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Substituted Hexahydrobenzo[f]thieno[c]quinolines as Dopamine D1-Selective Agonists: Synthesis and Biological Evaluation in Vitro and in Vivo

Journal of medicinal chemistry, 1997-05, Vol.40 (11), p.1585-1599

1997

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Synthesis and dopaminergic activity of 3-substituted 1-(aminomethyl)-3,4-dihydro-5,6-dihydroxy-1H-2-benzopyrans: characterization of an auxiliary binding region in the D1 receptor

Journal of medicinal chemistry, 1991-08, Vol.34 (8), p.2561-2569

1991

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Hyperactivity and behavioral seizures in rodents following treatment with the dopamine D1 receptor agonists A-86929 and ABT-431

European journal of pharmacology, 1996-12, Vol.317 (2-3), p.183-190

1996

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Synthesis and pharmacological evaluation of 1-(aminomethyl)-3,4-dihydro-5-hydroxy-1H-2-benzopyrans as dopamine D1 selective ligands

Journal of medicinal chemistry, 1991-10, Vol.34 (10), p.2946-2953

1991

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(5aR,11bS)-4,5,5a,6,7,11b-Hexahydro-2-propyl-3-thia-5-azacyclopent-1-ena[c]phenanthrene-9,10-diol (A-86929): a potent and selective dopamine D1 agonist that maintain behavioral efficacy following repeated administration and characterization of its diacetyl prodrug (ABT-431)

Journal of medicinal chemistry, 1995-09, Vol.38 (18), p.3445-3447

1995

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Potential therapeutic use of the selective dopamine D1 receptor agonist, A-86929: an acute study in parkinsonian levodopa-primed monkeys

Neurology, 1997-08, Vol.49 (2), p.421

1997

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A comparison of the behavioral effects of CRF, sauvagine and urotensin I

Brain research, 1984-06, Vol.304 (2), p.201-205

1984

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A-77636 : a potent and selective dopamine D1 receptor agonist with antiparkinsonian activity in marmosets

European journal of pharmacology, 1992-12, Vol.229 (2-3), p.203-209

1992

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Site and event specific increase of striatal adenosine release by adenosine kinase inhibition in rats

Neuroscience letters, 1999-05, Vol.266 (2), p.93-96

1999

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Dopamine D1 receptor desensitization profile in MPTP-lesioned primates

European journal of pharmacology, 1996-08, Vol.309 (1), p.13-20

1996

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(5aR,11bS)-4,5,5a,6,7,11b-hexahydro-2-propyl-3-thia-5-azacyclopent-1-ena[c]-phenanthrene-9,10-diol (A-86929) : a potent and selective dopamine D1 agonist that maintains behavioral efficacy following repeated administration and characterization of its diacetyl prodrug (ABT-431)

Journal of medicinal chemistry, 1995-09, Vol.38 (18), p.3445-3447

1995

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Dopamine D 1 receptor desensitization profile in MPTP-lesioned primates

European journal of pharmacology, 1996-08, Vol.309 (1), p.13-20

1996

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ABT-431: the diacetyl prodrug of A-86929, a potent and selective dopamine D1 receptor agonist: in vitro characterization and effects in animal models of Parkinson's disease

The Journal of pharmacology and experimental therapeutics, 1996-01, Vol.276 (1), p.150

1996

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Persistent activation of the dopamine D1 receptor contributes to prolonged receptor desensitization: studies with A-77636

The Journal of pharmacology and experimental therapeutics, 1996-03, Vol.276 (3), p.1022

1996

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A sensitive open field measure of anxiolytic drug activity

Pharmacology, biochemistry and behavior, 1981-01, Vol.15 (4), p.577-582

1981

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A68930: a potent agonist selective for the dopamine D1 receptor

European journal of pharmacology, 1991-06, Vol.199 (2), p.209-219

1991

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Hyperactivity and behavioral seizures in rodents following treatment with the dopamine D 1 receptor agonists A-86929 and ABT-431

European journal of pharmacology, 1996-12, Vol.317 (2), p.183-190

1996

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Effects of ganglionic blocking agents on behavioral responses to centrally administered CRF

Brain research, 1989-01, Vol.478 (2), p.205-210

1989

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Effects of 5-HT-1A receptor agonists on CRF-induced behavior

