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Epitope spreading toward wild-type melanocyte-lineage antigens rescues suboptimal immune checkpoint blockade responses

Science translational medicine, 2021-02, Vol.13 (581)

2021

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A TLR7 agonist strengthens T and NK cell function during BRAF‐targeted therapy in a preclinical melanoma model

International journal of cancer, 2020-03, Vol.146 (5), p.1409-1420

2020

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Cancer Stem Cells (CSCs) in melanoma: There's smoke, but is there fire?

Journal of cellular physiology, 2017-10, Vol.232 (10), p.2674-2678

Brinckerhoff, Constance E.

2017

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The mitogen-activated protein kinase pathway plays a critical role in regulating immunological properties of BRAF mutant cutaneous melanoma cells

Melanoma research, 2016-06, Vol.26 (3), p.223-235

2016

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What are the therapeutic implications of increased collagen expression in melanoma cells treated with vemurafenib?

Melanoma management, 2016-03, Vol.3 (1), p.5-8

Brinckerhoff, Constance E

2016

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The BRAFV600E inhibitor, PLX4032, increases type I collagen synthesis in melanoma cells

Matrix biology, 2015-10, Vol.48, p.66-77

2015

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The BRAF(V600E) inhibitor, PLX4032, increases type I collagen synthesis in melanoma cells

Matrix biology, 2015-10, Vol.48, p.66-77

2015

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CXCR3 Signaling in BRAF.sup.WT Melanoma Increases IL-8 Expression and Tumorigenicity

PloS one, 2015-03, Vol.10 (3)

2015

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CXCR3 signaling in BRAFWT melanoma increases IL-8 expression and tumorigenicity

PloS one, 2015, Vol.10 (3), p.e0121140

2015

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BRAF inhibition alleviates immune suppression in murine autochthonous melanoma

Cancer immunology research, 2014-11, Vol.2 (11), p.1044-1050

2014

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Multiple murine BRaf(V600E) melanoma cell lines with sensitivity to PLX4032

Pigment cell and melanoma research, 2014-05, Vol.27 (3), p.495

2014

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Multiple murine BRaf V600E melanoma cell lines with sensitivity to PLX4032

Pigment cell and melanoma research, 2014-05, Vol.27 (3), p.495-501

2014

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Multiple murine BRafV600E melanoma cell lines with sensitivity to PLX4032

Pigment cell and melanoma research, 2014-05, Vol.27 (3), p.495-501

2014

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Differential mechanisms of tumor progression in clones from a single heterogeneous human melanoma

Journal of cellular physiology, 2013-04, Vol.228 (4), p.773-780

2013

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Distal Interleukin-1β (IL-1β) Response Element of Human Matrix Metalloproteinase-13 (MMP-13) Binds Activator Protein 1 (AP-1) Transcription Factors and Regulates Gene Expression

The Journal of biological chemistry, 2012-01, Vol.287 (2), p.1189-1197

2012

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A matrix metalloproteinase-1 protease activated receptor-1 signaling axis promotes melanoma invasion and metastasis

Oncogene, 2009-12, Vol.28 (48), p.4237-4248

2009

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Matrix metalloproteinase and G protein coupled receptors: Co-conspirators in the pathogenesis of autoimmune disease and cancer

Journal of autoimmunity, 2009-11, Vol.33 (3), p.214-221

2009

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Site controlled transgenic mice validating increased expression from human matrix metalloproteinase (MMP-1) promoter due to a naturally occurring SNP

Matrix biology, 2009-09, Vol.28 (7), p.425-431

2009

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PTEN suppression of YY1 induces HIF-2 activity in von hippel lindau null renal cell carcinoma

Cancer biology & therapy, 2009-07, Vol.8 (14), p.1389-1401

2009

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CXCR4 and Matrix Metalloproteinase-1 Are Elevated in Breast Carcinoma–Associated Fibroblasts and in Normal Mammary Fibroblasts Exposed to Factors Secreted by Breast Cancer Cells

