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Phase III Prospective Randomized Double-Blind Placebo-Controlled Trial of Plerixafor Plus Granulocyte Colony-Stimulating Factor Compared With Placebo Plus Granulocyte Colony-Stimulating Factor for Autologous Stem-Cell Mobilization and Transplantation for Patients With Non-Hodgkin's Lymphoma

Journal of clinical oncology, 2009-10, Vol.27 (28), p.4767-4773

2009

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Mobilization of hematopoietic progenitor cells in healthy volunteers by AMD3100, a CXCR4 antagonist

Blood, 2003-10, Vol.102 (8), p.2728-2730

2003

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Chemosensitization of acute myeloid leukemia (AML) following mobilization by the CXCR4 antagonist AMD3100

Blood, 2009-06, Vol.113 (24), p.6206-6214

2009

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Rapid mobilization of functional donor hematopoietic cells without G-CSF using AMD3100, an antagonist of the CXCR4/SDF-1 interaction

Blood, 2008-08, Vol.112 (4), p.990-998

2008

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Safety, pharmacokinetics, and antiviral activity of AMD3100, a selective CXCR4 receptor inhibitor, in HIV-1 infection

Journal of acquired immune deficiency syndromes (1999), 2004-10, Vol.37 (2), p.1253

2004

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Chemokine receptor inhibition by AMD3100 is strictly confined to CXCR4

FEBS letters, 2002-09, Vol.527 (1-3), p.255-262

2002

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Molecular Mechanism of Action of Monocyclam Versus Bicyclam Non-peptide Antagonists in the CXCR4 Chemokine Receptor

The Journal of biological chemistry, 2007-09, Vol.282 (37), p.27354-27365

2007

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Comparison of the Potential Multiple Binding Modes of Bicyclam, Monocylam, and Noncyclam Small-Molecule CXC Chemokine Receptor 4 Inhibitors

Molecular pharmacology, 2008-12, Vol.74 (6), p.1485-1495

2008

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Discovery of Novel Small Molecule Orally Bioavailable C−X−C Chemokine Receptor 4 Antagonists That Are Potent Inhibitors of T-Tropic (X4) HIV-1 Replication

Journal of medicinal chemistry, 2010-04, Vol.53 (8), p.3376-3388

2010

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AMD3100, a CxCR4 Antagonist, Attenuates Allergic Lung Inflammation and Airway Hyperreactivity

The American journal of pathology, 2002-04, Vol.160 (4), p.1353-1360

2002

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Molecular mechanism of AMD3100 antagonism in the CXCR4 receptor: transfer of binding site to the CXCR3 receptor

The Journal of biological chemistry, 2004-01, Vol.279 (4), p.3033-3041

2004

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The molecular pharmacology of AMD11070: An orally bioavailable CXCR4 HIV entry inhibitor

Biochemical pharmacology, 2012-02, Vol.83 (4), p.472-479

2012

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Structural analogues of AMD3100 mobilise haematopoietic progenitor cells from bone marrow in vivo according to their ability to inhibit CXCL12 binding to CXCR4 in vitro

British journal of haematology, 2006-08, Vol.134 (3), p.326-329

2006

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AMD3465, a monomacrocyclic CXCR4 antagonist and potent HIV entry inhibitor

Biochemical pharmacology, 2005-09, Vol.70 (5), p.752-761

2005

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Pharmacokinetics and Safety of AMD-3100, a Novel Antagonist of the CXCR-4 Chemokine Receptor, in Human Volunteers

Antimicrobial Agents and Chemotherapy, 2000-06, Vol.44 (6), p.1667-1673

2000

Volltextzugriff (PDF)

Synthesis and Structure−Activity Relationships of Azamacrocyclic C-X-C Chemokine Receptor 4 Antagonists: Analogues Containing a Single Azamacrocyclic Ring are Potent Inhibitors of T-Cell Tropic (X4) HIV-1 Replication

Journal of medicinal chemistry, 2010-02, Vol.53 (3), p.1250-1260

2010

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Pharmacology of AMD3465: A small molecule antagonist of the chemokine receptor CXCR4

Biochemical pharmacology, 2009-10, Vol.78 (8), p.993-1000

2009

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Mobilization as a preparative regimen for hematopoietic stem cell transplantation

Blood, 2006-05, Vol.107 (9), p.3764-3771

2006

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Spontaneous Enzymatically Mediated Dynamic Kinetic Resolution of 8-Amino-5,6,7,8-tetrahydroquinoline

Journal of organic chemistry, 2007-01, Vol.72 (2), p.669-671

2007

Volltextzugriff (PDF)

HIV - 1 entry inhibition by small - molecule CCR5 antagonists: A combined molecular modeling and mutant study using a high - throughput assay

