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Molecular Pathways: Fibroblast Growth Factor Signaling: A New Therapeutic Opportunity in Cancer

Clinical cancer research, 2012-04, Vol.18 (7), p.1855-1862

2012

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AZD4547: An Orally Bioavailable, Potent, and Selective Inhibitor of the Fibroblast Growth Factor Receptor Tyrosine Kinase Family

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8), p.2045-2056

2012

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Translating the Therapeutic Potential of AZD4547 in FGFR1-Amplified Non―Small Cell Lung Cancer through the Use of Patient-Derived Tumor Xenograft Models

Clinical cancer research, 2012-12, Vol.18 (24), p.6658-6667

2012

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AZD3514: a small molecule that modulates androgen receptor signaling and function in vitro and in vivo

Molecular cancer therapeutics, 2013-09, Vol.12 (9), p.1715-1727

2013

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Small-molecule androgen receptor downregulators as an approach to treatment of advanced prostate cancer

Bioorganic & medicinal chemistry letters, 2011-09, Vol.21 (18), p.5442-5445

2011

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Discovery of AZD3514, a small-molecule androgen receptor downregulator for treatment of advanced prostate cancer

Bioorganic & medicinal chemistry letters, 2013-04, Vol.23 (7), p.1945-1948

2013

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Neurotrophic effects of BDNF on embryonic gonadotropin-releasing hormone (GnRH) neurons

The European journal of neuroscience, 2004-07, Vol.20 (2), p.338-344

2004

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Estrogenic Induction of Spermatogenesis in the Hypogonadal Mouse

Endocrinology (Philadelphia), 2000-08, Vol.141 (8), p.2861-2869

2000

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Effects of nutrition and environmental factors on the fetal programming of the reproductive axis

Reproduction (Cambridge, England), 2001-08, Vol.122 (2), p.205-214

2001

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Epigenetic silencing of the endothelin-B receptor gene in non-small cell lung cancer

International journal of oncology, 2009-02, Vol.34 (2), p.465-471

2009

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Phytoestrogens and Gonadotropin-Releasing Hormone Pulse Generator Activity and Pituitary Luteinizing Hormone Release in the Rat

Endocrinology (Philadelphia), 2001-03, Vol.142 (3), p.1202-1208

2001

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Abstract DDT01-01: Preclinical profile of AZD4547: A selective inhibitor of FGF-receptors 1, 2, and 3

Cancer research (Chicago, Ill.), 2011-04, Vol.71 (8_Supplement), p.DDT01-01-DDT01-01

Brooks, Nigel A.

2011

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Abstract 3758: Activity of AZD4547, a potent and selective FGF-receptor inhibitor, alone and in combination with chemotherapy in standard xenograft and human primary explant models of FGF-receptor 2 amplified gastric cancer

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8_Supplement), p.3758-3758

2012

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Development of Gonadotrophs and Thyrotrophs in the Female Foetal Sheep Pituitary: Immunocytochemical Localization Studies

Journal of neuroendocrinology, 1993-04, Vol.5 (2), p.157-161

1993

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Abstract 1917: Translating the therapeutic potential of AZD4547 in FGFR1-amplified non-small cell lung cancer through the use of primary lung explant models

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8_Supplement), p.1917-1917

2012

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Maturation and activation of hypothalamic-pituitary-adrenal function in fetal sheep

Endocrine reviews, 1989-05, Vol.10 (2), p.182-204

1989

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Abstract 3568: Characterization of AZD4547: An orally bioavailable, potent and selective inhibitor of FGFR tyrosine kinases 1, 2 and 3

Cancer research (Chicago, Ill.), 2011-04, Vol.71 (8_Supplement), p.3568-3568

2011

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Obstacles to the prediction of estrogenicity from chemical structure: assay-mediated metabolic transformation and the apparent promiscuous nature of the estrogen receptor

Biochemical pharmacology, 2000-11, Vol.60 (10), p.1519-1530

2000

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Estrogenic Induction of Spermatogenesis in the Hypogonadal Mouse1

Endocrinology (Philadelphia), 2000-08, Vol.141 (8), p.2861-2869

2000

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Phytoestrogens and Gonadotropin-Releasing Hormone Pulse Generator Activity and Pituitary Luteinizing Hormone Release in the Rat1