Molecular cancer research, 2009-07, Vol.7 (7), p.1033-1044

2009

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PTEN suppression of YY1 induces HIF-2α activity in von Hippel Lindau null renal cell carcinoma

Cancer biology & therapy, 2009-07, Vol.8 (14), p.1389-1401

2009

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Wild-type versus mutant MMP-8 in melanoma: 'When you come to a fork in the road, take it'

Pigment cell and melanoma research, 2009-06, Vol.22 (3), p.248-250

2009

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Diesel Exhaust Particles Activate the Matrix-Metalloproteinase-1 Gene in Human Bronchial Epithelia in a β-Arrestin-Dependent Manner via Activation of RAS

Environmental health perspectives, 2009-03, Vol.117 (3), p.400-409

2009

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The 'RASor's' edge: Ras proteins and matrix destruction in arthritis

Arthritis research & therapy, 2009-01, Vol.11 (6), p.136-136

2009

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Identification of a Cigarette Smoke-Responsive Region in the Distal MMP-1 Promoter

American journal of respiratory cell and molecular biology, 2009-01, Vol.40 (1), p.4-12

2009

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Epitope spreading toward wild-type melanocyte-lineage antigens rescues suboptimal immune checkpoint blockade responses

A TLR7 agonist strengthens T and NK cell function during BRAF‐targeted therapy in a preclinical melanoma model

Cancer Stem Cells (CSCs) in melanoma: There's smoke, but is there fire?

The mitogen-activated protein kinase pathway plays a critical role in regulating immunological properties of BRAF mutant cutaneous melanoma cells

What are the therapeutic implications of increased collagen expression in melanoma cells treated with vemurafenib?

The BRAFV600E inhibitor, PLX4032, increases type I collagen synthesis in melanoma cells

The BRAF(V600E) inhibitor, PLX4032, increases type I collagen synthesis in melanoma cells

CXCR3 Signaling in BRAF.sup.WT Melanoma Increases IL-8 Expression and Tumorigenicity

CXCR3 signaling in BRAFWT melanoma increases IL-8 expression and tumorigenicity

BRAF inhibition alleviates immune suppression in murine autochthonous melanoma

Multiple murine BRaf(V600E) melanoma cell lines with sensitivity to PLX4032

Multiple murine BRaf V600E melanoma cell lines with sensitivity to PLX4032

Multiple murine BRafV600E melanoma cell lines with sensitivity to PLX4032

Differential mechanisms of tumor progression in clones from a single heterogeneous human melanoma

Distal Interleukin-1β (IL-1β) Response Element of Human Matrix Metalloproteinase-13 (MMP-13) Binds Activator Protein 1 (AP-1) Transcription Factors and Regulates Gene Expression

A matrix metalloproteinase-1 protease activated receptor-1 signaling axis promotes melanoma invasion and metastasis

Matrix metalloproteinase and G protein coupled receptors: Co-conspirators in the pathogenesis of autoimmune disease and cancer

Site controlled transgenic mice validating increased expression from human matrix metalloproteinase (MMP-1) promoter due to a naturally occurring SNP

PTEN suppression of YY1 induces HIF-2 activity in von hippel lindau null renal cell carcinoma

CXCR4 and Matrix Metalloproteinase-1 Are Elevated in Breast Carcinoma–Associated Fibroblasts and in Normal Mammary Fibroblasts Exposed to Factors Secreted by Breast Cancer Cells

PTEN suppression of YY1 induces HIF-2α activity in von Hippel Lindau null renal cell carcinoma

Wild-type versus mutant MMP-8 in melanoma: 'When you come to a fork in the road, take it'

Diesel Exhaust Particles Activate the Matrix-Metalloproteinase-1 Gene in Human Bronchial Epithelia in a β-Arrestin-Dependent Manner via Activation of RAS

The 'RASor's' edge: Ras proteins and matrix destruction in arthritis

Identification of a Cigarette Smoke-Responsive Region in the Distal MMP-1 Promoter

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