13168

2009

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Repair of Oxidative Damage to DNA: Enzymology and Biology

Annual review of biochemistry, 1994-01, Vol.63 (1), p.915-948

1994

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Deployment of DNA polymerases beta and lambda in single-nucleotide and multinucleotide pathways of mammalian base excision DNA repair

DNA repair, 2019-04, Vol.76, p.11-19

2019

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ATF4-Dependent Oxidative Induction of the DNA Repair Enzyme Ape1 Counteracts Arsenite Cytotoxicity and Suppresses Arsenite-Mediated Mutagenesis

Molecular and Cellular Biology, 2007-12, Vol.27 (24), p.8834-8847

2007

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Constitutive soxR Mutations Contribute to Multiple-Antibiotic Resistance in Clinical Escherichia coli Isolates

Antimicrobial Agents and Chemotherapy, 2005-07, Vol.49 (7), p.2746-2752

2005

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Assessing Toxicity and Nuclear and Mitochondrial DNA Damage Caused by Exposure of Mammalian Cells to Lunar Regolith Simulants

Geohealth, 2018-04, Vol.2 (4), p.139-148

2018

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Terminally differentiated muscle cells are defective in base excision DNA repair and hypersensitive to oxygen injury

Proceedings of the National Academy of Sciences - PNAS, 2007-10, Vol.104 (43), p.17010-17015

2007

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Analysis of Nitric Oxide-Stabilized mRNAs in Human Fibroblasts Reveals HuR-Dependent Heme Oxygenase 1 Upregulation

Molecular and Cellular Biology, 2009-05, Vol.29 (10), p.2622-2635

2009

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Distinct Roles of Ape1 Protein in the Repair of DNA Damage Induced by Ionizing Radiation or Bleomycin

The Journal of biological chemistry, 2011-02, Vol.286 (7), p.4968-4977

2011

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Fractionated Radiation Exposure of Rat Spinal Cords Leads to Latent Neuro-Inflammation in Brain, Cognitive Deficits, and Alterations in Apurinic Endonuclease 1

PloS one, 2015-07, Vol.10 (7), p.e0133016-e0133016

2015

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Dynamics and diversions in base excision DNA repair of oxidized abasic lesions

Oncogene, 2002-12, Vol.21 (58), p.8926-8934

2002

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DNA repair in mammalian mitochondria: Much more than we thought

Knockout and Inhibition of Ape1: Roles of Ape1 in Base Excision DNA Repair and Modulation of Gene Expression

Human AP-endonuclease (Ape1) activity on telomeric G4 structures is modulated by acetylatable lysine residues in the N-terminal sequence

Enzyme mechanism-based, oxidative DNA–protein cross-links formed with DNA polymeraseβin vivo

Essential role for mammalian apurinic/apyrimidinic (AP) endonuclease Ape1/Ref-1 in telomere maintenance

Maintenance of Flap Endonucleases for Long-Patch Base Excision DNA Repair in Mouse Muscle and Neuronal Cells Differentiated In Vitro

Human DNA2 Is a Mitochondrial Nuclease/Helicase for Efficient Processing of DNA Replication and Repair Intermediates

Genomic Instability and Aging-like Phenotype in the Absence of Mammalian SIRT6

Direct Nitric Oxide Signal Transduction via Nitrosylation of Iron-Sulfur Centers in the SoxR Transcription Activator

Roles of base excision repair subpathways in correcting oxidized abasic sites in DNA

Removal of Oxidative DNA Damage via FEN1-Dependent Long-Patch Base Excision Repair in Human Cell Mitochondria

Redox-operated genetic switches: the SoxR and OxyR transcription factors

How are base excision DNA repair pathways deployed in vivo ?

Redox signaling and gene control in the Escherichia coli soxRS oxidative stress regulon — a review

DNA-mediated redox signaling for transcriptional activation of SoxR

Repair of Oxidative Damage to DNA: Enzymology and Biology

Deployment of DNA polymerases beta and lambda in single-nucleotide and multinucleotide pathways of mammalian base excision DNA repair

ATF4-Dependent Oxidative Induction of the DNA Repair Enzyme Ape1 Counteracts Arsenite Cytotoxicity and Suppresses Arsenite-Mediated Mutagenesis

Constitutive soxR Mutations Contribute to Multiple-Antibiotic Resistance in Clinical Escherichia coli Isolates

Assessing Toxicity and Nuclear and Mitochondrial DNA Damage Caused by Exposure of Mammalian Cells to Lunar Regolith Simulants

Terminally differentiated muscle cells are defective in base excision DNA repair and hypersensitive to oxygen injury

Analysis of Nitric Oxide-Stabilized mRNAs in Human Fibroblasts Reveals HuR-Dependent Heme Oxygenase 1 Upregulation

Distinct Roles of Ape1 Protein in the Repair of DNA Damage Induced by Ionizing Radiation or Bleomycin

Fractionated Radiation Exposure of Rat Spinal Cords Leads to Latent Neuro-Inflammation in Brain, Cognitive Deficits, and Alterations in Apurinic Endonuclease 1

Dynamics and diversions in base excision DNA repair of oxidized abasic lesions

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