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G2 checkpoint abrogation and checkpoint kinase-1 targeting in the treatment of cancer

British journal of cancer, 2008-02, Vol.98 (3), p.523-528

2008

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Selective uptake of naked vaccine RNA by dendritic cells is driven by macropinocytosis and abrogated upon DC maturation

Gene therapy, 2011-07, Vol.18 (7), p.702-708

2011

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T Cell Assays and MIATA: The Essential Minimum for Maximum Impact

Immunity (Cambridge, Mass.), 2012-07, Vol.37 (1), p.1-2

2012

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Translation of genomics-guided RNA-based personalised cancer vaccines: towards the bedside

British journal of cancer, 2014-10, Vol.111 (8), p.1469-1475

2014

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Phase I and Pharmacologic Study of OSI-774, an Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor, in Patients With Advanced Solid Malignancies

Journal of clinical oncology, 2001-07, Vol.19 (13), p.3267-3279

2001

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Improving the efficacy of cancer immunotherapy

European Journal of Cancer, 2009-05, Vol.45 (8), p.1424-1431

2009

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Results and harmonization guidelines from two large-scale international Elispot proficiency panels conducted by the Cancer Vaccine Consortium (CVC/SVI)

Cancer Immunology, Immunotherapy, 2008-03, Vol.57 (3), p.303-315

2008

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Phase I/IIa trial of the mammalian target of rapamycin inhibitor ridaforolimus (AP23573; MK-8669) administered orally in patients with refractory or advanced malignancies and sarcoma

Annals of oncology, 2013-04, Vol.24 (4), p.1104-1111

2013

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The CIMT-monitoring panel: a two-step approach to harmonize the enumeration of antigen-specific CD8+ T lymphocytes by structural and functional assays

Cancer Immunology, Immunotherapy, 2008-03, Vol.57 (3), p.289-302

2008

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Minimal information about T cell assays: the process of reaching the community of T cell immunologists in cancer and beyond

Cancer Immunology, Immunotherapy, 2011-01, Vol.60 (1), p.15-22

2011

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Toward the harmonization of immune monitoring in clinical trials: Quo vadis?

Cancer Immunology, Immunotherapy, 2008-03, Vol.57 (3), p.285-288

2008

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Serum is not required for ex vivo IFN-γ ELISPOT: a collaborative study of different protocols from the European CIMT Immunoguiding Program

Cancer Immunology, Immunotherapy, 2010-04, Vol.59 (4), p.619-627

2010

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526 A Phase I study of the dual, intravenous (IV) phosphatidylinositol 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) inhibitor PF-05212384 in combination with irinotecan in patients (pts) with colorectal cancer (CRC) and other advanced solid tumors

European journal of cancer (1990), 2014-11, Vol.50, p.171-171

2014

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Performance of serum-supplemented and serum-free media in IFNγ Elispot Assays for human T cells

Cancer Immunology, Immunotherapy, 2010-04, Vol.59 (4), p.609-618

2010

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366 Phase I Dose-escalation Study of the Oral Dual MTOR/PI3K Inhibitor BEZ235, Solid Dispersion System (SDS) Sachet Formulation, in Patients with Advanced Solid Tumors

European journal of cancer (1990), 2012-11, Vol.48, p.112-112

2012

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Common variants of the TCF7L2 gene are associated with increased risk of type 2 diabetes mellitus in a UK-resident South Asian population

BMC medical genetics, 2008-02, Vol.9 (1), p.8-8

2008

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The promoter polymorphism -232C/G of the PCK1 gene is associated with type 2 diabetes in a UK-resident South Asian population

BMC medical genetics, 2009-09, Vol.10 (1), p.83-83, Article 83

2009

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358 A Multi-arm Phase 1 Dose Escalation Study of Safety, Pharmacokinetics, and Pharmacodynamics of the Dual PI3K/mTOR Inhibitors PF-04691502 (oral) and PF-05212384 (IV) in Combination with the MEK Inhibitor PD-0325901 or Irinotecan in Patients with Advanced Cancer

European journal of cancer (1990), 2012-11, Vol.48, p.109-109

2012

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Effective induction of anti-melanoma immunity following genetic vaccination with synthetic mRNA coding for the fusion protein EGFP.TRP2

Cancer Immunology, Immunotherapy, 2006-03, Vol.55 (3), p.246-253

2006

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A Phase I and Pharmacokinetic Study of the Mitochondrial-specific Rhodacyanine Dye Analog MKT 077

Clinical cancer research, 2000-01, Vol.6 (1), p.42-49

2000

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Preoperative autologous blood donation for bone marrow harvests: Are we wasting donors' time and blood?

