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MHCEpitopeEnergy, a Flexible Rosetta-Based Biotherapeutic Deimmunization Platform

Journal of chemical information and modeling, 2021-05, Vol.61 (5), p.2368-2382

2021

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The Substrate-Bound Crystal Structure of a Baeyer–Villiger Monooxygenase Exhibits a Criegee-like Conformation

Journal of the American Chemical Society, 2012-05, Vol.134 (18), p.7788-7795

2012

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Computational Design of a Photocontrolled Cytosine Deaminase

Journal of the American Chemical Society, 2018-01, Vol.140 (1), p.14-17

2018

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A Bis(imidazole)-based cysteine labeling tool for metalloprotein assembly

Journal of inorganic biochemistry, 2023-07, Vol.244 (C), p.112206-112206, Article 112206

2023

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Crystal Structures of Cyclohexanone Monooxygenase Reveal Complex Domain Movements and a Sliding Cofactor

Journal of the American Chemical Society, 2009-07, Vol.131 (25), p.8848-8854

2009

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Chylomicronaemia--current diagnosis and future therapies

Nature reviews. Endocrinology, 2015-06, Vol.11 (6), p.352

2015

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Massively parallel, computationally guided design of a proenzyme

Proceedings of the National Academy of Sciences - PNAS, 2022-04, Vol.119 (15), p.e2116097119-e2116097119

2022

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The role of conformational flexibility in Baeyer-Villiger monooxygenase catalysis and structure

Biochimica et biophysica acta, 2016-12, Vol.1864 (12), p.1641-1648

2016

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Engineering carboxypeptidase G2 circular permutations for the design of an autoinhibited enzyme

Protein engineering, design and selection, 2017-04, Vol.30 (4), p.321-331

2017

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Distinct phenotype of hepatotoxicity associated with illicit use of anabolic androgenic steroids

Alimentary pharmacology & therapeutics, 2015-01, Vol.41 (1), p.116-125

2015

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Comprehensive characterization of ligand‐induced plasticity changes in a dimeric enzyme

The FEBS journal, 2016-08, Vol.283 (16), p.3029-3038

2016

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Combined hyperlipidemia: familial but not (usually) monogenic

Current opinion in lipidology, 2016-04, Vol.27 (2), p.131-140

2016

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Lactone-Bound Structures of Cyclohexanone Monooxygenase Provide Insight into the Stereochemistry of Catalysis

ACS chemical biology, 2014-12, Vol.9 (12), p.2843-2851

2014

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Fusion Economics: How Pragmatism is Changing the World

Brahm, L

1, 2014

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Genetic Confirmation Rate in Clinically Suspected Maturity-Onset Diabetes of the Young

Canadian journal of diabetes, 2016-12, Vol.40 (6), p.555-560

2016

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Incident Diabetes With Statins: Biology, Artifact, or Both?

Canadian journal of cardiology, 2015-08, Vol.31 (8), p.963-965

2015

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Multiple Conformers in Active Site of Human Dihydrofolate Reductase F31R/Q35E Double Mutant Suggest Structural Basis for Methotrexate Resistance

The Journal of biological chemistry, 2009-07, Vol.284 (30), p.20079-20089

2009

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158 A Randomized Controlled Trial of Emergency Department Ultrasound-Guided Reduction of Distal Radius Fractures

Annals of emergency medicine, 2011, Vol.58 (4), p.S230-S231

2011

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Structure-Based Design of Dimeric Bisbenzimidazole Inhibitors to an Emergent Trimethoprim-Resistant Type II Dihydrofolate Reductase Guides the Design of Monomeric Analogues

ACS omega, 2019-06, Vol.4 (6), p.10056-10069

2019

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Lomitapide for the treatment of hypertriglyceridemia

Expert opinion on investigational drugs, 2016-12, Vol.25 (12), p.1457-1463

2016

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Flux of selected body fluid constituents and benzylpenicillin in polyacrylamide hydrogel (PAAG)

