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Practical Applications of NMR to Solve Real-World Problems

Molecules (Basel, Switzerland), 2021-11, Vol.26 (23), p.7091

Brinson, Robert G.

2021

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Highly conserved s2m element of SARS-CoV-2 dimerizes via a kissing complex and interacts with host miRNA-1307-3p

Nucleic acids research, 2022-01, Vol.50 (2), p.1017-1032

2022

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2D J-correlated proton NMR experiments for structural fingerprinting of biotherapeutics

Journal of magnetic resonance (1997), 2019-10, Vol.307, p.106581-106581, Article 106581

2019

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Precision and robustness of 2D-NMR for structure assessment of filgrastim biosimilars

Nature biotechnology, 2016-02, Vol.34 (2), p.139-141

2016

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Correlated analytical and functional evaluation of higher order structure perturbations from oxidation of NISTmAb

mAbs, 2023, Vol.15 (1), p.2160227

2023

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Principal component analysis for automated classification of 2D spectra and interferograms of protein therapeutics: influence of noise, reconstruction details, and data preparation

Journal of biomolecular NMR, 2020-11, Vol.74 (10-11), p.643-656

2020

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Backbone NMR assignment of the yeast expressed Fab fragment of the NISTmAb reference antibody

Biomolecular NMR assignments, 2023-06, Vol.17 (1), p.75-81

2023

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Structural Fingerprinting of Antisense Oligonucleotide Therapeutics by Solution NMR Spectroscopy

Pharmaceutical research, 2023-06, Vol.40 (6), p.1373-1382

2023

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Structure and Dynamics of a Site-Specific Labeled Fc Fragment with Altered Effector Functions

Pharmaceutics, 2019-10, Vol.11 (10), p.546

2019

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Grand Challenges in Pharmaceutical Research Series: Ridding the Cold Chain for Biologics

Pharmaceutical research, 2021, Vol.38 (1), p.3-7

2021

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Interlaboratory Studies Using the NISTmAb to Advance Biopharmaceutical Structural Analytics

Frontiers in molecular biosciences, 2022-05, Vol.9, p.876780-876780

2022

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Structural Characterization of the Viral and cRNA Panhandle Motifs from the Infectious Salmon Anemia Virus

Journal of Virology, 2011-12, Vol.85 (24), p.13398-13408

2011

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Hydrogen–Deuterium Exchange Dynamics of NISTmAb Measured by Small Angle Neutron Scattering

Molecular pharmaceutics, 2023-12, Vol.20 (12), p.6358-6367

2023

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Best Practices in Utilization of 2D-NMR Spectral Data as the Input for Chemometric Analysis in Biopharmaceutical Applications

Journal of chemical information and modeling, 2020-04, Vol.60 (4), p.2339-2355

2020

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Excipient Innovation Through Precompetitive Research

Pharmaceutical research, 2021-12, Vol.38 (12), p.2179-2184

2021

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2D (1)H(N), (15)N Correlated NMR Methods at Natural Abundance for Obtaining Structural Maps and Statistical Comparability of Monoclonal Antibodies

Pharmaceutical research, 2016-02, Vol.33 (2), p.462-475

2016

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Structural Fingerprinting of siRNA Therapeutics by Solution NMR Spectroscopy

Nucleic acid therapeutics, 2022-08, Vol.32 (4), p.267-279

2022

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Enabling adoption of 2D-NMR for the higher order structure assessment of monoclonal antibody therapeutics

mAbs, 2019-01, Vol.11 (1), p.94-105

2019

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Characterization of the internal translation initiation region in monoclonal antibodies expressed in Escherichia coli

The Journal of biological chemistry, 2019-11, Vol.294 (48), p.18046-18056

2019

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Structural insights into DNA-stabilized silver clusters

Soft matter, 2019-05, Vol.15 (21), p.4284-4293

2019

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Chemometric outlier classification of 2D-NMR spectra to enable higher order structure characterization of protein therapeutics

Chemometrics and intelligent laboratory systems, 2020-04, Vol.199, p.103973, Article 103973

2020

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Crystal Structure of a Bivalent Antibody Fab Fragment

Journal of molecular biology, 2021-01, Vol.433 (2), p.166714, Article 166714

2021

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Platform development for expression and purification of stable isotope labeled monoclonal antibodies in Escherichia coli

mAbs, 2018-10, Vol.10 (7), p.992-11

2018

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Assessment of the Higher‐Order Structure of Formulated Monoclonal Antibody Therapeutics by 2D Methyl Correlated NMR and Principal Component Analysis

Current Protocols in Protein Science, 2020-06, Vol.100 (1), p.e105-n/a

2020

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Application of Natural Isotopic Abundance ¹H-¹³C- and ¹H-¹⁵N-Correlated Two-Dimensional NMR for Evaluation of the Structure of Protein Therapeutics

Methods in enzymology, 2016, Vol.566, p.3-34

2016

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Practical Applications of NMR to Solve Real-World Problems

Highly conserved s2m element of SARS-CoV-2 dimerizes via a kissing complex and interacts with host miRNA-1307-3p

2D J-correlated proton NMR experiments for structural fingerprinting of biotherapeutics

Precision and robustness of 2D-NMR for structure assessment of filgrastim biosimilars

Correlated analytical and functional evaluation of higher order structure perturbations from oxidation of NISTmAb

Principal component analysis for automated classification of 2D spectra and interferograms of protein therapeutics: influence of noise, reconstruction details, and data preparation

Backbone NMR assignment of the yeast expressed Fab fragment of the NISTmAb reference antibody

Structural Fingerprinting of Antisense Oligonucleotide Therapeutics by Solution NMR Spectroscopy

Structure and Dynamics of a Site-Specific Labeled Fc Fragment with Altered Effector Functions

Grand Challenges in Pharmaceutical Research Series: Ridding the Cold Chain for Biologics

Interlaboratory Studies Using the NISTmAb to Advance Biopharmaceutical Structural Analytics

Structural Characterization of the Viral and cRNA Panhandle Motifs from the Infectious Salmon Anemia Virus

Hydrogen–Deuterium Exchange Dynamics of NISTmAb Measured by Small Angle Neutron Scattering

Best Practices in Utilization of 2D-NMR Spectral Data as the Input for Chemometric Analysis in Biopharmaceutical Applications

Excipient Innovation Through Precompetitive Research

2D (1)H(N), (15)N Correlated NMR Methods at Natural Abundance for Obtaining Structural Maps and Statistical Comparability of Monoclonal Antibodies

Structural Fingerprinting of siRNA Therapeutics by Solution NMR Spectroscopy

Enabling adoption of 2D-NMR for the higher order structure assessment of monoclonal antibody therapeutics

Characterization of the internal translation initiation region in monoclonal antibodies expressed in Escherichia coli

Structural insights into DNA-stabilized silver clusters

Chemometric outlier classification of 2D-NMR spectra to enable higher order structure characterization of protein therapeutics

Crystal Structure of a Bivalent Antibody Fab Fragment

Platform development for expression and purification of stable isotope labeled monoclonal antibodies in Escherichia coli

Assessment of the Higher‐Order Structure of Formulated Monoclonal Antibody Therapeutics by 2D Methyl Correlated NMR and Principal Component Analysis

Application of Natural Isotopic Abundance ¹H-¹³C- and ¹H-¹⁵N-Correlated Two-Dimensional NMR for Evaluation of the Structure of Protein Therapeutics

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