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Activation of cultured human endothelial cells by recombinant lymphotoxin: comparison with tumor necrosis factor and interleukin 1 species

The Journal of immunology (1950), 1987-05, Vol.138 (10), p.3319

1987

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Cloning of Human Junctional Adhesion Molecule 3 (JAM3) and Its Identification as the JAM2 Counter-receptor

The Journal of biological chemistry, 2001-12, Vol.276 (49), p.45826-45832

2001

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Discovery, Modeling, and Human Pharmacokinetics of N-(2-Acetyl-4,6-dimethylphenyl)-3-(3,4-dimethylisoxazol-5-ylsulfamoyl)thiophene-2-carboxamide (TBC3711), a Second Generation, ETA Selective, and Orally Bioavailable Endothelin Antagonist

Journal of medicinal chemistry, 2004-04, Vol.47 (8), p.1969-1986

2004

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Superoxide and Peroxynitrite in Atherosclerosis

Proceedings of the National Academy of Sciences - PNAS, 1994-02, Vol.91 (3), p.1044-1048

1994

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A novel protein with homology to the junctional adhesion molecule. Characterization of leukocyte interactions

The Journal of biological chemistry, 2000-11, Vol.275 (44), p.34750-34756

2000

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Vascular endothelial growth factor induces EDRF-dependent relaxation in coronary arteries

American journal of physiology. Heart and circulatory physiology, 1993-08, Vol.265 (2), p.H586-H592

1993

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Role for nitric oxide in the hyperpermeability and hemodynamic changes induced by intravenous VEGF

Investigative ophthalmology & visual science, 1999-03, Vol.40 (3), p.689-696

1999

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Vascular dysfunction induced by elevated glucose levels in rats is mediated by vascular endothelial growth factor

The Journal of clinical investigation, 1997-05, Vol.99 (9), p.2192-2202

1997

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Bradycardia-Induced Coronary Angiogenesis Is Dependent on Vascular Endothelial Growth Factor

Circulation research, 1999-07, Vol.85 (2), p.192-198

1999

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Irrigation Water Quality, Soil Amendment, and Crop Effects on Sodium Leaching

Arid Land Research and Management, 2001, Vol.15 (2), p.101-113

2001

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Interaction of the Flt-1 tyrosine kinase receptor with the p85 subunit of phosphatidylinositol 3-kinase. Mapping of a novel site involved in binding

The Journal of biological chemistry, 1995-09, Vol.270 (35), p.20254-20257

1995

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Characterization of vascular endothelial cell growth factor interactions with the kinase insert domain-containing receptor tyrosine kinase. A real time kinetic study

The Journal of biological chemistry, 1999-06, Vol.274 (26), p.18421-18427

1999

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Endothelin action on vascular smooth muscle involves inositol trisphosphate and calcium mobilization

Biochemical and biophysical research communications, 1989-01, Vol.158 (1), p.86-93

1989

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TBC3711, an ETA receptor antagonist, reduces neonatal hypoxia-induced pulmonary hypertension in piglets

Pediatric research, 2001-09, Vol.50 (3), p.374-383

2001

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Interactions of FLT-1 and KDR with Phospholipase C γ: Identification of the Phosphotyrosine Binding Sites

Biochemical and biophysical research communications, 1997-11, Vol.240 (3), p.635-639

1997

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Peroxynitrite stimulates vascular smooth muscle cell cyclic GMP synthesis

FEBS letters, 1995-05, Vol.364 (3), p.314-318

1995

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Acyl Substitution at the Ortho Position of Anilides Enhances Oral Bioavailability of Thiophene Sulfonamides: TBC3214, an ETA Selective Endothelin Antagonist

Journal of medicinal chemistry, 2001-04, Vol.44 (8), p.1211-1216

2001

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Therapeutic potential of endothelin receptor antagonists and nitric oxide donors in pulmonary hypertension

Expert opinion on investigational drugs, 2001-07, Vol.10 (7), p.1291-1308

2001

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Sustained diacylglycerol formation from inositol phospholipids in angiotensin II-stimulated vascular smooth muscle cells