Journal of tissue engineering and regenerative medicine, 2012-11, Vol.6 (10), p.793-802

2012

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863 CORRELATION OF IL28B POLYMORPHISM WITH DEGREE OF FIBROSIS: ANALYSIS OF TREATMENT-NAIVE AND TREATMENT-EXPERIENCED CAUCASIAN PATIENTS INFECTED WITH HCV GENOTYPE 1 IN THE GEN-C STUDY

Journal of hepatology, 2013-04, Vol.58, p.S354-S354

2013

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P1167 rs12979860 IL28B GENOTYPE IS ASSOCIATED WITH ADVANCED FIBROSIS IN HCV GENOTYPE 1-INFECTED EUROPEAN PATIENTS WITH CHRONIC HEPATITIS C: RESULTS FROM THE INTERNATIONAL GEN-C STUDY

Journal of hepatology, 2014-04, Vol.60 (1), p.S473-S473

2014

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Computational Design of a Photo-controlled Cytosine Deaminase

Journal of the American Chemical Society, 2017-12, Vol.140 (1), p.14-17

2017

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Liver transplantation today: situation in Chile

Transplantation proceedings, 1999-11, Vol.31 (7), p.3045-3045

Brahm, J

1999

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MHCEpitopeEnergy, a Flexible Rosetta-Based Biotherapeutic Deimmunization Platform

The Substrate-Bound Crystal Structure of a Baeyer–Villiger Monooxygenase Exhibits a Criegee-like Conformation

Computational Design of a Photocontrolled Cytosine Deaminase

A Bis(imidazole)-based cysteine labeling tool for metalloprotein assembly

Crystal Structures of Cyclohexanone Monooxygenase Reveal Complex Domain Movements and a Sliding Cofactor

Chylomicronaemia--current diagnosis and future therapies

Massively parallel, computationally guided design of a proenzyme

The role of conformational flexibility in Baeyer-Villiger monooxygenase catalysis and structure

Engineering carboxypeptidase G2 circular permutations for the design of an autoinhibited enzyme

Distinct phenotype of hepatotoxicity associated with illicit use of anabolic androgenic steroids

Comprehensive characterization of ligand‐induced plasticity changes in a dimeric enzyme

Combined hyperlipidemia: familial but not (usually) monogenic

Lactone-Bound Structures of Cyclohexanone Monooxygenase Provide Insight into the Stereochemistry of Catalysis

Fusion Economics: How Pragmatism is Changing the World

Genetic Confirmation Rate in Clinically Suspected Maturity-Onset Diabetes of the Young

Incident Diabetes With Statins: Biology, Artifact, or Both?

Multiple Conformers in Active Site of Human Dihydrofolate Reductase F31R/Q35E Double Mutant Suggest Structural Basis for Methotrexate Resistance

158 A Randomized Controlled Trial of Emergency Department Ultrasound-Guided Reduction of Distal Radius Fractures

Structure-Based Design of Dimeric Bisbenzimidazole Inhibitors to an Emergent Trimethoprim-Resistant Type II Dihydrofolate Reductase Guides the Design of Monomeric Analogues

Lomitapide for the treatment of hypertriglyceridemia

Flux of selected body fluid constituents and benzylpenicillin in polyacrylamide hydrogel (PAAG)

863 CORRELATION OF IL28B POLYMORPHISM WITH DEGREE OF FIBROSIS: ANALYSIS OF TREATMENT-NAIVE AND TREATMENT-EXPERIENCED CAUCASIAN PATIENTS INFECTED WITH HCV GENOTYPE 1 IN THE GEN-C STUDY

P1167 rs12979860 IL28B GENOTYPE IS ASSOCIATED WITH ADVANCED FIBROSIS IN HCV GENOTYPE 1-INFECTED EUROPEAN PATIENTS WITH CHRONIC HEPATITIS C: RESULTS FROM THE INTERNATIONAL GEN-C STUDY

Computational Design of a Photo-controlled Cytosine Deaminase

Liver transplantation today: situation in Chile

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