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AMPK CA(R)Sts a new light on amino acid sensing

The EMBO journal, 2021-11, Vol.40 (21), p.e109575-n/a

Brown, Kristin K

2021

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The phosphoinositide 3-kinase pathway and therapy resistance in cancer

F1000 prime reports, 2015-02, Vol.7, p.13-13

2015

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Yap reprograms glutamine metabolism to increase nucleotide biosynthesis and enable liver growth

Nature cell biology, 2016-08, Vol.18 (8), p.886-896

2016

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Autolytic Proteolysis within the Function to Find Domain (FIIND) Is Required for NLRP1 Inflammasome Activity

The Journal of biological chemistry, 2012-07, Vol.287 (30), p.25030-25037

2012

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Biological targets of isothiocyanates

Biochimica et biophysica acta, 2011-09, Vol.1810 (9), p.888-894

2011

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Type IIA topoisomerase inhibition by a new class of antibacterial agents

Nature (London), 2010-08, Vol.466 (7309), p.935-940

2010

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YAP regulates an SGK1/mTORC1/SREBP-dependent lipogenic program to support proliferation and tissue growth

Developmental cell, 2022-03, Vol.57 (6), p.719-731.e8

2022

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MERIT40 Is an Akt Substrate that Promotes Resolution of DNA Damage Induced by Chemotherapy

Cell reports (Cambridge), 2015-06, Vol.11 (9), p.1358-1366

2015

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PKD Controls αvβ3 Integrin Recycling and Tumor Cell Invasive Migration through Its Substrate Rabaptin-5

Developmental cell, 2012-09, Vol.23 (3), p.560-572

2012

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Glutamine addiction promotes glucose oxidation in triple-negative breast cancer

Oncogene, 2022-08, Vol.41 (34), p.4066-4078

2022

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Yap regulates glucose utilization and sustains nucleotide synthesis to enable organ growth

The EMBO journal, 2018-11, Vol.37 (22), p.n/a

2018

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Tumor immune evasion arises through loss of TNF sensitivity

Science immunology, 2018-05, Vol.3 (23)

2018

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Efficient Biocatalytic Reductive Aminations by Extending the Imine Reductase Toolbox

ChemCatChem, 2017-12, Vol.9 (24), p.4475-4479

2017

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Serine Biosynthesis Is a Metabolic Vulnerability in FLT3-ITD-Driven Acute Myeloid Leukemia

Cancer discovery, 2021-06, Vol.11 (6), p.1582-1599

2021

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The KEAP1-NRF2 pathway regulates TFEB/TFE3-dependent lysosomal biogenesis

Proceedings of the National Academy of Sciences - PNAS, 2023-05, Vol.120 (22), p.e2217425120-e2217425120

2023

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Metals in the stomach contents and brain, gonad, kidney, and liver tissues of subsistence-harvested northern sea otters (Enhydra lutris kenyoni) from Icy Strait, Alaska

Marine pollution bulletin, 2021-05, Vol.166, p.112183, Article 112183

2021

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Characterization of the Src-regulated kinome identifies SGK1 as a key mediator of Src-induced transformation

Nature communications, 2019-01, Vol.10 (1), p.296-16, Article 296

2019

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Approaches to target tractability assessment - a practical perspective

MedChemComm, 2018-04, Vol.9 (4), p.606-613

2018

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Detection of pleiotropy through a Phenome-wide association study (PheWAS) of epidemiologic data as part of the Environmental Architecture for Genes Linked to Environment (EAGLE) study

PLoS genetics, 2014-12, Vol.10 (12), p.e1004678

2014

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SLAM-ITseq identifies that Nrf2 induces liver regeneration through the pentose phosphate pathway

Developmental cell, 2024-04, Vol.59 (7), p.898-910.e6

2024

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Biocatalytic Synthesis of Chiral N‐Functionalized Amino Acids

Angewandte Chemie International Edition, 2018-10, Vol.57 (42), p.13821-13824

International ed. in English, 2018

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A human fatty acid synthase inhibitor binds β-ketoacyl reductase in the keto-substrate site

Nature chemical biology, 2014-09, Vol.10 (9), p.774-779

2014

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Selenoprotein H is an essential regulator of redox homeostasis that cooperates with p53 in development and tumorigenesis

Proceedings of the National Academy of Sciences - PNAS, 2016-09, Vol.113 (38), p.E5562-E5571

2016

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A Comprehensive Approach to Assuring Quality of Laboratory Testing in HIV Surveys: Lessons Learned From the Population-Based HIV Impact Assessment Project

Journal of acquired immune deficiency syndromes (1999), 2021-08, Vol.87 (Suppl 1), p.S17-S27

2021

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AMPK CA(R)Sts a new light on amino acid sensing

The phosphoinositide 3-kinase pathway and therapy resistance in cancer

Yap reprograms glutamine metabolism to increase nucleotide biosynthesis and enable liver growth

Autolytic Proteolysis within the Function to Find Domain (FIIND) Is Required for NLRP1 Inflammasome Activity

Biological targets of isothiocyanates

Type IIA topoisomerase inhibition by a new class of antibacterial agents

YAP regulates an SGK1/mTORC1/SREBP-dependent lipogenic program to support proliferation and tissue growth

MERIT40 Is an Akt Substrate that Promotes Resolution of DNA Damage Induced by Chemotherapy

Pharmacologic Reduction of Mitochondrial Iron Triggers a Noncanonical BAX/BAK-Dependent Cell Death

PKD Controls αvβ3 Integrin Recycling and Tumor Cell Invasive Migration through Its Substrate Rabaptin-5

Glutamine addiction promotes glucose oxidation in triple-negative breast cancer

Yap regulates glucose utilization and sustains nucleotide synthesis to enable organ growth

Tumor immune evasion arises through loss of TNF sensitivity

Efficient Biocatalytic Reductive Aminations by Extending the Imine Reductase Toolbox

Serine Biosynthesis Is a Metabolic Vulnerability in FLT3-ITD-Driven Acute Myeloid Leukemia

The KEAP1-NRF2 pathway regulates TFEB/TFE3-dependent lysosomal biogenesis

Metals in the stomach contents and brain, gonad, kidney, and liver tissues of subsistence-harvested northern sea otters (Enhydra lutris kenyoni) from Icy Strait, Alaska

Characterization of the Src-regulated kinome identifies SGK1 as a key mediator of Src-induced transformation

Approaches to target tractability assessment - a practical perspective

Detection of pleiotropy through a Phenome-wide association study (PheWAS) of epidemiologic data as part of the Environmental Architecture for Genes Linked to Environment (EAGLE) study

SLAM-ITseq identifies that Nrf2 induces liver regeneration through the pentose phosphate pathway

Biocatalytic Synthesis of Chiral N‐Functionalized Amino Acids

A human fatty acid synthase inhibitor binds β-ketoacyl reductase in the keto-substrate site

Selenoprotein H is an essential regulator of redox homeostasis that cooperates with p53 in development and tumorigenesis

A Comprehensive Approach to Assuring Quality of Laboratory Testing in HIV Surveys: Lessons Learned From the Population-Based HIV Impact Assessment Project

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