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Schizophrenia Genomics: Convergence on Synaptic Development, Adult Synaptic Plasticity, or Both?

Biological psychiatry (1969), 2022-04, Vol.91 (8), p.709-717

2022

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Methylomic profiling of human brain tissue supports a neurodevelopmental origin for schizophrenia

Genome biology, 2014-01, Vol.15 (10), p.483-483, Article 483

2014

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Methylomic trajectories across human fetal brain development

Genome research, 2015-03, Vol.25 (3), p.338-352

2015

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Psychosis Risk Candidate ZNF804A Localizes to Synapses and Regulates Neurite Formation and Dendritic Spine Structure

Biological psychiatry (1969), 2017-07, Vol.82 (1), p.49-61

2017

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Methylation QTLs in the developing brain and their enrichment in schizophrenia risk loci

Nature neuroscience, 2016-01, Vol.19 (1), p.48-54

2016

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5-hydroxymethylcytosine is highly dynamic across human fetal brain development

BMC genomics, 2017-09, Vol.18 (1), p.738-738, Article 738

2017

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CRISPR–Cas9 genome editing in human cells occurs via the Fanconi anemia pathway

Nature genetics, 2018-08, Vol.50 (8), p.1132-1139

2018

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Expression quantitative trait loci in the developing human brain and their enrichment in neuropsychiatric disorders

Genome Biology, 2018-11, Vol.19 (1), p.194-194, Article 194

2018

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Full-length transcript sequencing of human and mouse cerebral cortex identifies widespread isoform diversity and alternative splicing

Cell reports (Cambridge), 2021-11, Vol.37 (7), p.110022-110022, Article 110022

2021

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Evidence That Schizophrenia Risk Variation in the ZNF804A Gene Exerts Its Effects During Fetal Brain Development

The American journal of psychiatry, 2012-12, Vol.169 (12), p.1301-1308

2012

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Mapping microRNA expression quantitative trait loci in the prenatal human brain implicates miR-1908-5p expression in bipolar disorder and other brain-related traits

Human molecular genetics, 2023-10, Vol.32 (20), p.2941-2949

2023

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Novel Insight Into the Etiology of Autism Spectrum Disorder Gained by Integrating Expression Data With Genome-wide Association Statistics

Biological psychiatry (1969), 2019-08, Vol.86 (4), p.265-273

2019

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Single-Nuclei RNA Sequencing of 5 Regions of the Human Prenatal Brain Implicates Developing Neuron Populations in Genetic Risk for Schizophrenia

Biological psychiatry (1969), 2023-01, Vol.93 (2), p.157-166

2023

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A Developmental Perspective on the Convergence of Genetic Risk Factors for Neuropsychiatric Disorders

Biological psychiatry (1969), 2020-01, Vol.87 (2), p.98-99

2020

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Genetic Implication of Prenatal GABAergic and Cholinergic Neuron Development in Susceptibility to Schizophrenia

Schizophrenia bulletin, 2024-06, Vol.50 (5), p.1171-1184

2024

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A transcriptome-wide association study implicates specific pre- and post-synaptic abnormalities in schizophrenia

Human molecular genetics, 2020-01, Vol.29 (1), p.159-167

2020

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Cis-effects on gene expression in the human prenatal brain associated with genetic risk for neuropsychiatric disorders

Molecular psychiatry, 2021-06, Vol.26 (6), p.2082-2088

2021

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The Psychiatric Risk Gene NT5C2 Regulates Adenosine Monophosphate-Activated Protein Kinase Signaling and Protein Translation in Human Neural Progenitor Cells

Biological psychiatry (1969), 2019-07, Vol.86 (2), p.120-130

2019

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WED 139 Gene expression regulation in CD4+ t-cell dysfunction in ms

Journal of neurology, neurosurgery and psychiatry, 2018-10, Vol.89 (10), p.A16-A16

2018

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Exercise behaviors and resource use among graduate students at a Canadian university: A cross-sectional study

