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The Problem of Host and Pathogen Genetic Variability for Developing Strategies of Universally Efficacious Vaccination against and Personalised Immunotherapy of Tuberculosis: Potential Solutions?

International journal of molecular sciences, 2023-01, Vol.24 (3), p.1887

Bretscher, Peter A

2023

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A Plausible Framework Reveals Potential Similarities in the Regulation of Immunity against Some Cancers and Some Infectious Agents: Implications for Prevention and Treatment

Cancers, 2024-04, Vol.16 (7), p.1431

Bretscher, Peter A

2024

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Facing the Increased Prevalence of Antibiotic-Resistant M. tuberculosis : Exploring the Feasibility of Realising Koch's Aspiration of Immunotherapy of Tuberculosis

Antibiotics (Basel), 2022-03, Vol.11 (3), p.371

Bretscher, Peter A

2022

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On antigen‐specific signals, immune class regulation and energetics: Report III from the workshops on foundational concepts of immune regulation

Scandinavian journal of immunology, 2023-09, Vol.98 (3), p.e13311-n/a

2023

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A Two-Step, Two-Signal Model for the Primary Activation of Precursor Helper T Cells

Proceedings of the National Academy of Sciences - PNAS, 1999-01, Vol.96 (1), p.185-190

Bretscher, Peter A.

1999

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The role of cytokines in determining the Th1/Th2 phenotype of an immune response: Coherence of the T cell response and the Cytokine Implementation Hypothesis

Scandinavian journal of immunology, 2022-01, Vol.95 (1), p.n/a

Bretscher, Peter A.

2022

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An integrated view of immunological tolerance

Scandinavian journal of immunology, 2022-09, Vol.96 (3), p.n/a

Bretscher, Peter A.

2022

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The historical postulate: Is it the basis, at the level of the system, for self‐nonself discrimination?

Scandinavian journal of immunology, 2021-08, Vol.94 (2), p.e13033-n/a

Bretscher, Peter A.

2021

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The history of the two‐signal model of lymphocyte activation: A personal perspective

Scandinavian journal of immunology, 2019-06, Vol.89 (6), p.e12762-n/a

Bretscher, Peter A.

2019

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Antigen presenting B cells facilitate CD4 T cell cooperation resulting in enhanced generation of effector and memory CD4 T cells

PloS one, 2013-10, Vol.8 (10), p.e77346-e77346

2013

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Does T Cell Activation Require a Quorum of Lymphocytes?

The Journal of immunology (1950), 2018-11, Vol.201 (10), p.2855-2861

2018

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Is the Framework of Cohn's ‘Tritope Model’ for How T Cell Receptors Recognize Peptide/Self‐MHC Complexes and Allo‐MHC Plausible?

Scandinavian journal of immunology, 2016-05, Vol.83 (5), p.311-313

Bretscher, Peter A.

2016

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Direct demonstration of CD4 T cell cooperation in the primary in vivo generation of CD4 effector T cells

International immunology, 2012-08, Vol.24 (8), p.519-527

2012

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Can interruption/withdrawl of anti‐retroviral therapy provide personalized immunotherapy against HIV‐1?

Scandinavian journal of immunology, 2020-12, Vol.92 (6), p.e12934-n/a

2020

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CD4 T cell cooperation is required for the in vivo activation of CD4 T cells

International immunology, 2009-11, Vol.21 (11), p.1213-1224

2009

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On T cell development, T cell signals, T cell specificity and sensitivity, and the autoimmunity facilitated by lymphopenia

Scandinavian journal of immunology, 2020-06, Vol.91 (6), p.e12888-n/a

2020

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On how the immune system preferentially interacts with antigen‐specific molecules bound to antigen over unbound molecules, with emphasis on B cell receptor signalling

Scandinavian journal of immunology, 2019-09, Vol.90 (3), p.e12795-n/a

2019

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The number of responding CD4 T cells and the dose of antigen conjointly determine the TH1/TH2 phenotype by modulating B7/CD28 interactions

The Journal of immunology (1950), 2014-06, Vol.192 (11), p.5140-5150

2014

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Activation of thymic T cells by MHC alloantigen requires syngeneic, activated CD4+ T cells and B cells as APC

International immunology, 2006-05, Vol.18 (5), p.719-728

2006

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Analysis of cytokine‐producing Th cells from hen egg lysozyme‐immunized mice reveals large numbers specific for “cryptic” peptides and different repertoires among different Th populations