Virology (New York, N.Y.), 2011-05, Vol.413 (2), p.231-243

2011

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Prospective CCR5 Small Molecule Antagonist Compound Design Using a Combined Mutagenesis/Modeling Approach

Journal of the American Chemical Society, 2011-10, Vol.133 (41), p.16477-16485

2011

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Molecular Interactions of Cyclam and Bicyclam Non-peptide Antagonists with the CXCR4 Chemokine Receptor

The Journal of biological chemistry, 2001-04, Vol.276 (17), p.14153-14160

2001

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Inhibition of Human Immunodeficiency Virus Replication by a Dual CCR5/CXCR4 Antagonist

Journal of Virology, 2004-12, Vol.78 (23), p.12996-13006

2004

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Practical Convergent Laboratory-Scale Synthesis of a CCR5 Receptor Antagonist

Organic process research & development, 2012-01, Vol.16 (1), p.109-116

2012

Volltextzugriff (PDF)

Enzymatic Resolution of Bicyclic 1-Heteroarylamines Using Candida antarctica Lipase B

Journal of organic chemistry, 2003-05, Vol.68 (9), p.3546-3551

2003

Volltextzugriff (PDF)

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Phase III Prospective Randomized Double-Blind Placebo-Controlled Trial of Plerixafor Plus Granulocyte Colony-Stimulating Factor Compared With Placebo Plus Granulocyte Colony-Stimulating Factor for Autologous Stem-Cell Mobilization and Transplantation for Patients With Non-Hodgkin's Lymphoma

Mobilization of hematopoietic progenitor cells in healthy volunteers by AMD3100, a CXCR4 antagonist

Chemosensitization of acute myeloid leukemia (AML) following mobilization by the CXCR4 antagonist AMD3100

Rapid mobilization of functional donor hematopoietic cells without G-CSF using AMD3100, an antagonist of the CXCR4/SDF-1 interaction

Safety, pharmacokinetics, and antiviral activity of AMD3100, a selective CXCR4 receptor inhibitor, in HIV-1 infection

Chemokine receptor inhibition by AMD3100 is strictly confined to CXCR4

Molecular Mechanism of Action of Monocyclam Versus Bicyclam Non-peptide Antagonists in the CXCR4 Chemokine Receptor

Comparison of the Potential Multiple Binding Modes of Bicyclam, Monocylam, and Noncyclam Small-Molecule CXC Chemokine Receptor 4 Inhibitors

Discovery of Novel Small Molecule Orally Bioavailable C−X−C Chemokine Receptor 4 Antagonists That Are Potent Inhibitors of T-Tropic (X4) HIV-1 Replication

AMD3100, a CxCR4 Antagonist, Attenuates Allergic Lung Inflammation and Airway Hyperreactivity

Molecular mechanism of AMD3100 antagonism in the CXCR4 receptor: transfer of binding site to the CXCR3 receptor

The molecular pharmacology of AMD11070: An orally bioavailable CXCR4 HIV entry inhibitor

Structural analogues of AMD3100 mobilise haematopoietic progenitor cells from bone marrow in vivo according to their ability to inhibit CXCL12 binding to CXCR4 in vitro

AMD3465, a monomacrocyclic CXCR4 antagonist and potent HIV entry inhibitor

Pharmacokinetics and Safety of AMD-3100, a Novel Antagonist of the CXCR-4 Chemokine Receptor, in Human Volunteers

Synthesis and Structure−Activity Relationships of Azamacrocyclic C-X-C Chemokine Receptor 4 Antagonists: Analogues Containing a Single Azamacrocyclic Ring are Potent Inhibitors of T-Cell Tropic (X4) HIV-1 Replication

Pharmacology of AMD3465: A small molecule antagonist of the chemokine receptor CXCR4

Mobilization as a preparative regimen for hematopoietic stem cell transplantation

Spontaneous Enzymatically Mediated Dynamic Kinetic Resolution of 8-Amino-5,6,7,8-tetrahydroquinoline

HIV - 1 entry inhibition by small - molecule CCR5 antagonists: A combined molecular modeling and mutant study using a high - throughput assay

Prospective CCR5 Small Molecule Antagonist Compound Design Using a Combined Mutagenesis/Modeling Approach

Molecular Interactions of Cyclam and Bicyclam Non-peptide Antagonists with the CXCR4 Chemokine Receptor

Inhibition of Human Immunodeficiency Virus Replication by a Dual CCR5/CXCR4 Antagonist

Practical Convergent Laboratory-Scale Synthesis of a CCR5 Receptor Antagonist

Enzymatic Resolution of Bicyclic 1-Heteroarylamines Using Candida antarctica Lipase B

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