Psychopharmacologia, 1991-01, Vol.104 (1), p.132-136

1991

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Central effects of corticotropin releasing factor (CRF): evidence for similar interactions with environmental novelty and with caffeine

Psychopharmacology, 1990-01, Vol.101 (3), p.366-370

1990

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A68930 : a potent agonist specific for the dopamine D1 receptor

Neurochemistry international, 1992-03, Vol.20 (MAR), p.157S-160S

1992

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A68930: A potent agonist specific for the dopamine D 1 receptor

Neurochemistry international, 1992, Vol.20, p.157-160

1992

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Destruction of the locus coeruleus or the dorsal NE bundle does not alter the release of punished responding by ethanol and chlordiazepoxide

Physiology & behavior, 1984-01, Vol.33 (3), p.479-485

1984

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A-77636: a potent and selective dopamine D 1 receptor agonist with antiparkinsonian activity in marmosets

European journal of pharmacology, 1992, Vol.229 (2), p.203-209

1992

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A68930: a potent agonist selective for the dopamine D 1 receptor

European journal of pharmacology, 1991, Vol.199 (2), p.209-219

1991

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Substituted Hexahydrobenzo[f]thieno[c]quinolines as Dopamine D1-Selective Agonists: Synthesis and Biological Evaluation in Vitro and in Vivo

Synthesis and dopaminergic activity of 3-substituted 1-(aminomethyl)-3,4-dihydro-5,6-dihydroxy-1H-2-benzopyrans: characterization of an auxiliary binding region in the D1 receptor

Hyperactivity and behavioral seizures in rodents following treatment with the dopamine D1 receptor agonists A-86929 and ABT-431

Synthesis and pharmacological evaluation of 1-(aminomethyl)-3,4-dihydro-5-hydroxy-1H-2-benzopyrans as dopamine D1 selective ligands

(5aR,11bS)-4,5,5a,6,7,11b-Hexahydro-2-propyl-3-thia-5-azacyclopent-1-ena[c]phenanthrene-9,10-diol (A-86929): a potent and selective dopamine D1 agonist that maintain behavioral efficacy following repeated administration and characterization of its diacetyl prodrug (ABT-431)

Potential therapeutic use of the selective dopamine D1 receptor agonist, A-86929: an acute study in parkinsonian levodopa-primed monkeys

A comparison of the behavioral effects of CRF, sauvagine and urotensin I

A-77636 : a potent and selective dopamine D1 receptor agonist with antiparkinsonian activity in marmosets

Site and event specific increase of striatal adenosine release by adenosine kinase inhibition in rats

Dopamine D1 receptor desensitization profile in MPTP-lesioned primates

(5aR,11bS)-4,5,5a,6,7,11b-hexahydro-2-propyl-3-thia-5-azacyclopent-1-ena[c]-phenanthrene-9,10-diol (A-86929) : a potent and selective dopamine D1 agonist that maintains behavioral efficacy following repeated administration and characterization of its diacetyl prodrug (ABT-431)

Dopamine D 1 receptor desensitization profile in MPTP-lesioned primates

ABT-431: the diacetyl prodrug of A-86929, a potent and selective dopamine D1 receptor agonist: in vitro characterization and effects in animal models of Parkinson's disease

Persistent activation of the dopamine D1 receptor contributes to prolonged receptor desensitization: studies with A-77636

A sensitive open field measure of anxiolytic drug activity

A68930: a potent agonist selective for the dopamine D1 receptor

Hyperactivity and behavioral seizures in rodents following treatment with the dopamine D 1 receptor agonists A-86929 and ABT-431

Effects of ganglionic blocking agents on behavioral responses to centrally administered CRF

Effects of 5-HT-1A receptor agonists on CRF-induced behavior

Central effects of corticotropin releasing factor (CRF): evidence for similar interactions with environmental novelty and with caffeine

A68930 : a potent agonist specific for the dopamine D1 receptor

A68930: A potent agonist specific for the dopamine D 1 receptor

Destruction of the locus coeruleus or the dorsal NE bundle does not alter the release of punished responding by ethanol and chlordiazepoxide

A-77636: a potent and selective dopamine D 1 receptor agonist with antiparkinsonian activity in marmosets

A68930: a potent agonist selective for the dopamine D 1 receptor

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