The Journal of biological chemistry, 1986-05, Vol.261 (13), p.5901-5906

1986

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Vasoconstriction: A New Activity for Platelet-Derived Growth Factor

Science (American Association for the Advancement of Science), 1986-04, Vol.232 (4746), p.87-90

1986

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Glomerular endothelial cells respond to calcium-mobilizing agonists with release of EDRF

American journal of physiology. Renal physiology, 1990-05, Vol.258 (5), p.1295-F1303

1990

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Thrombin and histamine activate phospholipase C in human endothelial cells via a phorbol ester-sensitive pathway

Journal of cellular physiology, 1988-07, Vol.136 (1), p.54-62

1988

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Endothelin receptor-coupling mechanisms in vascular smooth muscle: a role for protein kinase C

The Journal of pharmacology and experimental therapeutics, 1990-08, Vol.254 (2), p.393

1990

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Endothelin Antagonists: Substituted Mesitylcarboxamides with High Potency and Selectivity for ETA Receptors

Journal of medicinal chemistry, 1999-11, Vol.42 (22), p.4485-4499

1999

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Early agonist-mediated ionic events in cultured vascular smooth muscle cells. Calcium mobilization is associated with intracellular acidification

The Journal of biological chemistry, 1987-04, Vol.262 (11), p.5065-5072

1987

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Activation of cultured human endothelial cells by recombinant lymphotoxin: comparison with tumor necrosis factor and interleukin 1 species

Cloning of Human Junctional Adhesion Molecule 3 (JAM3) and Its Identification as the JAM2 Counter-receptor

Discovery, Modeling, and Human Pharmacokinetics of N-(2-Acetyl-4,6-dimethylphenyl)-3-(3,4-dimethylisoxazol-5-ylsulfamoyl)thiophene-2-carboxamide (TBC3711), a Second Generation, ETA Selective, and Orally Bioavailable Endothelin Antagonist

Superoxide and Peroxynitrite in Atherosclerosis

A novel protein with homology to the junctional adhesion molecule. Characterization of leukocyte interactions

Vascular endothelial growth factor induces EDRF-dependent relaxation in coronary arteries

Role for nitric oxide in the hyperpermeability and hemodynamic changes induced by intravenous VEGF

Vascular dysfunction induced by elevated glucose levels in rats is mediated by vascular endothelial growth factor

Bradycardia-Induced Coronary Angiogenesis Is Dependent on Vascular Endothelial Growth Factor

Irrigation Water Quality, Soil Amendment, and Crop Effects on Sodium Leaching

Interaction of the Flt-1 tyrosine kinase receptor with the p85 subunit of phosphatidylinositol 3-kinase. Mapping of a novel site involved in binding

Characterization of vascular endothelial cell growth factor interactions with the kinase insert domain-containing receptor tyrosine kinase. A real time kinetic study

Endothelin action on vascular smooth muscle involves inositol trisphosphate and calcium mobilization

TBC3711, an ETA receptor antagonist, reduces neonatal hypoxia-induced pulmonary hypertension in piglets

Interactions of FLT-1 and KDR with Phospholipase C γ: Identification of the Phosphotyrosine Binding Sites

Peroxynitrite stimulates vascular smooth muscle cell cyclic GMP synthesis

Acyl Substitution at the Ortho Position of Anilides Enhances Oral Bioavailability of Thiophene Sulfonamides: TBC3214, an ETA Selective Endothelin Antagonist

Therapeutic potential of endothelin receptor antagonists and nitric oxide donors in pulmonary hypertension

Sustained diacylglycerol formation from inositol phospholipids in angiotensin II-stimulated vascular smooth muscle cells

Vasoconstriction: A New Activity for Platelet-Derived Growth Factor

Glomerular endothelial cells respond to calcium-mobilizing agonists with release of EDRF

Thrombin and histamine activate phospholipase C in human endothelial cells via a phorbol ester-sensitive pathway

Endothelin receptor-coupling mechanisms in vascular smooth muscle: a role for protein kinase C

Endothelin Antagonists: Substituted Mesitylcarboxamides with High Potency and Selectivity for ETA Receptors

Early agonist-mediated ionic events in cultured vascular smooth muscle cells. Calcium mobilization is associated with intracellular acidification

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