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The Manifold Cellular Functions of von Willebrand Factor

Cells (Basel, Switzerland), 2021-09, Vol.10 (9), p.2351

2021

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Force-Sensitive Autoinhibition of the von Willebrand Factor Is Mediated by Interdomain Interactions

Biophysical journal, 2015-05, Vol.108 (9), p.2312-2321

2015

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The von Willebrand factor Tyr2561 allele is a gain-of-function variant and a risk factor for early myocardial infarction

Blood, 2019-01, Vol.133 (4), p.356-365

2019

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Upshaw-Schulman syndrome-associated ADAMTS13 variants possess proteolytic activity at the surface of endothelial cells and in simulated circulation

PloS one, 2020-05, Vol.15 (5), p.e0232637-e0232637

2020

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von Willebrand factor is dimerized by protein disulfide isomerase

Blood, 2016-03, Vol.127 (9), p.1183-1191

2016

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Advancing multimer analysis of von Willebrand factor by single-molecule AFM imaging

PloS one, 2019-01, Vol.14 (1), p.e0210963-e0210963

2019

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von Willebrand disease type 2A phenotypes IIC, IID and IIE: A day in the life of shear-stressed mutant von Willebrand factor

Thrombosis and haemostasis, 2014, Vol.112 (1), p.96-108

2014

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Von Willebrand Factor Mediates Pneumococcal Aggregation and Adhesion in Blood Flow

Frontiers in microbiology, 2019-03, Vol.10, p.511-511

2019

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New options of cancer treatment employing InsP 6

Biochemical pharmacology, 2019-05, Vol.163, p.206

2019

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A biophysical view on von Willebrand factor activation

Journal of cellular physiology, 2018-02, Vol.233 (2), p.799-810

2018

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Multiplexed protein force spectroscopy reveals equilibrium protein folding dynamics and the low-force response of von Willebrand factor

Proceedings of the National Academy of Sciences - PNAS, 2019-09, Vol.116 (38), p.18798-18807

2019

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New options of cancer treatment employing InsP6

Biochemical pharmacology, 2019-05, Vol.163, p.206-214

2019

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Alteration in GPIIb/IIIa Binding of VWD-Associated von Willebrand Factor Variants with C-Terminal Missense Mutations

Thrombosis and haemostasis, 2019-07, Vol.119 (7), p.1102-1111

2019

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Intracellular localization of human Ins(1,3,4,5,6)P5 2-kinase

Biochemical journal, 2007-12, Vol.408 (3), p.335-345

2007

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Von Willebrand factor processing

Hämostaseologie, 2017-01, Vol.37 (1), p.59-72

Brehm, Maria A

2017

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DNA binds to a specific site of the adhesive blood-protein von Willebrand factor guided by electrostatic interactions

Nucleic acids research, 2020-07, Vol.48 (13), p.7333-7344

2020

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Gain-of-Function Variant p.Pro2555Arg of von Willebrand Factor Increases Aggregate Size through Altering Stem Dynamics

Thrombosis and haemostasis, 2022-02, Vol.122 (2), p.226-239

2022

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Structure and dynamics of the von Willebrand Factor C6 domain

Journal of structural biology, 2022-12, Vol.214 (4), p.107923-107923, Article 107923

2022

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Enhanced Local Disorder in a Clinically Elusive von Willebrand Factor Provokes High-Affinity Platelet Clumping

Journal of molecular biology, 2017-07, Vol.429 (14), p.2161-2177

2017

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Tumour cells can employ extracellular Ins(1,2,3,4,5,6) P 6 and multiple inositol-polyphosphate phosphatase 1 (MINPP1) dephosphorylation to improve their proliferation

Biochemical journal, 2013-02, Vol.450 (1), p.115-125

2013

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DNA binds to a specific site of the adhesive blood-protein von Willebrand factor guided by electrostatic interactions

Nucleic acids research, 2020-11, Vol.48 (20), p.11812-11813

2020

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Identification of the actin-binding domain of Ins(1,4,5)P3 3-kinase isoform B (IP3K-B)

Biochemical journal, 2004-08, Vol.382 (Pt 1), p.353-362

2004

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Single molecule force spectroscopy data and BD- and MD simulations on the blood protein von Willebrand factor

Data in brief, 2016-09, Vol.8, p.1080-1087

2016

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Evidence for the Misfolding of the A1 Domain within Multimeric von Willebrand Factor in Type 2 von Willebrand Disease

Journal of molecular biology, 2020-01, Vol.432 (2), p.305-323

2020

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Mutual A domain interactions in the force sensing protein von Willebrand factor

Journal of structural biology, 2017-01, Vol.197 (1), p.57-64

2017

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The Manifold Cellular Functions of von Willebrand Factor

Force-Sensitive Autoinhibition of the von Willebrand Factor Is Mediated by Interdomain Interactions

The von Willebrand factor Tyr2561 allele is a gain-of-function variant and a risk factor for early myocardial infarction

Upshaw-Schulman syndrome-associated ADAMTS13 variants possess proteolytic activity at the surface of endothelial cells and in simulated circulation

von Willebrand factor is dimerized by protein disulfide isomerase

Advancing multimer analysis of von Willebrand factor by single-molecule AFM imaging

von Willebrand disease type 2A phenotypes IIC, IID and IIE: A day in the life of shear-stressed mutant von Willebrand factor

Von Willebrand Factor Mediates Pneumococcal Aggregation and Adhesion in Blood Flow

New options of cancer treatment employing InsP 6

A biophysical view on von Willebrand factor activation

Multiplexed protein force spectroscopy reveals equilibrium protein folding dynamics and the low-force response of von Willebrand factor

New options of cancer treatment employing InsP6

Alteration in GPIIb/IIIa Binding of VWD-Associated von Willebrand Factor Variants with C-Terminal Missense Mutations

Intracellular localization of human Ins(1,3,4,5,6)P5 2-kinase

Von Willebrand factor processing

DNA binds to a specific site of the adhesive blood-protein von Willebrand factor guided by electrostatic interactions

Gain-of-Function Variant p.Pro2555Arg of von Willebrand Factor Increases Aggregate Size through Altering Stem Dynamics

Structure and dynamics of the von Willebrand Factor C6 domain

Enhanced Local Disorder in a Clinically Elusive von Willebrand Factor Provokes High-Affinity Platelet Clumping

Tumour cells can employ extracellular Ins(1,2,3,4,5,6) P 6 and multiple inositol-polyphosphate phosphatase 1 (MINPP1) dephosphorylation to improve their proliferation

DNA binds to a specific site of the adhesive blood-protein von Willebrand factor guided by electrostatic interactions

Identification of the actin-binding domain of Ins(1,4,5)P3 3-kinase isoform B (IP3K-B)

Single molecule force spectroscopy data and BD- and MD simulations on the blood protein von Willebrand factor

Evidence for the Misfolding of the A1 Domain within Multimeric von Willebrand Factor in Type 2 von Willebrand Disease

Mutual A domain interactions in the force sensing protein von Willebrand factor

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