Journal of American college health, 2023-10, Vol.71 (8), p.2339-2346

2023

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Sites of active gene regulation in the prenatal frontal cortex and their role in neuropsychiatric disorders

American journal of medical genetics. Part B, Neuropsychiatric genetics, 2021-09, Vol.186 (6), p.376-388

2021

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Novel epigenetic clock for fetal brain development predicts prenatal age for cellular stem cell models and derived neurons

Molecular brain, 2021-06, Vol.14 (1), p.98-98, Article 98

2021

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Knockdown of the schizophrenia susceptibility gene TCF4 alters gene expression and proliferation of progenitor cells from the developing human neocortex

Journal of psychiatry & neuroscience, 2017-05, Vol.42 (3), p.181-188

2017

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Genome-wide significant schizophrenia risk variation on chromosome 10q24 is associated with altered cis-regulation of BORCS7, AS3MT, and NT5C2 in the human brain

American journal of medical genetics. Part B, Neuropsychiatric genetics, 2016-09, Vol.171B (6), p.806-814

2016

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Transcriptional consequences of schizophrenia candidate miR-137 manipulation in human neural progenitor cells

Schizophrenia research, 2014-03, Vol.153 (1), p.225-230

2014

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Schizophrenia Genomics: Convergence on Synaptic Development, Adult Synaptic Plasticity, or Both?

Methylomic profiling of human brain tissue supports a neurodevelopmental origin for schizophrenia

Methylomic trajectories across human fetal brain development

Psychosis Risk Candidate ZNF804A Localizes to Synapses and Regulates Neurite Formation and Dendritic Spine Structure

Methylation QTLs in the developing brain and their enrichment in schizophrenia risk loci

5-hydroxymethylcytosine is highly dynamic across human fetal brain development

CRISPR–Cas9 genome editing in human cells occurs via the Fanconi anemia pathway

Expression quantitative trait loci in the developing human brain and their enrichment in neuropsychiatric disorders

Full-length transcript sequencing of human and mouse cerebral cortex identifies widespread isoform diversity and alternative splicing

Evidence That Schizophrenia Risk Variation in the ZNF804A Gene Exerts Its Effects During Fetal Brain Development

Mapping microRNA expression quantitative trait loci in the prenatal human brain implicates miR-1908-5p expression in bipolar disorder and other brain-related traits

Novel Insight Into the Etiology of Autism Spectrum Disorder Gained by Integrating Expression Data With Genome-wide Association Statistics

Single-Nuclei RNA Sequencing of 5 Regions of the Human Prenatal Brain Implicates Developing Neuron Populations in Genetic Risk for Schizophrenia

A Developmental Perspective on the Convergence of Genetic Risk Factors for Neuropsychiatric Disorders

Genetic Implication of Prenatal GABAergic and Cholinergic Neuron Development in Susceptibility to Schizophrenia

A transcriptome-wide association study implicates specific pre- and post-synaptic abnormalities in schizophrenia

Cis-effects on gene expression in the human prenatal brain associated with genetic risk for neuropsychiatric disorders

The Psychiatric Risk Gene NT5C2 Regulates Adenosine Monophosphate-Activated Protein Kinase Signaling and Protein Translation in Human Neural Progenitor Cells

WED 139 Gene expression regulation in CD4+ t-cell dysfunction in ms

Exercise behaviors and resource use among graduate students at a Canadian university: A cross-sectional study

Sites of active gene regulation in the prenatal frontal cortex and their role in neuropsychiatric disorders

Novel epigenetic clock for fetal brain development predicts prenatal age for cellular stem cell models and derived neurons

Knockdown of the schizophrenia susceptibility gene TCF4 alters gene expression and proliferation of progenitor cells from the developing human neocortex

Genome-wide significant schizophrenia risk variation on chromosome 10q24 is associated with altered cis-regulation of BORCS7, AS3MT, and NT5C2 in the human brain

Transcriptional consequences of schizophrenia candidate miR-137 manipulation in human neural progenitor cells

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