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The Manifold Cellular Functions of von Willebrand Factor

Cells (Basel, Switzerland), 2021-09, Vol.10 (9), p.2351

2021

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Force-Sensitive Autoinhibition of the von Willebrand Factor Is Mediated by Interdomain Interactions

Biophysical journal, 2015-05, Vol.108 (9), p.2312-2321

2015

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The von Willebrand factor Tyr2561 allele is a gain-of-function variant and a risk factor for early myocardial infarction

Blood, 2019-01, Vol.133 (4), p.356-365

2019

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Upshaw-Schulman syndrome-associated ADAMTS13 variants possess proteolytic activity at the surface of endothelial cells and in simulated circulation

PloS one, 2020-05, Vol.15 (5), p.e0232637-e0232637

2020

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von Willebrand factor is dimerized by protein disulfide isomerase

Blood, 2016-03, Vol.127 (9), p.1183-1191

2016

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Advancing multimer analysis of von Willebrand factor by single-molecule AFM imaging

PloS one, 2019-01, Vol.14 (1), p.e0210963-e0210963

2019

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von Willebrand disease type 2A phenotypes IIC, IID and IIE: A day in the life of shear-stressed mutant von Willebrand factor

Thrombosis and haemostasis, 2014, Vol.112 (1), p.96

2014

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Von Willebrand Factor Mediates Pneumococcal Aggregation and Adhesion in Blood Flow

Frontiers in microbiology, 2019-03, Vol.10, p.511-511

2019

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New options of cancer treatment employing InsP 6

Biochemical pharmacology, 2019-05, Vol.163, p.206

2019

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A biophysical view on von Willebrand factor activation

Journal of cellular physiology, 2018-02, Vol.233 (2), p.799-810

2018

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Multiplexed protein force spectroscopy reveals equilibrium protein folding dynamics and the low-force response of von Willebrand factor

Proceedings of the National Academy of Sciences - PNAS, 2019-09, Vol.116 (38), p.18798-18807

2019

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New options of cancer treatment employing InsP6

Biochemical pharmacology, 2019-05, Vol.163, p.206-214

2019

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Alteration in GPIIb/IIIa Binding of VWD-Associated von Willebrand Factor Variants with C-Terminal Missense Mutations

Thrombosis and haemostasis, 2019-07, Vol.119 (7), p.1102

2019

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Intracellular localization of human Ins(1,3,4,5,6)P5 2-kinase

Biochemical journal, 2007-12, Vol.408 (3), p.335-345

2007

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Von Willebrand factor processing

Hämostaseologie, 2017-01, Vol.37 (1), p.59

Brehm, Maria A

2017

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Gain-of-Function Variant p.Pro2555Arg of von Willebrand Factor Increases Aggregate Size through Altering Stem Dynamics

Thrombosis and haemostasis, 2022-02, Vol.122 (2), p.226

2022

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Structure and dynamics of the von Willebrand Factor C6 domain

Journal of structural biology, 2022-12, Vol.214 (4), p.107923-107923, Article 107923

2022

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Enhanced Local Disorder in a Clinically Elusive von Willebrand Factor Provokes High-Affinity Platelet Clumping

Journal of molecular biology, 2017-07, Vol.429 (14), p.2161-2177

2017

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Identification of the actin-binding domain of Ins(1,4,5)P3 3-kinase isoform B (IP3K-B)

Biochemical journal, 2004-08, Vol.382 (Pt 1), p.353-362

2004

Volltextzugriff (PDF)

Single molecule force spectroscopy data and BD- and MD simulations on the blood protein von Willebrand factor

Data in brief, 2016-09, Vol.8, p.1080-1087

2016

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Evidence for the Misfolding of the A1 Domain within Multimeric von Willebrand Factor in Type 2 von Willebrand Disease

Journal of molecular biology, 2020-01, Vol.432 (2), p.305-323

2020

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Inositol hexakisphosphate increases the size of platelet aggregates

Biochemical pharmacology, 2019-03, Vol.161, p.14-25

2019

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Mutual A domain interactions in the force sensing protein von Willebrand factor

Journal of structural biology, 2017-01, Vol.197 (1), p.57-64

2017

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Efficacious inhibition of Importin α/β-mediated nuclear import of human inositol phosphate multikinase

Biochimie, 2014-07, Vol.102, p.117-123

2014

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Biophysical approaches promote advances in the understanding of von Willebrand factor processing and function

Advances in biological regulation, 2017-01, Vol.63, p.81-91

2017

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The Manifold Cellular Functions of von Willebrand Factor

Force-Sensitive Autoinhibition of the von Willebrand Factor Is Mediated by Interdomain Interactions

The von Willebrand factor Tyr2561 allele is a gain-of-function variant and a risk factor for early myocardial infarction

Upshaw-Schulman syndrome-associated ADAMTS13 variants possess proteolytic activity at the surface of endothelial cells and in simulated circulation

von Willebrand factor is dimerized by protein disulfide isomerase

Advancing multimer analysis of von Willebrand factor by single-molecule AFM imaging

von Willebrand disease type 2A phenotypes IIC, IID and IIE: A day in the life of shear-stressed mutant von Willebrand factor

Von Willebrand Factor Mediates Pneumococcal Aggregation and Adhesion in Blood Flow

New options of cancer treatment employing InsP 6

A biophysical view on von Willebrand factor activation

Multiplexed protein force spectroscopy reveals equilibrium protein folding dynamics and the low-force response of von Willebrand factor

New options of cancer treatment employing InsP6

Alteration in GPIIb/IIIa Binding of VWD-Associated von Willebrand Factor Variants with C-Terminal Missense Mutations

Intracellular localization of human Ins(1,3,4,5,6)P5 2-kinase

Von Willebrand factor processing

Gain-of-Function Variant p.Pro2555Arg of von Willebrand Factor Increases Aggregate Size through Altering Stem Dynamics

Structure and dynamics of the von Willebrand Factor C6 domain

Enhanced Local Disorder in a Clinically Elusive von Willebrand Factor Provokes High-Affinity Platelet Clumping

Identification of the actin-binding domain of Ins(1,4,5)P3 3-kinase isoform B (IP3K-B)

Single molecule force spectroscopy data and BD- and MD simulations on the blood protein von Willebrand factor

Evidence for the Misfolding of the A1 Domain within Multimeric von Willebrand Factor in Type 2 von Willebrand Disease

Inositol hexakisphosphate increases the size of platelet aggregates

Mutual A domain interactions in the force sensing protein von Willebrand factor

Efficacious inhibition of Importin α/β-mediated nuclear import of human inositol phosphate multikinase

Biophysical approaches promote advances in the understanding of von Willebrand factor processing and function

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