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Circulating mitochondria in organ donors promote allograft rejection

American journal of transplantation, 2019-07, Vol.19 (7), p.1917-1929

2019

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Higher thresholds for the utilization of steatotic allografts in liver transplantation: Analysis from a U.S. national database

PloS one, 2020-04, Vol.15 (4), p.e0230995-e0230995

2020

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Effects of Immunosuppressive Medications on Mitochondrial Function

The Journal of surgical research, 2020-05, Vol.249, p.50-57

2020

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Immunomodulatory Activities of the Heparan Sulfate Mimetic PG545

Heparanase, 2020, p.461-470

2020

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PD-L1 serves as a double agent in separating GVL from GVHD

The Journal of clinical investigation, 2017-05, Vol.127 (5), p.1627-1630

2017

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GCNT1-Mediated O -Glycosylation of the Sialomucin CD43 Is a Sensitive Indicator of Notch Signaling in Activated T Cells

The Journal of immunology (1950), 2020-03, Vol.204 (6), p.1674-1688

2020

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A Phase I study of the novel immunomodulatory agent PG545 (pixatimod) in subjects with advanced solid tumours

British journal of cancer, 2018-04, Vol.118 (8), p.1035-1041

2018

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Heparan sulfate is a plasma biomarker of acute cellular allograft rejection

PloS one, 2018-08, Vol.13 (8), p.e0200877-e0200877

2018

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Graft-derived extracellular vesicles transported across subcapsular sinus macrophages elicit B cell alloimmunity after transplantation

Science translational medicine, 2021-03, Vol.13 (585)

2021

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Challenges, highlights, and opportunities in cellular transplantation: A white paper of the current landscape

American journal of transplantation, 2021-10, Vol.21 (10), p.3225-3238

2021

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Heparan sulfate mimetic PG545-mediated antilymphoma effects require TLR9-dependent NK cell activation

The Journal of clinical investigation, 2016-01, Vol.126 (1), p.207-219

2016

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Modification of host dendritic cells by microchimerism-derived extracellular vesicles generates split tolerance

Proceedings of the National Academy of Sciences - PNAS, 2017-01, Vol.114 (5), p.1099-1104

2017

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Heparan sulfate, an endogenous TLR4 agonist, promotes acute GVHD after allogeneic stem cell transplantation

Blood, 2012-10, Vol.120 (14), p.2899-2908

2012

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Extracellular Mitochondrial DNA and N-Formyl Peptides in Trauma and Critical Illness: A Systematic Review

Critical care medicine, 2018-12, Vol.46 (12), p.2018-2028

2018

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Early Notch Signals Induce a Pathogenic Molecular Signature during Priming of Alloantigen-Specific Conventional CD4 + T Cells in Graft-versus-Host Disease

The Journal of immunology (1950), 2019-07, Vol.203 (2), p.557-568

2019

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Dendritic Cell Therapy in Transplantation, Phenotype Governs Destination and Function

Transplantation, 2018-10, Vol.102 (10), p.1593-1594

2018

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Targeting Glycolysis in Alloreactive T Cells to Prevent Acute Graft- Versus -Host Disease While Preserving Graft-Versus-Leukemia Effect

Frontiers in immunology, 2022-02, Vol.13, p.751296-751296

2022

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Immunomodulatory activities of pixatimod: emerging nonclinical and clinical data, and its potential utility in combination with PD-1 inhibitors

Journal for immunotherapy of cancer, 2018-06, Vol.6 (1), p.54-13, Article 54

2018

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Damage‐Associated Molecular Patterns Induce Inflammatory Injury During Machine Preservation of the Liver: Potential Targets to Enhance a Promising Technology

Liver transplantation, 2019-04, Vol.25 (4), p.610-626

2019

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Circulating mitochondria in deceased organ donors are associated with immune activation and early allograft dysfunction

JCI insight, 2018-08, Vol.3 (15)

2018

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Generation of Luciferase-expressing Tumor Cell Lines

Bio-protocol, 2018-04, Vol.8 (8)

2018

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Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands

The Journal of clinical investigation, 2017-04, Vol.127 (4), p.1574-1588

2017

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Factors Associated With Detection and Survival of T1 Hepatocellular Carcinoma in the United States: National Cancer Database Analysis

Journal of the National Comprehensive Cancer Network, 2020-09, Vol.18 (9), p.1210-1220

2020

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Machine perfusion of donor kidneys may reduce graft rejection

Clinical transplantation, 2019-10, Vol.33 (10), p.e13716-n/a

2019

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IL‐7 receptor heterogeneity as a mechanism for repertoire change during postdepletional homeostatic proliferation and its relation to costimulation blockade–resistant rejection

American journal of transplantation, 2018-03, Vol.18 (3), p.720-730

2018

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Circulating mitochondria in organ donors promote allograft rejection

Higher thresholds for the utilization of steatotic allografts in liver transplantation: Analysis from a U.S. national database

Effects of Immunosuppressive Medications on Mitochondrial Function

Immunomodulatory Activities of the Heparan Sulfate Mimetic PG545

PD-L1 serves as a double agent in separating GVL from GVHD

GCNT1-Mediated O -Glycosylation of the Sialomucin CD43 Is a Sensitive Indicator of Notch Signaling in Activated T Cells

A Phase I study of the novel immunomodulatory agent PG545 (pixatimod) in subjects with advanced solid tumours

Heparan sulfate is a plasma biomarker of acute cellular allograft rejection

Graft-derived extracellular vesicles transported across subcapsular sinus macrophages elicit B cell alloimmunity after transplantation

Challenges, highlights, and opportunities in cellular transplantation: A white paper of the current landscape

Heparan sulfate mimetic PG545-mediated antilymphoma effects require TLR9-dependent NK cell activation

Modification of host dendritic cells by microchimerism-derived extracellular vesicles generates split tolerance

Heparan sulfate, an endogenous TLR4 agonist, promotes acute GVHD after allogeneic stem cell transplantation

Extracellular Mitochondrial DNA and N-Formyl Peptides in Trauma and Critical Illness: A Systematic Review

Early Notch Signals Induce a Pathogenic Molecular Signature during Priming of Alloantigen-Specific Conventional CD4 + T Cells in Graft-versus-Host Disease

Dendritic Cell Therapy in Transplantation, Phenotype Governs Destination and Function

Targeting Glycolysis in Alloreactive T Cells to Prevent Acute Graft- Versus -Host Disease While Preserving Graft-Versus-Leukemia Effect

Immunomodulatory activities of pixatimod: emerging nonclinical and clinical data, and its potential utility in combination with PD-1 inhibitors

Damage‐Associated Molecular Patterns Induce Inflammatory Injury During Machine Preservation of the Liver: Potential Targets to Enhance a Promising Technology

Circulating mitochondria in deceased organ donors are associated with immune activation and early allograft dysfunction

Generation of Luciferase-expressing Tumor Cell Lines

Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands

Factors Associated With Detection and Survival of T1 Hepatocellular Carcinoma in the United States: National Cancer Database Analysis

Machine perfusion of donor kidneys may reduce graft rejection

IL‐7 receptor heterogeneity as a mechanism for repertoire change during postdepletional homeostatic proliferation and its relation to costimulation blockade–resistant rejection

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