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Plant-derived human butyrylcholinesterase, but not an organophosphorous-compound hydrolyzing variant thereof, protects rodents against nerve agents

Proceedings of the National Academy of Sciences - PNAS, 2010-11, Vol.107 (47), p.20251-20256

2010

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Comparison of human and guinea pig acetylcholinesterase sequences and rates of oxime-assisted reactivation

Chemico-biological interactions, 2010-09, Vol.187 (1), p.229-233

2010

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A Single Amino Acid Substitution, Gly117His, Confers Phosphotriesterase (Organophosphorus Acid Anhydride Hydrolase) Activity on Human Butyrylcholinesterase

Biochemistry (Easton), 1997-01, Vol.36 (4), p.786-795

1997

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A collaborative endeavor to design cholinesterase-based catalytic scavengers against toxic organophosphorus esters

Chemico-biological interactions, 2008-09, Vol.175 (1), p.273-280

2008

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Design and expression of organophosphorus acid anhydride hydrolase activity in human butyrylcholinesterase

Biochemistry (Easton), 1995-12, Vol.34 (49), p.15925-15933

1995

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Response of normal human keratinocytes to sulfur mustard: cytokine release

Journal of applied toxicology, 2000-12, Vol.20 (S1), p.S63-S72

2000

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The effect of the human serum paraoxonase polymorphism is reversed with diazoxon, soman and sarin

Nature genetics, 1996-11, Vol.14 (3), p.334-336

1996

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Evidence for nonacetylcholinesterase targets of organophosphorus nerve agent: supersensitivity of acetylcholinesterase knockout mouse to VX lethality

The Journal of pharmacology and experimental therapeutics, 2001-11, Vol.299 (2), p.528

2001

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Organophosphorus Acid Anhydride Hydrolase Activity in Human Butyrylcholinesterase: Synergy Results in a Somanase

Biochemistry (Easton), 1998-01, Vol.37 (1), p.237-247

1998

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BIOCHEMICAL ALTERATIONS IN RAT LUNG LAVAGE FLUID FOLLOWING ACUTE SULFUR MUSTARD INHALATION: II. INCREASES IN PROTEOLYTIC ACTIVITY

Inhalation toxicology, 1997, Vol.9 (1), p.53-61

1997

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A review of multi-threat medical countermeasures against chemical warfare and terrorism

Military medicine, 2004-11, Vol.169 (11), p.850-855

2004

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The Role of Interleukin-6 (IL-6) in Human Sulfur Mustard (HD) Toxicology

International journal of toxicology, 2001-09, Vol.20 (5), p.281-296

2001

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Neutralization effects of interleukin-6 (IL-6) antibodies on sulfur mustard (HD)-induced IL-6 secretion on human epidermal keratinocytes

Environmental toxicology and pharmacology, 2004-06, Vol.17 (2), p.87-94

2004

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Exposure of human epidermal keratinocyte cell cultures to sulfur mustard promotes binding of complement C1q: implications for toxicity and medical countermeasures

Journal of applied toxicology, 2000-12, Vol.20 (S1), p.S77-S80

2000

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Activation of alpha-human tumour necrosis factor (TNF-α) by human monocytes (THP-1) exposed to 2-chloroethyl ethyl sulphide (H-MG)

Human & experimental toxicology, 1995-07, Vol.14 (7), p.547-553

1995

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Anticholinesterases: Medical Applications of Neurochemical Principles

Journal of neurochemistry, 1995-05, Vol.64 (5), p.1909-1918

1995

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Progress on the road to new nerve agent treatments

Journal of applied toxicology, 2001-12, Vol.21 (S1), p.S43-S46

2001

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Progress on the road to new nerve agent treatments: Medical Countermeasures for Nerve Agents

Journal of applied toxicology, 2001, Vol.21, p.S43-S46

2001

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Regulation of 1‐α, 25‐Dihydroxyvitamin D3 on Interleukin‐6 and Interleukin‐8 Induced by Sulfur Mustard (HD) on Human Skin Cells

Pharmacology & toxicology, 2003-05, Vol.92 (5), p.204-213

2003

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Protein engineering of a human enzyme that hydrolyzes V and G nerve agents: design, construction and characterization

