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Copper is an essential regulator of the autophagic kinases ULK1/2 to drive lung adenocarcinoma

Nature cell biology, 2020-04, Vol.22 (4), p.412

2020

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Activity-based ratiometric FRET probe reveals oncogene-driven changes in labile copper pools induced by altered glutathione metabolism

Proceedings of the National Academy of Sciences - PNAS, 2019-09, Vol.116 (37), p.18285-18294

2019

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Cuproptosis: Cellular and molecular mechanisms underlying copper-induced cell death

Molecular cell, 2022-05, Vol.82 (10), p.1786-1787

2022

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Evaluation of copper chaperone ATOX1 as prognostic biomarker in breast cancer

Breast cancer (Tokyo, Japan), 2020-05, Vol.27 (3), p.505-509

2020

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A Novel Role for Copper in Ras/Mitogen-Activated Protein Kinase Signaling

Molecular and Cellular Biology, 2012-04, Vol.32 (7), p.1284-1295

2012

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RALA and RALBP1 regulate mitochondrial fission at mitosis

Nature cell biology, 2011-09, Vol.13 (9), p.1108

2011

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Cuproptosis: Cellular and molecular mechanisms underlying copper-induced cell death

Molecular cell, 2022-05, Vol.82 (10), p.1786

2022

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Copper biology

Current biology, 2021-05, Vol.31 (9), p.R421-R427

2021

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YAP1 enhances NF-κB-dependent and independent effects on clock-mediated unfolded protein responses and autophagy in sarcoma

Cell death & disease, 2018-10, Vol.9 (11), p.1108-17, Article 1108

2018

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Understanding and drugging RAS: 40 years to break the tip of the iceberg

Disease models & mechanisms, 2022-02, Vol.15 (2)

2022

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Tracing copper utilization by kinase signal transduction pathways: Implications for cancer cell processes

The FASEB journal, 2022-05, Vol.36 (S1), p.n/a

Brady, Donita C.

2022

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Wnt5a signaling induced phosphorylation increases APT1 activity and promotes melanoma metastatic behavior

eLife, 2018-04, Vol.7

2018

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Direct anabolic metabolism of three-carbon propionate to a six-carbon metabolite occurs in vivo across tissues and species

Journal of lipid research, 2022-06, Vol.63 (6), p.100224-100224, Article 100224

2022

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Aurora-A Phosphorylates, Activates, and Relocalizes the Small GTPase RalA

Molecular and Cellular Biology, 2010-01, Vol.30 (2), p.508-523

2010

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Connecting copper and cancer: from transition metal signalling to metalloplasia

Nature reviews. Cancer, 2022-02, Vol.22 (2), p.102

2022

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Copper Chelation Inhibits BRAFV600E-Driven Melanomagenesis and Counters Resistance to BRAFV600E and MEK1/2 Inhibitors

Cancer research (Chicago, Ill.), 2017-11, Vol.77 (22), p.6240-6252

2017

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RASopathy mutations open new insights into the mechanism of BRAF activation

Molecular cell, 2022-11, Vol.82 (22), p.4192-4193

2022

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Copper is required for oncogenic BRAF signalling and tumorigenesis

Nature (London), 2014-05, Vol.509 (7501), p.492-496

2014

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Loss of p19Arf promotes fibroblast survival during leucine deprivation

Biology open, 2022-02, Vol.11 (2)

2022

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Copper Modulates the Catalytic Activity of Protein Kinase CK2

Frontiers in molecular biosciences, 2022-06, Vol.9, p.878652-878652

2022

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Altered copper homeostasis underlies sensitivity of hepatocellular carcinoma to copper chelation

Metallomics, 2020-12, Vol.12 (12), p.1995

2020

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Inhibition of BCL2 Family Members Increases the Efficacy of Copper Chelation in BRAFV600E-Driven Melanoma

Cancer research (Chicago, Ill.), 2020-04, Vol.80 (7), p.1387-1400

2020

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Regulation of Rnd3 localization and function by protein kinase C alpha-mediated phosphorylation

Biochemical journal, 2009-11, Vol.424 (1), p.153-161

2009

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The Race toward Equity: Increasing Racial Diversity in Cancer Research and Cancer Care

Cancer discovery, 2020-10, Vol.10 (10), p.1451-1454

2020

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The Transforming Rho Family GTPase Wrch-1 Disrupts Epithelial Cell Tight Junctions and Epithelial Morphogenesis

Molecular and Cellular Biology, 2009-02, Vol.29 (4), p.1035-1049

2009

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Copper is an essential regulator of the autophagic kinases ULK1/2 to drive lung adenocarcinoma

Activity-based ratiometric FRET probe reveals oncogene-driven changes in labile copper pools induced by altered glutathione metabolism

Cuproptosis: Cellular and molecular mechanisms underlying copper-induced cell death

Evaluation of copper chaperone ATOX1 as prognostic biomarker in breast cancer

A Novel Role for Copper in Ras/Mitogen-Activated Protein Kinase Signaling

RALA and RALBP1 regulate mitochondrial fission at mitosis

Cuproptosis: Cellular and molecular mechanisms underlying copper-induced cell death

Copper biology

YAP1 enhances NF-κB-dependent and independent effects on clock-mediated unfolded protein responses and autophagy in sarcoma

Understanding and drugging RAS: 40 years to break the tip of the iceberg

Tracing copper utilization by kinase signal transduction pathways: Implications for cancer cell processes

Wnt5a signaling induced phosphorylation increases APT1 activity and promotes melanoma metastatic behavior

Direct anabolic metabolism of three-carbon propionate to a six-carbon metabolite occurs in vivo across tissues and species

Aurora-A Phosphorylates, Activates, and Relocalizes the Small GTPase RalA

Connecting copper and cancer: from transition metal signalling to metalloplasia

Copper Chelation Inhibits BRAFV600E-Driven Melanomagenesis and Counters Resistance to BRAFV600E and MEK1/2 Inhibitors

RASopathy mutations open new insights into the mechanism of BRAF activation

Copper is required for oncogenic BRAF signalling and tumorigenesis

Loss of p19Arf promotes fibroblast survival during leucine deprivation

Copper Modulates the Catalytic Activity of Protein Kinase CK2

Altered copper homeostasis underlies sensitivity of hepatocellular carcinoma to copper chelation

Inhibition of BCL2 Family Members Increases the Efficacy of Copper Chelation in BRAFV600E-Driven Melanoma

Regulation of Rnd3 localization and function by protein kinase C alpha-mediated phosphorylation

The Race toward Equity: Increasing Racial Diversity in Cancer Research and Cancer Care

The Transforming Rho Family GTPase Wrch-1 Disrupts Epithelial Cell Tight Junctions and Epithelial Morphogenesis

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