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Discovery of a brain penetrant small molecule antagonist targeting LPA1 receptors to reduce neuroinflammation and promote remyelination in multiple sclerosis

Scientific reports, 2024-05, Vol.14 (1), p.10573-10573, Article 10573

2024

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Pharmacokinetic and pharmacodynamic characterization of an oral lysophosphatidic acid type 1 receptor-selective antagonist

The Journal of pharmacology and experimental therapeutics, 2011-03, Vol.336 (3), p.693

2011

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Increasing drug users’ adherence to HIV treatment: results of a peer-driven intervention feasibility study

Social science & medicine (1982), 2002-07, Vol.55 (2), p.235-246

2002

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Bacterial vaginosis and disturbances of vaginal flora : association with increased acquisition of HIV

AIDS (London), 1998-09, Vol.12 (13), p.1699-1706

1998

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Therapeutic efficacy of AM156, a novel prostanoid DP2 receptor antagonist, in murine models of allergic rhinitis and house dust mite-induced pulmonary inflammation

European journal of pharmacology, 2010-07, Vol.638 (1-3), p.142-149

2010

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Childhood tuberculosis in Malawi: nationwide case-finding and treatment outcomes

The international journal of tuberculosis and lung disease, 2002-05, Vol.6 (5), p.424

2002

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Pharmacological blockade of the DP2 receptor inhibits cigarette smoke-induced inflammation, mucus cell metaplasia, and epithelial hyperplasia in the mouse lung

The Journal of pharmacology and experimental therapeutics, 2010-03, Vol.332 (3), p.764

2010

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Harnessing Peer Networks as an Instrument for AIDS Prevention: Results from a Peer-Driven Intervention

Public health reports (1974), 1998-06, Vol.113 (Suppl 1), p.42-57

1998

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Exploring the potential linkages between oil‐field brine reinjection, crystalline basement permeability, and triggered seismicity for the Dagger Draw Oil field, southeastern New Mexico, USA, using hydrologic modeling

Geofluids, 2016-12, Vol.16 (5), p.971-987

2016

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Spectrum and presentation of pediatric malignancies in the HIV era: Experience from Blantyre, Malawi, 1998-2003

Pediatric Blood & Cancer, 2007-05, Vol.48 (5), p.515-520

2007

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Nevirapine and zidovudine at birth to reduce perinatal transmission of HIV in an African setting: a randomized controlled trial

JAMA : the journal of the American Medical Association, 2004-07, Vol.292 (2), p.202

2004

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Placental antibody transfer: influence of maternal HIV infection and placental malaria

Archives of disease in childhood. Fetal and neonatal edition, 1998-11, Vol.79 (3), p.F202

1998

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Rotavirus G and P types in children with acute diarrhea in Blantyre, Malawi, from 1997 to 1998: Predominance of novel P[6]G8 Strains

Journal of medical virology, 1999-03, Vol.57 (3), p.308-312

1999

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Increased prevalence of malaria in HIV‐infected pregnant women and its implications for malaria control

Tropical medicine & international health, 1999-01, Vol.4 (1), p.5-12

1999

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Morbidity among human immunodeficiency virus-1-infected and -uninfected African children

Pediatrics (Evanston), 2000-12, Vol.106 (6), p.E77

2000

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In vitro and in vivo pharmacology of NXT629, a novel and selective PPARα antagonist

European journal of pharmacology, 2017-08, Vol.809, p.130-140

2017

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An analysis of intra-uterine growth retardation in rural Malawi

European journal of clinical nutrition, 2001-08, Vol.55 (8), p.682-689

2001

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Pharmacological characterization of 3-[3-tert-butylsulfanyl-1-[4-(6-methoxy-pyridin-3-yl)-benzyl]-5-(pyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethyl-propionic acid (AM103), a novel selective 5-lipoxygenase-activating protein inhibitor that reduces acute and chronic inflammation

The Journal of pharmacology and experimental therapeutics, 2009-12, Vol.331 (3), p.1042

2009

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Endemic Burkitt lymphoma: a 28-day treatment schedule with cyclophosphamide and intrathecal methotrexate

