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Pneumococcal Vaccines

Microbiology spectrum, 2019-12, Vol.7 (6)

2019

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Fusion Proteins Containing Family 1 and Family 2 PspA Fragments Elicit Protection against Streptococcus pneumoniae That Correlates with Antibody-Mediated Enhancement of Complement Deposition

Infection and Immunity, 2007-12, Vol.75 (12), p.5930-5938

2007

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Diversity of PspA: Mosaic Genes and Evidence for Past Recombination in Streptococcus pneumoniae

Infection and Immunity, 2000-10, Vol.68 (10), p.5889-5900

2000

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The pspC Gene of Streptococcus pneumoniae Encodes a Polymorphic Protein, PspC, Which Elicits Cross-Reactive Antibodies to PspA and Provides Immunity to Pneumococcal Bacteremia

Infection and Immunity, 1999-12, Vol.67 (12), p.6533-6542

1999

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Prospects for use of interleukin-12 as a mucosal adjuvant for vaccination of humans to protect against respiratory pneumococcal infection

Vaccine, 2008-09, Vol.26 (38), p.4893-4903

2008

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Intranasal Immunization of Mice with a Mixture of the Pneumococcal Proteins PsaA and PspA Is Highly Protective against Nasopharyngeal Carriage of Streptococcus pneumoniae

Infection and Immunity, 2000-02, Vol.68 (2), p.796-800

2000

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Immunization of Mice with Combinations of Pneumococcal Virulence Proteins Elicits Enhanced Protection against Challenge with Streptococcus pneumoniae

Infection and Immunity, 2000-05, Vol.68 (5), p.3028-3033

2000

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Pneumococcal Surface Protein A Inhibits Complement Activation by Streptococcus pneumoniae

Infection and Immunity, 1999-09, Vol.67 (9), p.4720-4724

1999

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Nanogel-based pneumococcal surface protein A nasal vaccine induces microRNA-associated Th17 cell responses with neutralizing antibodies against Streptococcus pneumoniae in macaques

Mucosal immunology, 2015-09, Vol.8 (5), p.1144-1153

2015

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Intranasal Vaccination with Pneumococcal Surface Protein A and Interleukin-12 Augments Antibody-Mediated Opsonization and Protective Immunity against Streptococcus pneumoniae Infection

Infection and Immunity, 2001-11, Vol.69 (11), p.6718-6724

2001

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Competition among Streptococcus pneumoniae for intranasal colonization in a mouse model

Vaccine, 2000-06, Vol.18 (25), p.2895-2901

2000

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Asthma and antibodies to pneumococcal virulence proteins

Infection, 2013-10, Vol.41 (5), p.927-934

2013

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Pneumococcal Surface Protein A Is Expressed In Vivo, and Antibodies to PspA Are Effective for Therapy in a Murine Model of Pneumococcal Sepsis

Infection and Immunity, 2003-12, Vol.71 (12), p.7149-7153

2003

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Pneumococcal surface protein A (PspA) is effective at eliciting T cell‐mediated responses during invasive pneumococcal disease in adults

Clinical and experimental immunology, 2006-08, Vol.145 (2), p.277-286

2006

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Structural properties and evolutionary relationships of PspA, a surface protein of Streptococcus pneumoniae, as revealed by sequence analysis

Journal of Bacteriology, 1992-01, Vol.174 (2), p.601-609

1992

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Characterization of Binding of Human Lactoferrin to Pneumococcal Surface Protein A

Infection and Immunity, 2001-05, Vol.69 (5), p.3372-3381

2001

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Immunization of healthy adults with a single recombinant pneumococcal surface protein A (PspA) variant stimulates broadly cross-reactive antibodies to heterologous PspA molecules

Vaccine, 2000-03, Vol.18 (17), p.1743-1754

2000

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The potential to use PspA and other pneumococcal proteins to elicit protection against pneumococcal infection

Vaccine, 2000-02, Vol.18 (16), p.1707-1711

2000

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Intranasal Immunization of Mice with PspA (Pneumococcal Surface Protein A) Can Prevent Intranasal Carriage, Pulmonary Infection, and Sepsis with Streptococcus pneumoniae

The Journal of infectious diseases, 1997-04, Vol.175 (4), p.839-846

1997

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Role of complement in C-reactive-protein-mediated protection of mice from Streptococcus pneumoniae

