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Distinctive microRNA signature of acute myeloid leukemia bearing cytoplasmic mutated nucleophosmin

Proceedings of the National Academy of Sciences - PNAS, 2008-03, Vol.105 (10), p.3945-3950

2008

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Pharmacologic inhibition of CDK4/6: mechanistic evidence for selective activity or acquired resistance in acute myeloid leukemia

Blood, 2007-09, Vol.110 (6), p.2075-2083

2007

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Novel c-CBL and CBL-b ubiquitin ligase mutations in human acute myeloid leukemia

Blood, 2007-08, Vol.110 (3), p.1022-1024

2007

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Discovery of a Fusion Kinase in EOL-1 Cells and Idiopathic Hypereosinophilic Syndrome

Proceedings of the National Academy of Sciences - PNAS, 2003-06, Vol.100 (13), p.7830-7835

2003

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Inhibition of Ras–effector interactions by cyclic peptides

MedChemComm, 2013, Vol.4 (2), p.378-382

2013

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Inhibition of Ras Signaling by Blocking Ras-Effector Interactions with Cyclic Peptides

Angewandte Chemie (International ed.), 2015-06, Vol.54 (26), p.7602-7606

International ed. in English, 2015

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Fathoming Flt3

Blood, 2009-04, Vol.113 (17), p.3889-3890

Briesewitz, Roger

2009

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Efficient Delivery of Cyclic Peptides into Mammalian Cells with Short Sequence Motifs

ACS chemical biology, 2013-02, Vol.8 (2), p.423-431

2013

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RET Fusion Genes in Non―Small-Cell Lung Cancer

Journal of clinical oncology, 2012-12, Vol.30 (35), p.4439-4441

2012

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Affinity Modulation of Small-Molecule Ligands by Borrowing Endogenous Protein Surfaces

Proceedings of the National Academy of Sciences - PNAS, 1999-03, Vol.96 (5), p.1953-1958

1999

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Creating Diverse Target-Binding Surfaces on FKBP12: Synthesis and Evaluation of a Rapamycin Analogue Library

ACS combinatorial science, 2011-09, Vol.13 (5), p.486-495

2011

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Pharmacologic activation of the tumor suppressor PP2A as a potential therapy for treating Jak2 V617F‐driven myeloproliferative disorders

The FASEB journal, 2009-04, Vol.23 (S1)

2009

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Stem cell factor and interleukin-2/15 combine to enhance MAPK-mediated proliferation of human natural killer cells

Blood, 2009-03, Vol.113 (12), p.2706-2714

2009

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Activating PP2A Tumor Suppressor Activity as a Potential Therapy for Treating Jak2 V617F-Driven Myeloproliferative Disorders

Blood, 2007-11, Vol.110 (11), p.3548-3548

2007

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Inhibition of Ras-Effector Interaction by Cyclic Peptides

MedChemComm, 2013-02, Vol.4 (2), p.378-382

2013

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Inhibition of Ras-effector interactions by cyclic peptidesElectronic supplementary information (ESI) available: Details of library synthesis and screening and biochemical assays. See DOI: 10.1039/c2md20329d

2013-01

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Inhibition of Ras Signaling by Blocking Ras-Effector Interactions with Cyclic Peptides

Angewandte Chemie, 2015-06, Vol.127 (26), p.7712-7716

2015

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A Bifunctional Molecule That Displays Context-Dependent Cellular Activity

Journal of the American Chemical Society, 2003-06, Vol.125 (25), p.7575-7580

2003

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Distinctive microRNA signature of acute myeloid leukemia bearing cytoplasmic mutated nucleophosmin

Antagonistic activities of the immunomodulator and PP2A-activating drug FTY720 (Fingolimod, Gilenya) in Jak2-driven hematologic malignancies

Pharmacologic inhibition of CDK4/6: mechanistic evidence for selective activity or acquired resistance in acute myeloid leukemia

Novel c-CBL and CBL-b ubiquitin ligase mutations in human acute myeloid leukemia

Discovery of a Fusion Kinase in EOL-1 Cells and Idiopathic Hypereosinophilic Syndrome

Inhibition of Ras–effector interactions by cyclic peptides

Inhibition of Ras Signaling by Blocking Ras-Effector Interactions with Cyclic Peptides

Fathoming Flt3

Efficient Delivery of Cyclic Peptides into Mammalian Cells with Short Sequence Motifs

RET Fusion Genes in Non―Small-Cell Lung Cancer

Sp1/NFκB/HDAC/ miR-29b Regulatory Network in KIT-Driven Myeloid Leukemia

Affinity Modulation of Small-Molecule Ligands by Borrowing Endogenous Protein Surfaces

Creating Diverse Target-Binding Surfaces on FKBP12: Synthesis and Evaluation of a Rapamycin Analogue Library

Pharmacologic activation of the tumor suppressor PP2A as a potential therapy for treating Jak2 V617F‐driven myeloproliferative disorders

Stem cell factor and interleukin-2/15 combine to enhance MAPK-mediated proliferation of human natural killer cells

Activating PP2A Tumor Suppressor Activity as a Potential Therapy for Treating Jak2 V617F-Driven Myeloproliferative Disorders

Inhibition of Ras-Effector Interaction by Cyclic Peptides

Inhibition of Ras-effector interactions by cyclic peptidesElectronic supplementary information (ESI) available: Details of library synthesis and screening and biochemical assays. See DOI: 10.1039/c2md20329d

Pharmacologic Restoration of PP2A Activity and Interference with the SET-PP2A Interplay by FTY720 and Its Non-Immunosuppressive Derivative as a Novel and Efficient Therapy for Ph-Negative Myeloproliferative Disorders

Inhibition of Ras Signaling by Blocking Ras-Effector Interactions with Cyclic Peptides

A Bifunctional Molecule That Displays Context-Dependent Cellular Activity

The Mll PTD and Flt3 ITD Double Knock-In Mouse Develops Acute Leukemia and Recapitulates Phenotypic, Molecular and Epigenetic Characteristics of the Counterpart Human Acute Myeloid Leukemia

FTY720 but Not Its Immunosuppressive Phosphorylated Form FTY720-P Exerts Anti-Leukemic Activity towards Ph(+) and Ph(−) Myeloproliferative Disorders through Reactivation of the PP2A Tumor Suppressor

Sp1/NFI[ordmB/HDAC/miR-29b Regulatory Network in KIT-Driven Myeloid Leukemia

Evidence of MicroRNA-29b and Sp1/NFκB-HDAC Regulatory Network for KIT Expression in KIT-Driven Acute Myeloid Leukemia (AML): Biologic and Therapeutic Implications

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