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A study of the reactivity of S (VI) -F containing warheads with nucleophilic amino-acid side chains under physiological conditions

Organic & biomolecular chemistry, 2017, Vol.15 (45), p.9685-9695

2017

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Structural Characterisation Reveals Mechanism of IL-13-Neutralising Monoclonal Antibody Tralokinumab as Inhibition of Binding to IL-13Rα1 and IL-13Rα2

Journal of molecular biology, 2017-01, Vol.429 (2), p.208-219

2017

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Putting patients at the center of kidney care transitions: PREPARE NOW, a cluster randomized controlled trial

Contemporary clinical trials, 2018-10, Vol.73, p.98-110

2018

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Phase Ib Trial of Intravenous Recombinant Humanized Monoclonal Antibody to Vascular Endothelial Growth Factor in Combination With Chemotherapy in Patients With Advanced Cancer: Pharmacologic and Long-Term Safety Data

Journal of clinical oncology, 2001-02, Vol.19 (3), p.851-856

2001

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Cation-π Interactions as Determinants for Binding of the Compatible Solutes Glycine Betaine and Proline Betaine by the Periplasmic Ligand-binding Protein ProX from Escherichia coli

The Journal of biological chemistry, 2004-02, Vol.279 (7), p.5588-5596

2004

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A novel method for structure-based prediction of ion channel conductance properties

Biophysical journal, 1997-03, Vol.72 (3), p.1109-1126

1997

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Improved Prognosis of Patients With Primary Biliary Cirrhosis That Have a Biochemical Response to Ursodeoxycholic Acid

Gastroenterology (New York, N.Y. 1943), 2009-04, Vol.136 (4), p.1281-1287

2009

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Discovery of AZD4747, a Potent and Selective Inhibitor of Mutant GTPase KRAS G12C with Demonstrable CNS Penetration

Journal of medicinal chemistry, 2023-07, Vol.66 (13), p.9147-9160

2023

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Discovery of AZD4747, a Potent and Selective Inhibitor of Mutant GTPase KRASG12C with Demonstrable CNS Penetration

Journal of medicinal chemistry, 2023-07, Vol.66 (13), p.9147-9160

2023

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Prediction by a neural network of outer membrane β‐strand protein topology

Protein science, 1998-11, Vol.7 (11), p.2413-2420

1998

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Water in channel-like cavities: structure and dynamics

Biophysical journal, 1996-02, Vol.70 (2), p.693-702

1996

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Characterising older adults’ risk of harm from blood-pressure lowering medications: a sub-analysis from the PRIME study

Age and ageing, 2022-03, Vol.51 (3)

2022

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A study of the reactivity of S(VI)-F containing warheads with nucleophilic amino-acid side chains under physiological conditionsElectronic supplementary information (ESI) available. See DOI: 10.1039/c7ob02028g

2017-11

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Molecular dynamics simulations of water within models of ion channels

Biophysical journal, 1996-04, Vol.70 (4), p.1643-1661

1996

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Simulation Studies of Alamethicin-Bilayer Interactions

Biophysical journal, 1997-02, Vol.72 (2), p.627-636

1997

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Effects of antihypertensive treatment after acute stroke in the Continue Or Stop post-Stroke Antihypertensives Collaborative Study (COSSACS): a prospective, randomised, open, blinded-endpoint trial

Lancet neurology, 2010-08, Vol.9 (8), p.767-775

2010

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Three-Dimensional Structure of the Nonaheme Cytochrome c from Desulfovibrio desulfuricans Essex in the Fe(III) State at 1.89 Å Resolution

Biochemistry (Easton), 2001-02, Vol.40 (5), p.1308-1316

2001

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Pharmacokinetics of a slower clearing tissue plasminogen activator variant, TNK-tPA, in patients with acute myocardial infarction

Thrombosis and haemostasis, 1998-01, Vol.79 (1), p.134-139

1998

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The influence of perindopril and the diuretic combination amiloride + hydrochlorothiazide on the vessel wall properties of large arteries in hypertensive patients

Journal of hypertension, 1995-08, Vol.13 (8), p.839-848

1995

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Purification, crystallization and preliminary crystallographic analysis of the periplasmic binding protein ProX from Escherichia coli

Acta crystallographica. Section D, Biological crystallography., 2001-03, Vol.57 (3), p.448-450

