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The impact of cytokines on the expression of drug transporters, cytochrome P450 enzymes and chemokine receptors in human PBMC

British journal of pharmacology, 2009-02, Vol.156 (3), p.497-508

2009

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Artemisinins target the SERCA of Plasmodium falciparum

Nature, 2003-08, Vol.424 (6951), p.957-961

2003

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Defining the role of PfCRT in Plasmodium falciparum chloroquine resistance

Molecular microbiology, 2005-04, Vol.56 (2), p.323-333

2005

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Evidence for a Central Role for PfCRT in Conferring Plasmodium falciparum Resistance to Diverse Antimalarial Agents

Molecular cell, 2004-09, Vol.15 (6), p.867-877

2004

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Pentamidine uptake and resistance in pathogenic protozoa: past, present and future

Trends in parasitology, 2003-05, Vol.19 (5), p.232-239

2003

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Functional Characterization and Target Validation of Alternative Complex I of Plasmodium falciparum Mitochondria

Antimicrobial Agents and Chemotherapy, 2006-05, Vol.50 (5), p.1841-1851

2006

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A critical role for PfCRT K76T in Plasmodium falciparum verapamil-reversible chloroquine resistance

The EMBO journal, 2005-07, Vol.24 (13), p.2294-2305

2005

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Modulation of the intracellular accumulation of saquinavir in peripheral blood mononuclear cells by inhibitors of MRP1, MRP2, P-gp and BCRP

AIDS (London), 2005-12, Vol.19 (18), p.2097-2102

2005

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Quinolines and artemisinin: chemistry, biology and history

Current topics in microbiology and immunology, 2005, Vol.295, p.3

2005

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Acidification of the Malaria Parasite's Digestive Vacuole by a H+-ATPase and a H+-pyrophosphatase

The Journal of biological chemistry, 2003-02, Vol.278 (8), p.5605-5612

2003

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Novel Short Chain Chloroquine Analogues Retain Activity Against Chloroquine Resistant K1 Plasmodium falciparum

Journal of medicinal chemistry, 2002-11, Vol.45 (23), p.4975-4983

2002

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Primaquine synergises the activity of chloroquine against chloroquine-resistant P. falciparum

Biochemical pharmacology, 2005-10, Vol.70 (8), p.1158-1166

2005

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P-glycoprotein and transporter MRP1 reduce HIV protease inhibitor uptake in CD4 cells : potential for accelerated viral drug resistance?

AIDS (London), 2001-07, Vol.15 (11), p.1353-1358

2001

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Isoquine and Related Amodiaquine Analogues: A New Generation of Improved 4-Aminoquinoline Antimalarials

Journal of medicinal chemistry, 2003-11, Vol.46 (23), p.4933-4945

2003

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Antimalarial and Antitumor Evaluation of Novel C-10 Non-Acetal Dimers of 10β-(2-Hydroxyethyl)deoxoartemisinin

Journal of medicinal chemistry, 2004-02, Vol.47 (5), p.1290-1298

2004

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Antimalarial chemotherapy: young guns or back to the future?

Trends in parasitology, 2003-11, Vol.19 (11), p.479-487

2003

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Heme Binding Contributes to Antimalarial Activity of Bis-Quaternary Ammoniums

Antimicrobial Agents and Chemotherapy, 2003-08, Vol.47 (8), p.2584-2589

2003

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Access to Hematin: The Basis of Chloroquine Resistance

Molecular pharmacology, 1998-07, Vol.54 (1), p.170-179

1998

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Towards a proteomic definition of CoArtem action in Plasmodium falciparum malaria

Proteomics (Weinheim), 2005-05, Vol.5 (7), p.1849-1858

2005

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4-Aminoquinolines—Past, present, and future; A chemical perspective

Pharmacology & therapeutics (Oxford), 1998, Vol.77 (1), p.29-58

1998

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Mechanism-Based Design of Parasite-Targeted Artemisinin Derivatives: Synthesis and Antimalarial Activity of New Diamine Containing Analogues

Journal of medicinal chemistry, 2002-02, Vol.45 (5), p.1052-1063

2002

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Cellular Uptake of Chloroquine Is Dependent on Binding to Ferriprotoporphyrin IX and Is Independent of NHE Activity in Plasmodium falciparum

The Journal of cell biology, 1999-04, Vol.145 (2), p.363-376

1999

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A Requiem for Chloroquine

Science (American Association for the Advancement of Science), 2002-10, Vol.298 (5591), p.74-75

2002

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The Digestive Food Vacuole of the Malaria Parasite Is a Dynamic Intracellular Ca2+ Store

The Journal of biological chemistry, 2003-07, Vol.278 (30), p.27910-27915

2003

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Enantiomeric 1,2,4-Trioxanes Display Equivalent in vitro Antimalarial Activity Versus Plasmodium falciparum Malaria Parasites: Implications for the Molecular Mechanism of Action of the Artemisinins

Chembiochem : a European journal of chemical biology, 2005-11, Vol.6 (11), p.2048-2054

2005

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The impact of cytokines on the expression of drug transporters, cytochrome P450 enzymes and chemokine receptors in human PBMC

Artemisinins target the SERCA of Plasmodium falciparum

Defining the role of PfCRT in Plasmodium falciparum chloroquine resistance

Evidence for a Central Role for PfCRT in Conferring Plasmodium falciparum Resistance to Diverse Antimalarial Agents

Pentamidine uptake and resistance in pathogenic protozoa: past, present and future

Functional Characterization and Target Validation of Alternative Complex I of Plasmodium falciparum Mitochondria

A critical role for PfCRT K76T in Plasmodium falciparum verapamil-reversible chloroquine resistance

Modulation of the intracellular accumulation of saquinavir in peripheral blood mononuclear cells by inhibitors of MRP1, MRP2, P-gp and BCRP

Quinolines and artemisinin: chemistry, biology and history

Acidification of the Malaria Parasite's Digestive Vacuole by a H+-ATPase and a H+-pyrophosphatase

Novel Short Chain Chloroquine Analogues Retain Activity Against Chloroquine Resistant K1 Plasmodium falciparum

Primaquine synergises the activity of chloroquine against chloroquine-resistant P. falciparum

P-glycoprotein and transporter MRP1 reduce HIV protease inhibitor uptake in CD4 cells : potential for accelerated viral drug resistance?

Isoquine and Related Amodiaquine Analogues: A New Generation of Improved 4-Aminoquinoline Antimalarials

Antimalarial and Antitumor Evaluation of Novel C-10 Non-Acetal Dimers of 10β-(2-Hydroxyethyl)deoxoartemisinin

Antimalarial chemotherapy: young guns or back to the future?

Heme Binding Contributes to Antimalarial Activity of Bis-Quaternary Ammoniums

Access to Hematin: The Basis of Chloroquine Resistance

Towards a proteomic definition of CoArtem action in Plasmodium falciparum malaria

4-Aminoquinolines—Past, present, and future; A chemical perspective

Mechanism-Based Design of Parasite-Targeted Artemisinin Derivatives: Synthesis and Antimalarial Activity of New Diamine Containing Analogues

Cellular Uptake of Chloroquine Is Dependent on Binding to Ferriprotoporphyrin IX and Is Independent of NHE Activity in Plasmodium falciparum

A Requiem for Chloroquine

The Digestive Food Vacuole of the Malaria Parasite Is a Dynamic Intracellular Ca2+ Store

Enantiomeric 1,2,4-Trioxanes Display Equivalent in vitro Antimalarial Activity Versus Plasmodium falciparum Malaria Parasites: Implications for the Molecular Mechanism of Action of the Artemisinins

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