UB Paderborn / Katalog / Suche / in CDI

1 – 25 von 228

Sortiert nach

Key Role for the 12-Hydroxy Group in the Negative Ion Fragmentation of Unconjugated C24 Bile Acids

Analytical chemistry (Washington), 2016-07, Vol.88 (14), p.7041-7048

2016

Volltextzugriff (PDF)

Effect of Liver Disease on Hepatic Transporter Expression and Function

Journal of pharmaceutical sciences, 2017-09, Vol.106 (9), p.2282-2294

2017

Volltextzugriff (PDF)

Disease‐Associated Changes in Drug Transporters May Impact the Pharmacokinetics and/or Toxicity of Drugs: A White Paper From the International Transporter Consortium

Clinical pharmacology and therapeutics, 2018-11, Vol.104 (5), p.900-915

2018

Volltextzugriff (PDF)

Can Bile Salt Export Pump Inhibition Testing in Drug Discovery and Development Reduce Liver Injury Risk? An International Transporter Consortium Perspective

Clinical pharmacology and therapeutics, 2018-11, Vol.104 (5), p.916-932

2018

Volltextzugriff (PDF)

Advancing Predictions of Tissue and Intracellular Drug Concentrations Using In Vitro, Imaging and Physiologically Based Pharmacokinetic Modeling Approaches

Clinical pharmacology and therapeutics, 2018-11, Vol.104 (5), p.865-889

2018

Volltextzugriff (PDF)

In vitro to in vivo extrapolation for high throughput prioritization and decision making

Toxicology in vitro, 2018-03, Vol.47, p.213-227

2018

Volltextzugriff (PDF)

An updated review on drug-induced cholestasis: Mechanisms and investigation of physicochemical properties and pharmacokinetic parameters

Journal of pharmaceutical sciences, 2013-09, Vol.102 (9), p.3037-3057

2013

Volltextzugriff (PDF)

Analysis of human C24 bile acids metabolome in serum and urine based on enzyme digestion of conjugated bile acids and LC-MS determination of unconjugated bile acids

Analytical and bioanalytical chemistry, 2018-08, Vol.410 (21), p.5287-5300

2018

Volltextzugriff (PDF)

The role of hepatic transporters in drug disposition and elimination

Drug metabolism and pharmacokinetics, 2018-01, Vol.33 (1), p.S2-S2

Brouwer, Kim L.R.

2018

Volltextzugriff (PDF)

Role of hepatic efflux transporters in regulating systemic and hepatocyte exposure to xenobiotics

Annual review of pharmacology and toxicology, 2014-01, Vol.54 (1), p.509-535

2014

Volltextzugriff (PDF)

Application of a Mechanistic Model to Evaluate Putative Mechanisms of Tolvaptan Drug-Induced Liver Injury and Identify Patient Susceptibility Factors

Toxicological sciences, 2017-01, Vol.155 (1), p.61-74

2017

Volltextzugriff (PDF)

Altered Expression and Function of Hepatic Transporters in a Rodent Model of Polycystic Kidney Disease

Drug metabolism and disposition, 2019-08, Vol.47 (8), p.899-906

2019

Volltextzugriff (PDF)

Sandwich-Cultured Hepatocytes as a Tool to Study Drug Disposition and Drug-Induced Liver Injury

Journal of pharmaceutical sciences, 2016-02, Vol.105 (2), p.443-459

2016

Volltextzugriff (PDF)

Protein expression and function of organic anion transporters in short-term and long-term cultures of Huh7 human hepatoma cells

European journal of pharmaceutical sciences, 2019-03, Vol.130, p.186-195

2019

Volltextzugriff (PDF)

Influence of Drug Transport Proteins on the Pharmacokinetics and Drug Interactions of Hiv Protease Inhibitors

Journal of pharmaceutical sciences, 2011-09, Vol.100 (9), p.3636-3654

2011

Volltextzugriff (PDF)

Precision Dosing: Public Health Need, Proposed Framework, and Anticipated Impact

Clinical and translational science, 2017-11, Vol.10 (6), p.443-454

2017

Volltextzugriff (PDF)

Medication use and medical comorbidity in patients with chronic hepatitis C from a US commercial claims database: high utilization of drugs with interaction potential

European journal of gastroenterology & hepatology, 2014-10, Vol.26 (10), p.1073-1082

2014

Volltextzugriff (PDF)

Exploring BSEP inhibition-mediated toxicity with a mechanistic model of drug-induced liver injury

Frontiers in pharmacology, 2014, Vol.5, p.240-240

2014

Volltextzugriff (PDF)

Integration of hepatic drug transporters and phase II metabolizing enzymes: Mechanisms of hepatic excretion of sulfate, glucuronide, and glutathione metabolites

European journal of pharmaceutical sciences, 2006-04, Vol.27 (5), p.447-486

2006

Volltextzugriff (PDF)