Infection and Immunity, 1996-11, Vol.64 (11), p.4850-4853

1996

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Strong association between capsular type and virulence for mice among human isolates of Streptococcus pneumoniae

Infection and Immunity, 1992-01, Vol.60 (1), p.111-116

1992

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Human C-reactive protein is protective against fatal Streptococcus pneumoniae infection in transgenic mice

The Journal of immunology (1950), 1995-09, Vol.155 (5), p.2557-2563

1995

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A pneumolysin-negative mutant of Streptococcus pneumoniae causes chronic bacteremia rather than acute sepsis in mice

Infection and Immunity, 1995-02, Vol.63 (2), p.448-455

1995

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Pneumococcal Diversity: Considerations for New Vaccine Strategies with Emphasis on Pneumococcal Surface Protein A (PspA)

Clinical Microbiology Reviews, 1998-10, Vol.11 (4), p.645-657

1998

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Natural materno‐fetal transfer of antibodies to PspA and to PsaA

Clinical and experimental immunology, 2004-03, Vol.135 (3), p.474-477

2004

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Pneumococcal Vaccines

Fusion Proteins Containing Family 1 and Family 2 PspA Fragments Elicit Protection against Streptococcus pneumoniae That Correlates with Antibody-Mediated Enhancement of Complement Deposition

Diversity of PspA: Mosaic Genes and Evidence for Past Recombination in Streptococcus pneumoniae

The pspC Gene of Streptococcus pneumoniae Encodes a Polymorphic Protein, PspC, Which Elicits Cross-Reactive Antibodies to PspA and Provides Immunity to Pneumococcal Bacteremia

Prospects for use of interleukin-12 as a mucosal adjuvant for vaccination of humans to protect against respiratory pneumococcal infection

Intranasal Immunization of Mice with a Mixture of the Pneumococcal Proteins PsaA and PspA Is Highly Protective against Nasopharyngeal Carriage of Streptococcus pneumoniae

Immunization of Mice with Combinations of Pneumococcal Virulence Proteins Elicits Enhanced Protection against Challenge with Streptococcus pneumoniae

Pneumococcal Surface Protein A Inhibits Complement Activation by Streptococcus pneumoniae

Nanogel-based pneumococcal surface protein A nasal vaccine induces microRNA-associated Th17 cell responses with neutralizing antibodies against Streptococcus pneumoniae in macaques

Intranasal Vaccination with Pneumococcal Surface Protein A and Interleukin-12 Augments Antibody-Mediated Opsonization and Protective Immunity against Streptococcus pneumoniae Infection

Competition among Streptococcus pneumoniae for intranasal colonization in a mouse model

Asthma and antibodies to pneumococcal virulence proteins

Pneumococcal Surface Protein A Is Expressed In Vivo, and Antibodies to PspA Are Effective for Therapy in a Murine Model of Pneumococcal Sepsis

Pneumococcal surface protein A (PspA) is effective at eliciting T cell‐mediated responses during invasive pneumococcal disease in adults

Structural properties and evolutionary relationships of PspA, a surface protein of Streptococcus pneumoniae, as revealed by sequence analysis

Characterization of Binding of Human Lactoferrin to Pneumococcal Surface Protein A

Immunization of healthy adults with a single recombinant pneumococcal surface protein A (PspA) variant stimulates broadly cross-reactive antibodies to heterologous PspA molecules

The potential to use PspA and other pneumococcal proteins to elicit protection against pneumococcal infection

Intranasal Immunization of Mice with PspA (Pneumococcal Surface Protein A) Can Prevent Intranasal Carriage, Pulmonary Infection, and Sepsis with Streptococcus pneumoniae

Role of complement in C-reactive-protein-mediated protection of mice from Streptococcus pneumoniae

Strong association between capsular type and virulence for mice among human isolates of Streptococcus pneumoniae

Human C-reactive protein is protective against fatal Streptococcus pneumoniae infection in transgenic mice

A pneumolysin-negative mutant of Streptococcus pneumoniae causes chronic bacteremia rather than acute sepsis in mice

Pneumococcal Diversity: Considerations for New Vaccine Strategies with Emphasis on Pneumococcal Surface Protein A (PspA)

Natural materno‐fetal transfer of antibodies to PspA and to PsaA

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