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The structural basis for specificity in lipoxygenase catalysis

Protein science, 2015-03, Vol.24 (3), p.298-309

2015

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The discovery and early structural studies of arachidonic acid

Journal of lipid research, 2016-07, Vol.57 (7), p.1126-1132

2016

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Mechanistic aspects of CYP74 allene oxide synthases and related cytochrome P450 enzymes

Phytochemistry (Oxford), 2009-09, Vol.70 (13), p.1522-1531

Brash, Alan R.

2009

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Recombinant PNPLA1 catalyzes the synthesis of acylceramides and acyl acids with selective incorporation of linoleic acid

Journal of lipid research, 2023-06, Vol.64 (6), p.100379-100379, Article 100379

2023

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The Structure of Human 5-Lipoxygenase

Science (American Association for the Advancement of Science), 2011-01, Vol.331 (6014), p.217-219

2011

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PNPLA1 has a crucial role in skin barrier function by directing acylceramide biosynthesis

Nature communications, 2017-03, Vol.8 (1), p.14609-14609, Article 14609

2017

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Routes to 4-Hydroxynonenal: Fundamental Issues in the Mechanisms of Lipid Peroxidation

The Journal of biological chemistry, 2008-06, Vol.283 (23), p.15539-15543

2008

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The importance of the lipoxygenase-hepoxilin pathway in the mammalian epidermal barrier

Biochimica et biophysica acta, 2014-03, Vol.1841 (3), p.401-408

2014

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Analysis of 12/15-lipoxygenase metabolism of EPA and DHA with special attention to authentication of docosatrienes

Journal of lipid research, 2021-01, Vol.62, p.100088-100088, Article 100088

2021

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Conversion of human 5‐lipoxygenase to a 15‐lipoxygenase by a point mutation to mimic phosphorylation at Serine‐663

The FASEB journal, 2012-08, Vol.26 (8), p.3222-3229

2012

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Failure to apply standard limit-of-detection or limit-of-quantitation criteria to specialized pro-resolving mediator analysis incorrectly characterizes their presence in biological samples

Nature communications, 2023-11, Vol.14 (1), p.7172-7172, Article 7172

2023

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Lipidomic and transcriptional analysis of the linoleoyl-omega-hydroxyceramide biosynthetic pathway in human psoriatic lesions

Journal of lipid research, 2021-01, Vol.62, p.100094-100094, Article 100094

2021

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Monolayer autoxidation of arachidonic acid to epoxyeicosatrienoic acids as a model of their potential formation in cell membranes

Journal of lipid research, 2022-01, Vol.63 (1), p.100159, Article 100159

2022

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Formation of 4-hydroxynonenal from cardiolipin oxidation: Intramolecular peroxyl radical addition and decomposition

Free radical biology & medicine, 2011-01, Vol.50 (1), p.166-178

2011

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Mutations in Recessive Congenital Ichthyoses Illuminate the Origin and Functions of the Corneocyte Lipid Envelope

Journal of investigative dermatology, 2019-04, Vol.139 (4), p.760-768

2019

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Catalytic activities of mammalian epoxide hydrolases with cis and trans fatty acid epoxides relevant to skin barrier function

Journal of lipid research, 2018-04, Vol.59 (4), p.684-695

2018

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Stereocontrolled synthesis of four isomeric linoleate triols of relevance to skin barrier formation and function

Tetrahedron letters, 2018-12, Vol.59 (52), p.4571-4573

2018

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A Single Active Site Residue Directs Oxygenation Stereospecificity in Lipoxygenases: Stereocontrol Is Linked to the Position of Oxygenation

Proceedings of the National Academy of Sciences - PNAS, 2004-11, Vol.101 (44), p.15579-15584

2004

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Challenging the evidence for hepoxilin A3 being a mediator of neutrophil epithelial transmigration

American journal of physiology. Lung cellular and molecular physiology, 2020-10, Vol.319 (4), p.L752-L753

Brash, Alan R

2020

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Fatty acids of Helicobacter pylori lipoproteins CagT and Lpp20

