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Metabolomic signature of brain cancer

Molecular carcinogenesis, 2017-11, Vol.56 (11), p.2355-2371

2017

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Phase 2 trial of hypoxia activated evofosfamide (TH302) for treatment of recurrent bevacizumab-refractory glioblastoma

Scientific reports, 2021-01, Vol.11 (1), p.2306-2306, Article 2306

2021

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Hypoxia in astrocytic tumors and implications for therapy

Neurobiology of disease, 2016-01, Vol.85, p.227-233

2016

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Lysine-specific histone demethylase 1A (KDM1A/LSD1) inhibition attenuates DNA double-strand break repair and augments the efficacy of temozolomide in glioblastoma

Neuro-oncology (Charlottesville, Va.), 2023-07, Vol.25 (7), p.1249-1261

2023

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Sacituzumab Govitecan in patients with breast cancer brain metastases and recurrent glioblastoma: a phase 0 window-of-opportunity trial

Nature communications, 2024-08, Vol.15 (1), p.6707-11, Article 6707

2024

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KDM1A inhibition is effective in reducing stemness and treating triple negative breast cancer

Breast cancer research and treatment, 2021-01, Vol.185 (2), p.343-357

2021

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NSAID Use Reduces Breast Cancer Recurrence in Overweight and Obese Women: Role of Prostaglandin-Aromatase Interactions

Cancer research (Chicago, Ill.), 2014-08, Vol.74 (16), p.4446-4457

2014

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Assessment of tumor hypoxia and perfusion in recurrent glioblastoma following bevacizumab failure using MRI and 18F-FMISO PET

Scientific reports, 2021-04, Vol.11 (1), p.7632-7632, Article 7632

2021

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Circulating metabolites associated with tumor hypoxia and early response to treatment in bevacizumab-refractory glioblastoma after combined bevacizumab and evofosfamide

Frontiers in oncology, 2022-09, Vol.12, p.900082-900082

2022

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Obesity-associated systemic interleukin-6 promotes pre-adipocyte aromatase expression via increased breast cancer cell prostaglandin E2 production

Breast cancer research and treatment, 2015-01, Vol.149 (1), p.49-57

2015

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Phase I study of MRX34, a liposomal miR-34a mimic, administered twice weekly in patients with advanced solid tumors

Investigational new drugs, 2017-04, Vol.35 (2), p.180-188

2017

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Global DNA methylation profiling reveals chromosomal instability in IDH-mutant astrocytomas

Acta neuropathologica communications, 2022-03, Vol.10 (1), p.32-32, Article 32

2022

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Obesity Suppresses Estrogen Receptor Beta Expression in Breast Cancer Cells via a HER2-Mediated Pathway

PloS one, 2015-12, Vol.10 (12), p.e0145452-e0145452

2015

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The enhancing effects of obesity on mammary tumor growth and Akt/mTOR pathway activation persist after weight loss and are reversed by RAD001

Molecular carcinogenesis, 2013-06, Vol.52 (6), p.446-458

2013

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Phase 1 study of MRX34, a liposomal miR-34a mimic, in patients with advanced solid tumours

British journal of cancer, 2020-05, Vol.122 (11), p.1630-1637

2020

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ANG1005, a Brain-Penetrating Peptide-Drug Conjugate, Shows Activity in Patients with Breast Cancer with Leptomeningeal Carcinomatosis and Recurrent Brain Metastases

Clinical cancer research, 2020-06, Vol.26 (12), p.2789-2799

2020

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The oncogenic RNA-binding protein Musashi1 is regulated by tumor suppressor miRNAs

RNA biology, 2011-09, Vol.8 (5), p.817-828

2011

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KDM1 is a novel therapeutic target for the treatment of gliomas

Oncotarget, 2013-01, Vol.4 (1), p.18-28

2013

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Stable Isotope Dilution LC-HRMS Assay To Determine Free SN-38, Total SN-38, and SN-38G in a Tumor Xenograft Model after Intravenous Administration of Antibody–Drug Conjugate (Sacituzumab Govitecan)

