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(6-Maleimidocaproyl)hydrazone of doxorubicin. A new derivative for the preparation of immunoconjugates of doxorubicin

Bioconjugate chemistry, 1993-11, Vol.4 (6), p.521-527

1993

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Evaluation in vitro of adriamycin immunoconjugates synthesized using an acid-sensitive hydrazone linker

Cancer research (Chicago, Ill.), 1990-10, Vol.50 (20), p.6600-6607

1990

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Effect of linker variation on the stability, potency, and efficacy of carcinoma-reactive BR64-doxorubicin immunoconjugates

Cancer research (Chicago, Ill.), 1997, Vol.57 (1), p.100-105

1997

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Future approaches for treating hematologic disease

Current pharmaceutical biotechnology, 2001-12, Vol.2 (4), p.369-382

2001

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Enhancement of cell-mediated immunity in melanoma patients immunized with murine anti-idiotypic monoclonal antibodies (MELIMMUNE) that mimic the high molecular weight proteoglycan antigen

Clinical cancer research, 1998-10, Vol.4 (10), p.2363-2370

1998

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Antitumor activity of adriamycin (hydrazone-linked) immunoconjugates compared with free adriamycin and specificity of tumor cell killing

Cancer research (Chicago, Ill.), 1990-10, Vol.50 (20), p.6608-6614

1990

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New hydrazone derivatives of Adriamycin and their immunoconjugates - a correlation between acid stability and cytotoxicity

Bioconjugate chemistry, 1991-05, Vol.2 (3), p.133-141

1991

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Adriamycin(hydrazone)-antibody conjugates require internalization and intracellular acid hydrolysis for antitumor activity

Cancer Immunology Immunotherapy, 1991-11, Vol.33 (6), p.367-374

1991

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Synthesis and antitumor activity of the immunoconjugate BR96-Dox

Journal of controlled release, 1996-05, Vol.39 (2), p.251-259

1996

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Antibody therapy of non-Hodgkin's B-cell lymphoma

Cancer Immunology, Immunotherapy, 2003-05, Vol.52 (5), p.257-280

2003

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Antigen-specific activity of carcinoma-reactive BR64-doxorubicin conjugates evaluated in vitro and in human tumor xenograft models

Cancer research (Chicago, Ill.), 1992-10, Vol.52 (20), p.5693-5700

1992

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Cytotoxicity of chimeric (human-murine) monoclonal antibody BR96 IgG, F(ab')2, and Fab' conjugated to Pseudomonas exotoxin

Bioconjugate chemistry, 1992-07, Vol.3 (4), p.302-307

1992

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Identification of functional domains in murine granulocyte-macrophage colony-stimulating factor using monoclonal antibodies to synthetic peptides

The Journal of immunology (1950), 1993-06, Vol.150 (12), p.5241-5251

1993

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The structure of an antitumor C(H)2-domain-deleted humanized antibody

Journal of molecular biology, 2005-05, Vol.348 (5), p.1177-1190

2005

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Granulocyte-macrophage colony-stimulating factor plays a role in the functional activity of mast cells

Journal of leukocyte biology, 1993-12, Vol.54 (6), p.523-527

1993

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The Structure of an Antitumor C sub(H)2-domain-deleted Humanized Antibody

Journal of molecular biology, 2005-05, Vol.348 (5), p.1177-1190

2005

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Combined use of AFM and X-ray diffraction to analyze crystals of an engineered, domain-deleted antibody

Acta crystallographica. Section D, Biological crystallography., 2005-04, Vol.61 (4), p.416-422

2005

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Modification of the Fc Region of a Primatized IgG Antibody to Human CD4 Retains Its Ability to Modulate CD4 Receptors but Does Not Deplete CD4+ T Cells in Chimpanzees

Clinical immunology (Orlando, Fla.), 2001-02, Vol.98 (2), p.164-174

2001

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The induction of cytotoxic T cells and tumor regression by soluble antigen formulation