Physiologically Based Pharmacokinetic Approach to Determine Dosing on Extracorporeal Life Support: Fluconazole in Children on ECMO

CPT: pharmacometrics and systems pharmacology, 2018-10, Vol.7 (10), p.629-637

2018

Volltextzugriff (PDF)

Probe Cocktail to Assess Transporter Function in Sandwich-Cultured Human Hepatocytes

Journal of pharmacy & pharmaceutical sciences, 2019, Vol.22 (1), p.567

2019

Volltextzugriff (PDF)

Characterization of the Cytochrome P450 epoxyeicosanoid pathway in non-alcoholic steatohepatitis

Prostaglandins & other lipid mediators, 2016-09, Vol.125, p.19-29

2016

Volltextzugriff (PDF)

Polycystic kidney disease alters the hepatobiliary disposition of tolvaptan and metabolites

Drug metabolism and pharmacokinetics, 2018-01, Vol.33 (1), p.S40-S41

2018

Volltextzugriff (PDF)

Correlation of biliary excretion in sandwich-cultured rat hepatocytes and in vivo in rats

Drug metabolism and disposition, 1999-06, Vol.27 (6), p.637

1999

Volltextzugriff (PDF)

Effect of culture conditions on the expression and function of Bsep, Mrp2, and Mdr1a/b in sandwich-cultured rat hepatocytes

Biochemical pharmacology, 2006-05, Vol.71 (10), p.1520-1529

2006

Volltextzugriff (PDF)

1 – 25 von 228

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(220)
Mit Volltextzugriff
(163)

Publikationsform

Artikel
(224)
Buchkapitel
(4)

Sprache

Englisch
(228)
Japanisch
(73)

Erscheinungsjahr

n.n

Thema

15 weitere anzeigen...

Weniger anzeigen...

Neu hinzugefügt

... seit 30 Tagen
(1)

Menü

Weitere Dienste

Einstellungen

Key Role for the 12-Hydroxy Group in the Negative Ion Fragmentation of Unconjugated C24 Bile Acids

Effect of Liver Disease on Hepatic Transporter Expression and Function

Disease‐Associated Changes in Drug Transporters May Impact the Pharmacokinetics and/or Toxicity of Drugs: A White Paper From the International Transporter Consortium

Can Bile Salt Export Pump Inhibition Testing in Drug Discovery and Development Reduce Liver Injury Risk? An International Transporter Consortium Perspective

Advancing Predictions of Tissue and Intracellular Drug Concentrations Using In Vitro, Imaging and Physiologically Based Pharmacokinetic Modeling Approaches

In vitro to in vivo extrapolation for high throughput prioritization and decision making

An updated review on drug-induced cholestasis: Mechanisms and investigation of physicochemical properties and pharmacokinetic parameters

Analysis of human C24 bile acids metabolome in serum and urine based on enzyme digestion of conjugated bile acids and LC-MS determination of unconjugated bile acids

The role of hepatic transporters in drug disposition and elimination

Role of hepatic efflux transporters in regulating systemic and hepatocyte exposure to xenobiotics

Application of a Mechanistic Model to Evaluate Putative Mechanisms of Tolvaptan Drug-Induced Liver Injury and Identify Patient Susceptibility Factors

Altered Expression and Function of Hepatic Transporters in a Rodent Model of Polycystic Kidney Disease

Sandwich-Cultured Hepatocytes as a Tool to Study Drug Disposition and Drug-Induced Liver Injury

Protein expression and function of organic anion transporters in short-term and long-term cultures of Huh7 human hepatoma cells

Influence of Drug Transport Proteins on the Pharmacokinetics and Drug Interactions of Hiv Protease Inhibitors

Precision Dosing: Public Health Need, Proposed Framework, and Anticipated Impact

Medication use and medical comorbidity in patients with chronic hepatitis C from a US commercial claims database: high utilization of drugs with interaction potential

Exploring BSEP inhibition-mediated toxicity with a mechanistic model of drug-induced liver injury

Integration of hepatic drug transporters and phase II metabolizing enzymes: Mechanisms of hepatic excretion of sulfate, glucuronide, and glutathione metabolites

Physiologically Based Pharmacokinetic Approach to Determine Dosing on Extracorporeal Life Support: Fluconazole in Children on ECMO

Probe Cocktail to Assess Transporter Function in Sandwich-Cultured Human Hepatocytes

Characterization of the Cytochrome P450 epoxyeicosanoid pathway in non-alcoholic steatohepatitis

Polycystic kidney disease alters the hepatobiliary disposition of tolvaptan and metabolites

Correlation of biliary excretion in sandwich-cultured rat hepatocytes and in vivo in rats

Effect of culture conditions on the expression and function of Bsep, Mrp2, and Mdr1a/b in sandwich-cultured rat hepatocytes

Suchergebnisse filtern