Annals of tropical paediatrics, 2009-03, Vol.29 (1), p.29-34

2009

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Rescue chemotherapy for patients with resistant or relapsed endemic Burkitt's lymphoma

Transactions of the Royal Society of Tropical Medicine and Hygiene, 2008-06, Vol.102 (6), p.602-607

2008

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Detection and Characterization of Rotaviruses in Hospitalized Neonates in Blantyre, Malawi

Journal of Clinical Microbiology, 2002-04, Vol.40 (4), p.1534-1537

2002

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Risk factors for fetal anaemia in a malarious area of Malawi

Annals of tropical paediatrics, 2004-12, Vol.24 (4), p.311-321

2004

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Epidemiology of measles in Blantyre, Malawi: analyses of passive surveillance data from 1996 to 1998

Epidemiology and infection, 2002-10, Vol.129 (2), p.361-369, Article 361

2002

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Promiscuous expression of Epstein‐Barr virus genes in Burkitt's lymphoma from the central African country Malawi

International journal of cancer, 2002-06, Vol.99 (5), p.635-643

2002

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Flagellar motility is required for the viability of the bloodstream trypanosome

Nature, 2006-03, Vol.440 (7081), p.224-227

2006

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Discovery of a brain penetrant small molecule antagonist targeting LPA1 receptors to reduce neuroinflammation and promote remyelination in multiple sclerosis

Pharmacokinetic and pharmacodynamic characterization of an oral lysophosphatidic acid type 1 receptor-selective antagonist

Increasing drug users’ adherence to HIV treatment: results of a peer-driven intervention feasibility study

Bacterial vaginosis and disturbances of vaginal flora : association with increased acquisition of HIV

Therapeutic efficacy of AM156, a novel prostanoid DP2 receptor antagonist, in murine models of allergic rhinitis and house dust mite-induced pulmonary inflammation

Childhood tuberculosis in Malawi: nationwide case-finding and treatment outcomes

Pharmacological blockade of the DP2 receptor inhibits cigarette smoke-induced inflammation, mucus cell metaplasia, and epithelial hyperplasia in the mouse lung

Harnessing Peer Networks as an Instrument for AIDS Prevention: Results from a Peer-Driven Intervention

Exploring the potential linkages between oil‐field brine reinjection, crystalline basement permeability, and triggered seismicity for the Dagger Draw Oil field, southeastern New Mexico, USA, using hydrologic modeling

Spectrum and presentation of pediatric malignancies in the HIV era: Experience from Blantyre, Malawi, 1998-2003

Nevirapine and zidovudine at birth to reduce perinatal transmission of HIV in an African setting: a randomized controlled trial

Placental antibody transfer: influence of maternal HIV infection and placental malaria

Rotavirus G and P types in children with acute diarrhea in Blantyre, Malawi, from 1997 to 1998: Predominance of novel P[6]G8 Strains

Increased prevalence of malaria in HIV‐infected pregnant women and its implications for malaria control

Morbidity among human immunodeficiency virus-1-infected and -uninfected African children

In vitro and in vivo pharmacology of NXT629, a novel and selective PPARα antagonist

An analysis of intra-uterine growth retardation in rural Malawi

Pharmacological characterization of 3-[3-tert-butylsulfanyl-1-[4-(6-methoxy-pyridin-3-yl)-benzyl]-5-(pyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethyl-propionic acid (AM103), a novel selective 5-lipoxygenase-activating protein inhibitor that reduces acute and chronic inflammation

Endemic Burkitt lymphoma: a 28-day treatment schedule with cyclophosphamide and intrathecal methotrexate

Rescue chemotherapy for patients with resistant or relapsed endemic Burkitt's lymphoma

Detection and Characterization of Rotaviruses in Hospitalized Neonates in Blantyre, Malawi

Risk factors for fetal anaemia in a malarious area of Malawi

Epidemiology of measles in Blantyre, Malawi: analyses of passive surveillance data from 1996 to 1998

Promiscuous expression of Epstein‐Barr virus genes in Burkitt's lymphoma from the central African country Malawi

Flagellar motility is required for the viability of the bloodstream trypanosome

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