Transfusion medicine (Oxford, England), 2006-02, Vol.16 (1), p.57-62

2006

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1001MO Initial safety, pharmacokinetics, and anti-tumor activity data of TCER IMA401, a MAGEA4/8-directed half-life extended TCR bispecific, in phase I dose escalation

Annals of oncology, 2024-09, Vol.35, p.S681-S682

2024

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A Phase I and Pharmacological Study of the Farnesyl Protein Transferase Inhibitor L-778,123 in Patients with Solid Malignancies

Clinical cancer research, 2001-12, Vol.7 (12), p.3894-3903

2001

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Plasma Biomarkers as Predictors of Outcome in Patients with Advanced Hepatocellular Carcinoma

Clinical cancer research, 2012-04, Vol.18 (8), p.2290-2300

2012

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Sorafenib in Advanced Hepatocellular Carcinoma

The New England journal of medicine, 2008-07, Vol.359 (4), p.378-390

2008

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G2 checkpoint abrogation and checkpoint kinase-1 targeting in the treatment of cancer

Selective uptake of naked vaccine RNA by dendritic cells is driven by macropinocytosis and abrogated upon DC maturation

T Cell Assays and MIATA: The Essential Minimum for Maximum Impact

Translation of genomics-guided RNA-based personalised cancer vaccines: towards the bedside

Phase I and Pharmacologic Study of OSI-774, an Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor, in Patients With Advanced Solid Malignancies

Improving the efficacy of cancer immunotherapy

Results and harmonization guidelines from two large-scale international Elispot proficiency panels conducted by the Cancer Vaccine Consortium (CVC/SVI)

Phase I/IIa trial of the mammalian target of rapamycin inhibitor ridaforolimus (AP23573; MK-8669) administered orally in patients with refractory or advanced malignancies and sarcoma

The CIMT-monitoring panel: a two-step approach to harmonize the enumeration of antigen-specific CD8+ T lymphocytes by structural and functional assays

Minimal information about T cell assays: the process of reaching the community of T cell immunologists in cancer and beyond

Toward the harmonization of immune monitoring in clinical trials: Quo vadis?

Serum is not required for ex vivo IFN-γ ELISPOT: a collaborative study of different protocols from the European CIMT Immunoguiding Program

526 A Phase I study of the dual, intravenous (IV) phosphatidylinositol 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) inhibitor PF-05212384 in combination with irinotecan in patients (pts) with colorectal cancer (CRC) and other advanced solid tumors

Performance of serum-supplemented and serum-free media in IFNγ Elispot Assays for human T cells

366 Phase I Dose-escalation Study of the Oral Dual MTOR/PI3K Inhibitor BEZ235, Solid Dispersion System (SDS) Sachet Formulation, in Patients with Advanced Solid Tumors

Common variants of the TCF7L2 gene are associated with increased risk of type 2 diabetes mellitus in a UK-resident South Asian population

The promoter polymorphism -232C/G of the PCK1 gene is associated with type 2 diabetes in a UK-resident South Asian population

358 A Multi-arm Phase 1 Dose Escalation Study of Safety, Pharmacokinetics, and Pharmacodynamics of the Dual PI3K/mTOR Inhibitors PF-04691502 (oral) and PF-05212384 (IV) in Combination with the MEK Inhibitor PD-0325901 or Irinotecan in Patients with Advanced Cancer

Effective induction of anti-melanoma immunity following genetic vaccination with synthetic mRNA coding for the fusion protein EGFP.TRP2

A Phase I and Pharmacokinetic Study of the Mitochondrial-specific Rhodacyanine Dye Analog MKT 077

Preoperative autologous blood donation for bone marrow harvests: Are we wasting donors' time and blood?

1001MO Initial safety, pharmacokinetics, and anti-tumor activity data of TCER IMA401, a MAGEA4/8-directed half-life extended TCR bispecific, in phase I dose escalation

A Phase I and Pharmacological Study of the Farnesyl Protein Transferase Inhibitor L-778,123 in Patients with Solid Malignancies

Plasma Biomarkers as Predictors of Outcome in Patients with Advanced Hepatocellular Carcinoma

Sorafenib in Advanced Hepatocellular Carcinoma

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