Analytical chemistry (Washington), 2020-01, Vol.92 (1), p.1260-1267

2020

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Flotillin-1 palmitoylation is essential for its stability and subsequent tumor promoting capabilities

Oncogene, 2024-03, Vol.43 (14), p.1063-1074

2024

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Safety and Efficacy of Tucatinib, Letrozole, and Palbociclib in Patients with Previously Treated HR+/HER2+ Breast Cancer

Clinical cancer research, 2023-12, Vol.29 (24), p.5021-5030

2023

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Protein imprinting in polyacrylamide-based gels

Biomaterials, 2014-10, Vol.35 (30), p.8659-8668

2014

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Everolimus Inhibits the Progression of Ductal Carcinoma In Situ to Invasive Breast Cancer Via Downregulation of MMP9 Expression

Clinical cancer research, 2020-03, Vol.26 (6), p.1486-1496

2020

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Preclinical Development of Brain Permeable ERβ Agonist for the Treatment of Glioblastoma

Molecular cancer therapeutics, 2023-11, Vol.22 (11), p.1248-1260

2023

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FASN inhibition as a potential treatment for endocrine-resistant breast cancer

Breast cancer research and treatment, 2021-06, Vol.187 (2), p.375-386

2021

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Metabolomic signature of brain cancer

Phase 2 trial of hypoxia activated evofosfamide (TH302) for treatment of recurrent bevacizumab-refractory glioblastoma

Hypoxia in astrocytic tumors and implications for therapy

Lysine-specific histone demethylase 1A (KDM1A/LSD1) inhibition attenuates DNA double-strand break repair and augments the efficacy of temozolomide in glioblastoma

Sacituzumab Govitecan in patients with breast cancer brain metastases and recurrent glioblastoma: a phase 0 window-of-opportunity trial

KDM1A inhibition is effective in reducing stemness and treating triple negative breast cancer

NSAID Use Reduces Breast Cancer Recurrence in Overweight and Obese Women: Role of Prostaglandin-Aromatase Interactions

Assessment of tumor hypoxia and perfusion in recurrent glioblastoma following bevacizumab failure using MRI and 18F-FMISO PET

Circulating metabolites associated with tumor hypoxia and early response to treatment in bevacizumab-refractory glioblastoma after combined bevacizumab and evofosfamide

Obesity-associated systemic interleukin-6 promotes pre-adipocyte aromatase expression via increased breast cancer cell prostaglandin E2 production

Phase I study of MRX34, a liposomal miR-34a mimic, administered twice weekly in patients with advanced solid tumors

Global DNA methylation profiling reveals chromosomal instability in IDH-mutant astrocytomas

Obesity Suppresses Estrogen Receptor Beta Expression in Breast Cancer Cells via a HER2-Mediated Pathway

The enhancing effects of obesity on mammary tumor growth and Akt/mTOR pathway activation persist after weight loss and are reversed by RAD001

Phase 1 study of MRX34, a liposomal miR-34a mimic, in patients with advanced solid tumours

ANG1005, a Brain-Penetrating Peptide-Drug Conjugate, Shows Activity in Patients with Breast Cancer with Leptomeningeal Carcinomatosis and Recurrent Brain Metastases

The oncogenic RNA-binding protein Musashi1 is regulated by tumor suppressor miRNAs

KDM1 is a novel therapeutic target for the treatment of gliomas

Stable Isotope Dilution LC-HRMS Assay To Determine Free SN-38, Total SN-38, and SN-38G in a Tumor Xenograft Model after Intravenous Administration of Antibody–Drug Conjugate (Sacituzumab Govitecan)

Flotillin-1 palmitoylation is essential for its stability and subsequent tumor promoting capabilities

Safety and Efficacy of Tucatinib, Letrozole, and Palbociclib in Patients with Previously Treated HR+/HER2+ Breast Cancer

Protein imprinting in polyacrylamide-based gels

Everolimus Inhibits the Progression of Ductal Carcinoma In Situ to Invasive Breast Cancer Via Downregulation of MMP9 Expression

Preclinical Development of Brain Permeable ERβ Agonist for the Treatment of Glioblastoma

FASN inhibition as a potential treatment for endocrine-resistant breast cancer

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