Chemico-biological interactions, 1999-05, Vol.119-120, p.413-418

1999

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Active site spin-labeled .alpha.-chymotrypsin. Guanidine hydrochloride denaturation studies using electron paramagnetic resonance and circular dichroism

Journal of the American Chemical Society, 1971-12, Vol.93 (26), p.7297-7304

1971

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Cutaneous exposure to bis-(2-chloroethyl)sulfide results in neutrophil infiltration and increased solubility of 180,000 m r subepidermal collagens

Biochemical pharmacology, 1997-05, Vol.53 (10), p.1405-1412

1997

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Expression of biologically active human butyrylcholinesterase in the cabbage looper (Trichoplusia ni)

Biotechnology and applied biochemistry, 2000-06, Vol.31 (3), p.225-229

2000

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Purification and characterization of protease activated by sulfur mustard in normal human epidermal keratinocytes

Biochemical pharmacology, 1998-08, Vol.56 (4), p.467-472

1998

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A computer model of glycosylated human butyrylcholinesterase

Biochemical and biophysical research communications, 1992-12, Vol.189 (3), p.1280-1286

1992

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Plant-derived human butyrylcholinesterase, but not an organophosphorous-compound hydrolyzing variant thereof, protects rodents against nerve agents

Comparison of human and guinea pig acetylcholinesterase sequences and rates of oxime-assisted reactivation

A Single Amino Acid Substitution, Gly117His, Confers Phosphotriesterase (Organophosphorus Acid Anhydride Hydrolase) Activity on Human Butyrylcholinesterase

A collaborative endeavor to design cholinesterase-based catalytic scavengers against toxic organophosphorus esters

Design and expression of organophosphorus acid anhydride hydrolase activity in human butyrylcholinesterase

Response of normal human keratinocytes to sulfur mustard: cytokine release

The effect of the human serum paraoxonase polymorphism is reversed with diazoxon, soman and sarin

Evidence for nonacetylcholinesterase targets of organophosphorus nerve agent: supersensitivity of acetylcholinesterase knockout mouse to VX lethality

Organophosphorus Acid Anhydride Hydrolase Activity in Human Butyrylcholinesterase: Synergy Results in a Somanase

BIOCHEMICAL ALTERATIONS IN RAT LUNG LAVAGE FLUID FOLLOWING ACUTE SULFUR MUSTARD INHALATION: II. INCREASES IN PROTEOLYTIC ACTIVITY

A review of multi-threat medical countermeasures against chemical warfare and terrorism

The Role of Interleukin-6 (IL-6) in Human Sulfur Mustard (HD) Toxicology

Neutralization effects of interleukin-6 (IL-6) antibodies on sulfur mustard (HD)-induced IL-6 secretion on human epidermal keratinocytes

Exposure of human epidermal keratinocyte cell cultures to sulfur mustard promotes binding of complement C1q: implications for toxicity and medical countermeasures

Activation of alpha-human tumour necrosis factor (TNF-α) by human monocytes (THP-1) exposed to 2-chloroethyl ethyl sulphide (H-MG)

Anticholinesterases: Medical Applications of Neurochemical Principles

Progress on the road to new nerve agent treatments

Progress on the road to new nerve agent treatments: Medical Countermeasures for Nerve Agents

Regulation of 1‐α, 25‐Dihydroxyvitamin D3 on Interleukin‐6 and Interleukin‐8 Induced by Sulfur Mustard (HD) on Human Skin Cells

Protein engineering of a human enzyme that hydrolyzes V and G nerve agents: design, construction and characterization

Active site spin-labeled .alpha.-chymotrypsin. Guanidine hydrochloride denaturation studies using electron paramagnetic resonance and circular dichroism

Cutaneous exposure to bis-(2-chloroethyl)sulfide results in neutrophil infiltration and increased solubility of 180,000 m r subepidermal collagens

Expression of biologically active human butyrylcholinesterase in the cabbage looper (Trichoplusia ni)

Purification and characterization of protease activated by sulfur mustard in normal human epidermal keratinocytes

A computer model of glycosylated human butyrylcholinesterase

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