Cancer research (Chicago, Ill.), 1995-08, Vol.55 (16), p.3486-3489

1995

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Determination of immunoreactivity of doxorubicin antibody immunoconjugates by a Ley competitive RIA

Bioconjugate chemistry, 1992-11, Vol.3 (6), p.549-553

1992

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Induction of differentiation of human promyelocytic leukemia (HL-60) cells by teleocidin and phorbol-12-myristate-13-acetate

Carcinogenesis (New York), 1982, Vol.3 (1), p.111-114

1982

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Tumor regression in mice following vaccination with human papillomavirus E7 recombinant protein in PROVAX

International journal of oncology, 1998-06, Vol.12 (6), p.1229

1998

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Direct binding of radioiodinated monoclonal antibody to tumor cells: significance of antibody purity and affinity for drug targeting or tumor imaging

Hybridoma, 1983, Vol.2 (3), p.297-310

1983

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Receptors for immune complexes on cells within a non-lymphoid murine tumor

The Journal of immunology (1950), 1976-06, Vol.116 (6), p.1571-1578

1976

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Monoclonal antibodies directed against rat tracheal epithelial cells transformed in vitro

International journal of cancer, 1984-01, Vol.33 (1), p.131-138

1984

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(6-Maleimidocaproyl)hydrazone of doxorubicin. A new derivative for the preparation of immunoconjugates of doxorubicin

Evaluation in vitro of adriamycin immunoconjugates synthesized using an acid-sensitive hydrazone linker

Effect of linker variation on the stability, potency, and efficacy of carcinoma-reactive BR64-doxorubicin immunoconjugates

Future approaches for treating hematologic disease

Enhancement of cell-mediated immunity in melanoma patients immunized with murine anti-idiotypic monoclonal antibodies (MELIMMUNE) that mimic the high molecular weight proteoglycan antigen

Antitumor activity of adriamycin (hydrazone-linked) immunoconjugates compared with free adriamycin and specificity of tumor cell killing

New hydrazone derivatives of Adriamycin and their immunoconjugates - a correlation between acid stability and cytotoxicity

Adriamycin(hydrazone)-antibody conjugates require internalization and intracellular acid hydrolysis for antitumor activity

Synthesis and antitumor activity of the immunoconjugate BR96-Dox

Antibody therapy of non-Hodgkin's B-cell lymphoma

Antigen-specific activity of carcinoma-reactive BR64-doxorubicin conjugates evaluated in vitro and in human tumor xenograft models

Cytotoxicity of chimeric (human-murine) monoclonal antibody BR96 IgG, F(ab')2, and Fab' conjugated to Pseudomonas exotoxin

Identification of functional domains in murine granulocyte-macrophage colony-stimulating factor using monoclonal antibodies to synthetic peptides

The structure of an antitumor C(H)2-domain-deleted humanized antibody

Granulocyte-macrophage colony-stimulating factor plays a role in the functional activity of mast cells

The Structure of an Antitumor C sub(H)2-domain-deleted Humanized Antibody

Combined use of AFM and X-ray diffraction to analyze crystals of an engineered, domain-deleted antibody

Modification of the Fc Region of a Primatized IgG Antibody to Human CD4 Retains Its Ability to Modulate CD4 Receptors but Does Not Deplete CD4+ T Cells in Chimpanzees

The induction of cytotoxic T cells and tumor regression by soluble antigen formulation

Determination of immunoreactivity of doxorubicin antibody immunoconjugates by a Ley competitive RIA

Induction of differentiation of human promyelocytic leukemia (HL-60) cells by teleocidin and phorbol-12-myristate-13-acetate

Tumor regression in mice following vaccination with human papillomavirus E7 recombinant protein in PROVAX

Direct binding of radioiodinated monoclonal antibody to tumor cells: significance of antibody purity and affinity for drug targeting or tumor imaging

Receptors for immune complexes on cells within a non-lymphoid murine tumor

Monoclonal antibodies directed against rat tracheal epithelial cells transformed in vitro

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