UB Paderborn / Katalog / Suche / in CDI

1 – 25 von 464

Sortiert nach

Analysis of Past and Present Synthetic Methodologies on Medicinal Chemistry: Where Have All the New Reactions Gone?

Journal of medicinal chemistry, 2016-05, Vol.59 (10), p.4443-4458

2016

Link zum Volltext

Verfügbarkeit prüfen

Expanding the medicinal chemistry synthetic toolbox

Nature reviews. Drug discovery, 2018-10, Vol.17 (10), p.709-727

2018

Link zum Volltext

Verfügbarkeit prüfen

ESKAPEing the labyrinth of antibacterial discovery

Nature reviews. Drug discovery, 2015-08, Vol.14 (8), p.529-542

2015

Link zum Volltext

Verfügbarkeit prüfen

Clinical development times for innovative drugs

Nature reviews. Drug discovery, 2022-11, Vol.21 (11), p.793-794

2022

Link zum Volltext

Verfügbarkeit prüfen

Trends and Exceptions of Physical Properties on Antibacterial Activity for Gram-Positive and Gram-Negative Pathogens

Journal of medicinal chemistry, 2014-12, Vol.57 (23), p.10144-10161

2014

Link zum Volltext

Verfügbarkeit prüfen

Impact of a five-dimensional framework on R&D productivity at AstraZeneca

Nature reviews. Drug discovery, 2018-03, Vol.17 (3), p.167-181

2018

Link zum Volltext

Verfügbarkeit prüfen

Prolonged tau clearance and stress vulnerability rescue by pharmacological activation of autophagy in tauopathy neurons

Nature communications, 2020-06, Vol.11 (1), p.3258-3258, Article 3258

2020

Link zum Volltext

Verfügbarkeit prüfen

New natural products as new leads for antibacterial drug discovery

Bioorganic & medicinal chemistry letters, 2014-01, Vol.24 (2), p.413-418

2014

Link zum Volltext

Verfügbarkeit prüfen

An Analysis of Successful Hit-to-Clinical Candidate Pairs

Journal of medicinal chemistry, 2023-06, Vol.66 (11), p.7101-7139

Brown, Dean G.

2023

Link zum Volltext

Verfügbarkeit prüfen

A Decade of FDA-Approved Drugs (2010–2019): Trends and Future Directions

Journal of medicinal chemistry, 2021-03, Vol.64 (5), p.2312-2338

2021

Link zum Volltext

Verfügbarkeit prüfen

Adapting to the Changing Landscape of Biotech-Driven Drug Discovery

Journal of medicinal chemistry, 2023-12, Vol.66 (23), p.15580-15585

Brown, Dean G.

2023

Link zum Volltext

Verfügbarkeit prüfen

A Drug Discovery Perspective on FDA Expedited Development and Incentive Programs

Journal of medicinal chemistry, 2024-02, Vol.67 (3), p.1690-1700

Brown, Dean G.

2024

Link zum Volltext

Verfügbarkeit prüfen

Novel Antibacterial Targets and Compounds Revealed by a High-Throughput Cell Wall Reporter Assay

Journal of bacteriology, 2015-05, Vol.197 (10), p.1726-1734

2015

Link zum Volltext

Verfügbarkeit prüfen

Correction to “An Analysis of Successful Hit-to-Clinical Candidate Pairs”

Journal of medicinal chemistry, 2023-07, Vol.66 (13), p.9225-9226

Brown, Dean G.

2023

Link zum Volltext

Verfügbarkeit prüfen

Where Do Recent Small Molecule Clinical Development Candidates Come From?

Journal of medicinal chemistry, 2018-11, Vol.61 (21), p.9442-9468

2018

Link zum Volltext

Verfügbarkeit prüfen

Tool inhibitors and assays to interrogate the biology of the TRAF2 and NCK interacting kinase

Bioorganic & medicinal chemistry letters, 2019-08, Vol.29 (15), p.1962-1967

2019

Link zum Volltext

Verfügbarkeit prüfen

Drug discovery strategies to outer membrane targets in Gram-negative pathogens

Bioorganic & medicinal chemistry, 2016-12, Vol.24 (24), p.6320-6331

Brown, Dean G.