European journal of immunology, 2005-01, Vol.35 (1), p.56-65

2005

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A Strategy for Prophylactic Vaccination Against HIV

Science (American Association for the Advancement of Science), 1993-05, Vol.260 (5112), p.1270-1272

1993

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Different immune correlates associated with tumor progression and regression: implications for prevention and treatment of cancer

Cancer Immunology, Immunotherapy, 2008-08, Vol.57 (8), p.1125-1136

2008

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Distinct Immunity in Patients with Visceral Leishmaniasis from that in Subclinically Infected and Drug-Cured People: Implications for the Mechanism Underlying Drug Cure

The Journal of infectious diseases, 2001-07, Vol.184 (1), p.112-115

2001

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Mycobacterial Dose Defines the Th1/Th2 Nature of the Immune Response Independently of Whether Immunization Is Administered by the Intravenous, Subcutaneous, or Intradermal Route

Infection and Immunity, 1998-12, Vol.66 (12), p.5743-5750

1998

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The activation, by antigen, of naïve TCR transgenic CD4 T cells cultured at physiological, rather than artificially high, frequencies more accurately reflects the in vivo activation of normal numbers of naïve CD4+ T cells

Cellular immunology, 2012, Vol.274 (1-2), p.115-120

2012

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The Problem of Host and Pathogen Genetic Variability for Developing Strategies of Universally Efficacious Vaccination against and Personalised Immunotherapy of Tuberculosis: Potential Solutions?

A Plausible Framework Reveals Potential Similarities in the Regulation of Immunity against Some Cancers and Some Infectious Agents: Implications for Prevention and Treatment

Facing the Increased Prevalence of Antibiotic-Resistant M. tuberculosis : Exploring the Feasibility of Realising Koch's Aspiration of Immunotherapy of Tuberculosis

On antigen‐specific signals, immune class regulation and energetics: Report III from the workshops on foundational concepts of immune regulation

A Two-Step, Two-Signal Model for the Primary Activation of Precursor Helper T Cells

The role of cytokines in determining the Th1/Th2 phenotype of an immune response: Coherence of the T cell response and the Cytokine Implementation Hypothesis

An integrated view of immunological tolerance

The historical postulate: Is it the basis, at the level of the system, for self‐nonself discrimination?

The history of the two‐signal model of lymphocyte activation: A personal perspective

Antigen presenting B cells facilitate CD4 T cell cooperation resulting in enhanced generation of effector and memory CD4 T cells

Does T Cell Activation Require a Quorum of Lymphocytes?

Is the Framework of Cohn's ‘Tritope Model’ for How T Cell Receptors Recognize Peptide/Self‐MHC Complexes and Allo‐MHC Plausible?

Direct demonstration of CD4 T cell cooperation in the primary in vivo generation of CD4 effector T cells

Can interruption/withdrawl of anti‐retroviral therapy provide personalized immunotherapy against HIV‐1?

CD4 T cell cooperation is required for the in vivo activation of CD4 T cells

On T cell development, T cell signals, T cell specificity and sensitivity, and the autoimmunity facilitated by lymphopenia

On how the immune system preferentially interacts with antigen‐specific molecules bound to antigen over unbound molecules, with emphasis on B cell receptor signalling

The number of responding CD4 T cells and the dose of antigen conjointly determine the TH1/TH2 phenotype by modulating B7/CD28 interactions

Activation of thymic T cells by MHC alloantigen requires syngeneic, activated CD4+ T cells and B cells as APC

Analysis of cytokine‐producing Th cells from hen egg lysozyme‐immunized mice reveals large numbers specific for “cryptic” peptides and different repertoires among different Th populations

A Strategy for Prophylactic Vaccination Against HIV

Different immune correlates associated with tumor progression and regression: implications for prevention and treatment of cancer

Distinct Immunity in Patients with Visceral Leishmaniasis from that in Subclinically Infected and Drug-Cured People: Implications for the Mechanism Underlying Drug Cure

Mycobacterial Dose Defines the Th1/Th2 Nature of the Immune Response Independently of Whether Immunization Is Administered by the Intravenous, Subcutaneous, or Intradermal Route

The activation, by antigen, of naïve TCR transgenic CD4 T cells cultured at physiological, rather than artificially high, frequencies more accurately reflects the in vivo activation of normal numbers of naïve CD4+ T cells

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