2001

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SAR and inhibitor complex structure determination of a novel class of potent and specific Aurora kinase inhibitors

Bioorganic & medicinal chemistry letters, 2006-03, Vol.16 (5), p.1320-1323

2006

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An internal affinity‐tag for purification and crystallization of the siderophore receptor fhua, integral outer membrane protein from escherichia coli K‐12

Protein science, 1998-07, Vol.7 (7), p.1636-1638

1998

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Molecular Determinants for Substrate Specificity of the Ligand-binding Protein OpuAC from Bacillus subtilis for the Compatible Solutes Glycine Betaine and Proline Betaine

Journal of molecular biology, 2006-03, Vol.357 (2), p.592-606

2006

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The structure of porin from Paracoccus denitrificans at 3.1 Å resolution

FEBS letters, 1997-03, Vol.404 (2), p.208-210

1997

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A randomized trial in primary biliary cirrhosis comparing ursodeoxycholic acid in daily doses of either 10 mg/kg or 20 mg/kg

Alimentary pharmacology & therapeutics, 1998-10, Vol.12 (10), p.965-971

1998

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A study of the reactivity of S (VI) -F containing warheads with nucleophilic amino-acid side chains under physiological conditions

Structural Characterisation Reveals Mechanism of IL-13-Neutralising Monoclonal Antibody Tralokinumab as Inhibition of Binding to IL-13Rα1 and IL-13Rα2

Putting patients at the center of kidney care transitions: PREPARE NOW, a cluster randomized controlled trial

Phase Ib Trial of Intravenous Recombinant Humanized Monoclonal Antibody to Vascular Endothelial Growth Factor in Combination With Chemotherapy in Patients With Advanced Cancer: Pharmacologic and Long-Term Safety Data

Cation-π Interactions as Determinants for Binding of the Compatible Solutes Glycine Betaine and Proline Betaine by the Periplasmic Ligand-binding Protein ProX from Escherichia coli

A novel method for structure-based prediction of ion channel conductance properties

Improved Prognosis of Patients With Primary Biliary Cirrhosis That Have a Biochemical Response to Ursodeoxycholic Acid

Discovery of AZD4747, a Potent and Selective Inhibitor of Mutant GTPase KRAS G12C with Demonstrable CNS Penetration

Discovery of AZD4747, a Potent and Selective Inhibitor of Mutant GTPase KRASG12C with Demonstrable CNS Penetration

Prediction by a neural network of outer membrane β‐strand protein topology

Water in channel-like cavities: structure and dynamics

Characterising older adults’ risk of harm from blood-pressure lowering medications: a sub-analysis from the PRIME study

A study of the reactivity of S(VI)-F containing warheads with nucleophilic amino-acid side chains under physiological conditionsElectronic supplementary information (ESI) available. See DOI: 10.1039/c7ob02028g

Molecular dynamics simulations of water within models of ion channels

Simulation Studies of Alamethicin-Bilayer Interactions

Effects of antihypertensive treatment after acute stroke in the Continue Or Stop post-Stroke Antihypertensives Collaborative Study (COSSACS): a prospective, randomised, open, blinded-endpoint trial

Three-Dimensional Structure of the Nonaheme Cytochrome c from Desulfovibrio desulfuricans Essex in the Fe(III) State at 1.89 Å Resolution

Pharmacokinetics of a slower clearing tissue plasminogen activator variant, TNK-tPA, in patients with acute myocardial infarction

The influence of perindopril and the diuretic combination amiloride + hydrochlorothiazide on the vessel wall properties of large arteries in hypertensive patients

Purification, crystallization and preliminary crystallographic analysis of the periplasmic binding protein ProX from Escherichia coli

SAR and inhibitor complex structure determination of a novel class of potent and specific Aurora kinase inhibitors

An internal affinity‐tag for purification and crystallization of the siderophore receptor fhua, integral outer membrane protein from escherichia coli K‐12

Molecular Determinants for Substrate Specificity of the Ligand-binding Protein OpuAC from Bacillus subtilis for the Compatible Solutes Glycine Betaine and Proline Betaine

The structure of porin from Paracoccus denitrificans at 3.1 Å resolution

A randomized trial in primary biliary cirrhosis comparing ursodeoxycholic acid in daily doses of either 10 mg/kg or 20 mg/kg

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