Microbiology spectrum, 2024-05, Vol.12 (5), p.e0047024-e0047024

2024

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The 1.85 Å Structure of an 8R-Lipoxygenase Suggests a General Model for Lipoxygenase Product Specificity

Biochemistry (Easton), 2009-08, Vol.48 (33), p.7906-7915

2009

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Lipoxygenase-catalyzed transformation of epoxy fatty acids to hydroxy-endoperoxides: a potential P450 and lipoxygenase interaction[S]

Journal of lipid research, 2014-12, Vol.55 (12), p.2587-2596

2014

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The hepoxilin connection in the epidermis

The FEBS journal, 2007-07, Vol.274 (14), p.3494-3502

2007

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A 49-kDa Mini-lipoxygenase from Anabaena sp. PCC 7120 Retains Catalytically Complete Functionality

The Journal of biological chemistry, 2008-02, Vol.283 (8), p.5138-5147

2008

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Catalase-Related Allene Oxide Synthase, on a Biosynthetic Route to Fatty Acid Cyclopentenones: Expression and Assay of the Enzyme and Preparation of the 8R-HPETE Substrate

Methods in enzymology, 2018, Vol.605, p.51-68

Brash, Alan R

2018

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The structural basis for specificity in lipoxygenase catalysis

The discovery and early structural studies of arachidonic acid

Mechanistic aspects of CYP74 allene oxide synthases and related cytochrome P450 enzymes

Recombinant PNPLA1 catalyzes the synthesis of acylceramides and acyl acids with selective incorporation of linoleic acid

The Structure of Human 5-Lipoxygenase

PNPLA1 has a crucial role in skin barrier function by directing acylceramide biosynthesis

Routes to 4-Hydroxynonenal: Fundamental Issues in the Mechanisms of Lipid Peroxidation

The importance of the lipoxygenase-hepoxilin pathway in the mammalian epidermal barrier

Analysis of 12/15-lipoxygenase metabolism of EPA and DHA with special attention to authentication of docosatrienes

Conversion of human 5‐lipoxygenase to a 15‐lipoxygenase by a point mutation to mimic phosphorylation at Serine‐663

Failure to apply standard limit-of-detection or limit-of-quantitation criteria to specialized pro-resolving mediator analysis incorrectly characterizes their presence in biological samples

Lipidomic and transcriptional analysis of the linoleoyl-omega-hydroxyceramide biosynthetic pathway in human psoriatic lesions

Monolayer autoxidation of arachidonic acid to epoxyeicosatrienoic acids as a model of their potential formation in cell membranes

Formation of 4-hydroxynonenal from cardiolipin oxidation: Intramolecular peroxyl radical addition and decomposition

Mutations in Recessive Congenital Ichthyoses Illuminate the Origin and Functions of the Corneocyte Lipid Envelope

Catalytic activities of mammalian epoxide hydrolases with cis and trans fatty acid epoxides relevant to skin barrier function

Stereocontrolled synthesis of four isomeric linoleate triols of relevance to skin barrier formation and function

A Single Active Site Residue Directs Oxygenation Stereospecificity in Lipoxygenases: Stereocontrol Is Linked to the Position of Oxygenation

Challenging the evidence for hepoxilin A3 being a mediator of neutrophil epithelial transmigration

Fatty acids of Helicobacter pylori lipoproteins CagT and Lpp20

The 1.85 Å Structure of an 8R-Lipoxygenase Suggests a General Model for Lipoxygenase Product Specificity

Lipoxygenase-catalyzed transformation of epoxy fatty acids to hydroxy-endoperoxides: a potential P450 and lipoxygenase interaction[S]

The hepoxilin connection in the epidermis

A 49-kDa Mini-lipoxygenase from Anabaena sp. PCC 7120 Retains Catalytically Complete Functionality

Catalase-Related Allene Oxide Synthase, on a Biosynthetic Route to Fatty Acid Cyclopentenones: Expression and Assay of the Enzyme and Preparation of the 8R-HPETE Substrate

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