Endocrinology (Philadelphia), 2001-03, Vol.142 (3), p.1202-1208

2001

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Identification of a possible association between carbon tetrachloride-induced hepatotoxicity and interleukin-8 expression

Journal of biochemical and molecular toxicology, 2000, Vol.14 (5), p.283-290

2000

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Leptin Acts on Metabolism in a Photoperiod-Dependent Manner, But Has No Effect on Reproductive Function in the Seasonally Breeding Siberian Hamster (Phodopus sungorus)1

Endocrinology (Philadelphia), 2000-11, Vol.141 (11), p.4128-4135

2000

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Leptin Acts on Metabolism in a Photoperiod-Dependent Manner, But Has No Effect on Reproductive Function in the Seasonally Breeding Siberian Hamster (Phodopus sungorus)This work was supported by a research grant awarded to A.S.I.L. and FRAC by the Biotechnology and Biological Sciences Research Council (United Kingdom) and a Biotechnology and Biological Sciences Research Council-supported Ph.D. studentship (to Z.A.) also supported in part by AstraZeneca Central Toxicology Laboratory (Cheshire, UK)

Endocrinology (Philadelphia), 2000-11, Vol.141 (11), p.4128-4135

2000

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Emergency surgery

1, 2010

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Issues For Financial Services Marketing

The Journal of services marketing, 1987-07, Vol.1 (1), p.57

Brooks, Nigel A L

1987

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Molecular Pathways: Fibroblast Growth Factor Signaling: A New Therapeutic Opportunity in Cancer

AZD4547: An Orally Bioavailable, Potent, and Selective Inhibitor of the Fibroblast Growth Factor Receptor Tyrosine Kinase Family

Translating the Therapeutic Potential of AZD4547 in FGFR1-Amplified Non―Small Cell Lung Cancer through the Use of Patient-Derived Tumor Xenograft Models

AZD3514: a small molecule that modulates androgen receptor signaling and function in vitro and in vivo

Small-molecule androgen receptor downregulators as an approach to treatment of advanced prostate cancer

Discovery of AZD3514, a small-molecule androgen receptor downregulator for treatment of advanced prostate cancer

Neurotrophic effects of BDNF on embryonic gonadotropin-releasing hormone (GnRH) neurons

Estrogenic Induction of Spermatogenesis in the Hypogonadal Mouse

Effects of nutrition and environmental factors on the fetal programming of the reproductive axis

Epigenetic silencing of the endothelin-B receptor gene in non-small cell lung cancer

Phytoestrogens and Gonadotropin-Releasing Hormone Pulse Generator Activity and Pituitary Luteinizing Hormone Release in the Rat

Abstract DDT01-01: Preclinical profile of AZD4547: A selective inhibitor of FGF-receptors 1, 2, and 3

Abstract 3758: Activity of AZD4547, a potent and selective FGF-receptor inhibitor, alone and in combination with chemotherapy in standard xenograft and human primary explant models of FGF-receptor 2 amplified gastric cancer

Development of Gonadotrophs and Thyrotrophs in the Female Foetal Sheep Pituitary: Immunocytochemical Localization Studies

Abstract 1917: Translating the therapeutic potential of AZD4547 in FGFR1-amplified non-small cell lung cancer through the use of primary lung explant models

Maturation and activation of hypothalamic-pituitary-adrenal function in fetal sheep

Abstract 3568: Characterization of AZD4547: An orally bioavailable, potent and selective inhibitor of FGFR tyrosine kinases 1, 2 and 3

Obstacles to the prediction of estrogenicity from chemical structure: assay-mediated metabolic transformation and the apparent promiscuous nature of the estrogen receptor

Estrogenic Induction of Spermatogenesis in the Hypogonadal Mouse1

Phytoestrogens and Gonadotropin-Releasing Hormone Pulse Generator Activity and Pituitary Luteinizing Hormone Release in the Rat1

Identification of a possible association between carbon tetrachloride-induced hepatotoxicity and interleukin-8 expression

Leptin Acts on Metabolism in a Photoperiod-Dependent Manner, But Has No Effect on Reproductive Function in the Seasonally Breeding Siberian Hamster (Phodopus sungorus)1

Emergency surgery

Issues For Financial Services Marketing

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