2016

Link zum Volltext

Verfügbarkeit prüfen

Opportunities and Challenges in Phenotypic Screening for Neurodegenerative Disease Research

Journal of medicinal chemistry, 2020-03, Vol.63 (5), p.1823-1840

2020

Link zum Volltext

Verfügbarkeit prüfen

Axl receptor tyrosine kinase is a regulator of apolipoprotein E

Molecular brain, 2020-05, Vol.13 (1), p.66-66, Article 66

2020

Link zum Volltext

Verfügbarkeit prüfen

Analysis of orphan designation status for FDA approved drugs, and case studies in oncology, neuroscience and metabolic diseases

Bioorganic & medicinal chemistry, 2023-02, Vol.80, p.117170-117170, Article 117170

2023

Link zum Volltext

Verfügbarkeit prüfen

In vitro metabolism studies of nomifensine monooxygenation pathways: metabolite identification, reaction phenotyping, and bioactivation mechanism

Drug metabolism and disposition, 2010-10, Vol.38 (10), p.1767

2010

Link zum Volltext

Verfügbarkeit prüfen

The clinical trial landscape in amyotrophic lateral sclerosis—Past, present, and future

Medicinal research reviews, 2020-07, Vol.40 (4), p.1352-1384

2020

Link zum Volltext

Verfügbarkeit prüfen

Some Observations and Guidance on Perspectives in the Journal of Medicinal Chemistry

Journal of medicinal chemistry, 2023-02, Vol.66 (4), p.2209-2210

2023

Link zum Volltext

Verfügbarkeit prüfen

Protease-activated receptor-2 ligands reveal orthosteric and allosteric mechanisms of receptor inhibition

Communications biology, 2020-12, Vol.3 (1), p.782-782, Article 782

2020

Link zum Volltext

Verfügbarkeit prüfen

A survey of the clinical pipeline in neuroscience

Bioorganic & medicinal chemistry letters, 2022-01, Vol.56, p.128482-128482, Article 128482

2022

Link zum Volltext

Verfügbarkeit prüfen

1 – 25 von 464

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(422)
Mit Volltextzugriff
(400)

Publikationsform

2 weitere anzeigen...

Weniger anzeigen...

Sprache

1 weiteren anzeigen...

Weniger anzeigen...

Erscheinungsjahr

n.n

Thema

15 weitere anzeigen...

Weniger anzeigen...

Neu hinzugefügt

... seit 90 Tagen
(1)

Menü

Weitere Dienste

Einstellungen

Analysis of Past and Present Synthetic Methodologies on Medicinal Chemistry: Where Have All the New Reactions Gone?

Expanding the medicinal chemistry synthetic toolbox

ESKAPEing the labyrinth of antibacterial discovery

Clinical development times for innovative drugs

Trends and Exceptions of Physical Properties on Antibacterial Activity for Gram-Positive and Gram-Negative Pathogens

Impact of a five-dimensional framework on R&D productivity at AstraZeneca

Prolonged tau clearance and stress vulnerability rescue by pharmacological activation of autophagy in tauopathy neurons

New natural products as new leads for antibacterial drug discovery

An Analysis of Successful Hit-to-Clinical Candidate Pairs

A Decade of FDA-Approved Drugs (2010–2019): Trends and Future Directions

Adapting to the Changing Landscape of Biotech-Driven Drug Discovery

A Drug Discovery Perspective on FDA Expedited Development and Incentive Programs

Novel Antibacterial Targets and Compounds Revealed by a High-Throughput Cell Wall Reporter Assay

Correction to “An Analysis of Successful Hit-to-Clinical Candidate Pairs”

Where Do Recent Small Molecule Clinical Development Candidates Come From?

Tool inhibitors and assays to interrogate the biology of the TRAF2 and NCK interacting kinase

Drug discovery strategies to outer membrane targets in Gram-negative pathogens

Opportunities and Challenges in Phenotypic Screening for Neurodegenerative Disease Research

Axl receptor tyrosine kinase is a regulator of apolipoprotein E

Analysis of orphan designation status for FDA approved drugs, and case studies in oncology, neuroscience and metabolic diseases

In vitro metabolism studies of nomifensine monooxygenation pathways: metabolite identification, reaction phenotyping, and bioactivation mechanism

The clinical trial landscape in amyotrophic lateral sclerosis—Past, present, and future

Some Observations and Guidance on Perspectives in the Journal of Medicinal Chemistry

Protease-activated receptor-2 ligands reveal orthosteric and allosteric mechanisms of receptor inhibition

A survey of the clinical pipeline in neuroscience

Suchergebnisse filtern