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Regulation of the intrinsic apoptosis pathway by reactive oxygen species

Antioxidants & redox signaling, 2013-08, Vol.19 (6), p.546-558

2013

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Regulation of the Apaf-1-caspase-9 apoptosome

Journal of cell science, 2010-10, Vol.123 (19), p.3209-3214

2010

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The Apaf-1 apoptosome induces formation of caspase-9 homo- and heterodimers with distinct activities

Nature communications, 2016-11, Vol.7 (1), p.13565-14, Article 13565

2016

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The E3 Ubiquitin Ligase cIAP1 Binds and Ubiquitinates Caspase-3 and -7 via Unique Mechanisms at Distinct Steps in Their Processing

The Journal of biological chemistry, 2009-05, Vol.284 (19), p.12772-12782

2009

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Unexpected inhibition of the lipid kinase PIKfyve reveals an epistatic role for p38 MAPKs in endolysosomal fission and volume control

Cell death & disease, 2024-01, Vol.15 (1), p.80-80, Article 80

2024

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Caspase-dependent regulation of the ubiquitin–proteasome system through direct substrate targeting

Proceedings of the National Academy of Sciences - PNAS, 2013-08, Vol.110 (35), p.14284-14289

2013

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BH3-only protein BIM mediates heat shock-induced apoptosis

PloS one, 2014-01, Vol.9 (1), p.e84388

2014

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Proteasome-mediated Degradation of Smac during Apoptosis: XIAP Promotes Smac Ubiquitination in Vitro

The Journal of biological chemistry, 2002-09, Vol.277 (39), p.36611-36616

2002

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The Apaf-1 apoptosome: a large caspase-activating complex

Biochimie, 2002-02, Vol.84 (2), p.203-214

2002

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Mitochondrial uncoupling links lipid catabolism to Akt inhibition and resistance to tumorigenesis

Nature communications, 2015-08, Vol.6 (1), p.8137, Article 8137

2015

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Bcl-2 and Bcl-xL Inhibit CD95-mediated Apoptosis by Preventing Mitochondrial Release of Smac/DIABLO and Subsequent Inactivation of X-linked Inhibitor-of-Apoptosis Protein

The Journal of biological chemistry, 2002-03, Vol.277 (13), p.11345-11351

2002

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Heat Shock Induces Apoptosis Independently of Any Known Initiator Caspase-activating Complex

The Journal of biological chemistry, 2006-06, Vol.281 (25), p.16991-17000

2006

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Caspase-9 swings both ways in the apoptosome

Molecular & cellular oncology, 2017-03, Vol.4 (2), p.e1281865-e1281865

2017

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The role of E3 ligases in the ubiquitin-dependent regulation of spermatogenesis

Seminars in cell & developmental biology, 2014-06, Vol.30, p.27-35

2014

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Uncoupling of the Signaling and Caspase-inhibitory Properties of X-linked Inhibitor of Apoptosis

The Journal of biological chemistry, 2004-03, Vol.279 (10), p.9023-9029

2004

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The Apaf-1procaspase-9 apoptosome complex functions as a proteolytic-based molecular timer

The EMBO journal, 2009-07, Vol.28 (13), p.1916-1925

2009

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ATG5 cancer mutations and alternative mRNA splicing reveal a conjugation switch that regulates ATG12-ATG5-ATG16L1 complex assembly and autophagy

Cell discovery, 2019-08, Vol.5 (1), p.42-19, Article 42

2019

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Nuclear Factor-κB-inducing Kinase (NIK) Contains an Amino-terminal Inhibitor of Apoptosis (IAP)-binding Motif (IBM) That Potentiates NIK Degradation by Cellular IAP1 (c-IAP1)

The Journal of biological chemistry, 2014-10, Vol.289 (44), p.30680-30689

2014

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Peptide inhibitors: Four of a kind beats a pair

Nature chemical biology, 2012-06, Vol.8 (7), p.606

Bratton, Shawn B

2012

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Four of a kind beats a pair

Nature chemical biology, 2012-06, Vol.8 (7), p.606-607

Bratton, Shawn B

2012

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Thymoquinone inhibits autophagy and induces cathepsin-mediated, caspase-independent cell death in glioblastoma cells

PloS one, 2013-09, Vol.8 (9), p.e72882

2013

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Redox modulation of NQO1

PloS one, 2018-01, Vol.13 (1), p.e0190717-e0190717

2018

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Pseudomonas aeruginosa induces p38MAP kinase-dependent IL-6 and CXCL8 release from bronchial epithelial cells via a Syk kinase pathway

PloS one, 2021-02, Vol.16 (2), p.e0246050-e0246050

2021

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DrICE resurrects Grim to antagonize DIAP1

Cell cycle (Georgetown, Tex.), 2014-03, Vol.13 (5), p.685-686

2014

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Recruitment, activation and retention of caspases-9 and -3 by Apaf-1 apoptosome and associated XIAP complexes

The EMBO journal, 2001-03, Vol.20 (5), p.998-1009

2001

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Regulation of the intrinsic apoptosis pathway by reactive oxygen species

Regulation of the Apaf-1-caspase-9 apoptosome

The Apaf-1 apoptosome induces formation of caspase-9 homo- and heterodimers with distinct activities

The E3 Ubiquitin Ligase cIAP1 Binds and Ubiquitinates Caspase-3 and -7 via Unique Mechanisms at Distinct Steps in Their Processing

Unexpected inhibition of the lipid kinase PIKfyve reveals an epistatic role for p38 MAPKs in endolysosomal fission and volume control

Caspase-dependent regulation of the ubiquitin–proteasome system through direct substrate targeting

BH3-only protein BIM mediates heat shock-induced apoptosis

Proteasome-mediated Degradation of Smac during Apoptosis: XIAP Promotes Smac Ubiquitination in Vitro

The Apaf-1 apoptosome: a large caspase-activating complex

Mitochondrial uncoupling links lipid catabolism to Akt inhibition and resistance to tumorigenesis

Bcl-2 and Bcl-xL Inhibit CD95-mediated Apoptosis by Preventing Mitochondrial Release of Smac/DIABLO and Subsequent Inactivation of X-linked Inhibitor-of-Apoptosis Protein

Heat Shock Induces Apoptosis Independently of Any Known Initiator Caspase-activating Complex

Caspase-9 swings both ways in the apoptosome

The role of E3 ligases in the ubiquitin-dependent regulation of spermatogenesis

Uncoupling of the Signaling and Caspase-inhibitory Properties of X-linked Inhibitor of Apoptosis

The Apaf-1procaspase-9 apoptosome complex functions as a proteolytic-based molecular timer

ATG5 cancer mutations and alternative mRNA splicing reveal a conjugation switch that regulates ATG12-ATG5-ATG16L1 complex assembly and autophagy

Nuclear Factor-κB-inducing Kinase (NIK) Contains an Amino-terminal Inhibitor of Apoptosis (IAP)-binding Motif (IBM) That Potentiates NIK Degradation by Cellular IAP1 (c-IAP1)

Peptide inhibitors: Four of a kind beats a pair

Four of a kind beats a pair

Thymoquinone inhibits autophagy and induces cathepsin-mediated, caspase-independent cell death in glioblastoma cells

Redox modulation of NQO1

Pseudomonas aeruginosa induces p38MAP kinase-dependent IL-6 and CXCL8 release from bronchial epithelial cells via a Syk kinase pathway

DrICE resurrects Grim to antagonize DIAP1

Recruitment, activation and retention of caspases-9 and -3 by Apaf-1 apoptosome and associated XIAP complexes

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