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Simple vertebrate models for chemical genetics and drug discovery screens: Lessons from zebrafish and Xenopus

Developmental dynamics, 2009-06, Vol.238 (6), p.1287-1308

2009

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WT1 controls antagonistic FGF and BMP-pSMAD pathways in early renal progenitors

Nature communications, 2014-07, Vol.5 (1), p.4444-4444, Article 4444

2014

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Label-free determination of hemodynamic parameters in the microcirculaton with third harmonic generation microscopy

PloS one, 2014-06, Vol.9 (6), p.e99615-e99615

2014

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miR-31 Functions as a Negative Regulator of Lymphatic Vascular Lineage-Specific Differentiation In Vitro and Vascular Development In Vivo

Molecular and Cellular Biology, 2010-07, Vol.30 (14), p.3620-3634

2010

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Paracrine and autocrine mechanisms of apelin signaling govern embryonic and tumor angiogenesis

Developmental biology, 2007-05, Vol.305 (2), p.599-614

2007

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Functional genetic targeting of embryonic kidney progenitor cells ex vivo

Journal of the American Society of Nephrology, 2015-05, Vol.26 (5), p.1126-1137

2015

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Organization of the pronephric kidney revealed by large-scale gene expression mapping

Genome biology, 2008-01, Vol.9 (5), p.R84-R84

2008

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The prepattern transcription factor Irx3 directs nephron segment identity

Genes & development, 2007-09, Vol.21 (18), p.2358-2370

2007

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Chemical Screening and Toxicity Testing

Cold Spring Harbor protocols, 2023-04, Vol.2023 (4), p.pdb.top098251

Brändli, André W

2023

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Genome-wide gene expression profiling reveals renal genes regulated during metabolic acidosis

Physiological genomics, 2008-02, Vol.32 (3), p.322-334

2008

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An in vivo chemical library screen in Xenopus tadpoles reveals novel pathways involved in angiogenesis and lymphangiogenesis

Blood, 2009-07, Vol.114 (5), p.1110-1122

2009

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The FGFRL1 Receptor Is Shed from Cell Membranes, Binds Fibroblast Growth Factors (FGFs), and Antagonizes FGF Signaling in Xenopus Embryos

The Journal of biological chemistry, 2010-01, Vol.285 (3), p.2193-2202

2010

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A Role for All-Trans-Retinoic Acid in the Early Steps of Lymphatic Vasculature Development

Journal of vascular research, 2011-01, Vol.48 (3), p.236-251

2011

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Noncanonical Wnt-4 signaling and EAF2 are required for eye development in Xenopus laevis

The EMBO journal, 2005-03, Vol.24 (6), p.1181-1191

2005

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Engineering Xenopus embryos for phenotypic drug discovery screening

Advanced drug delivery reviews, 2014-04, Vol.69-70, p.225-246

2014

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Heat-shock mediated overexpression of HNF1β mutations has differential effects on gene expression in the Xenopus pronephric kidney

PloS one, 2012-03, Vol.7 (3), p.e33522

2012

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Screening of Chemical Libraries Using Xenopus Embryos and Tadpoles for Phenotypic Drug Discovery

Cold Spring Harbor protocols, 2023-04, Vol.2023 (4), p.pdb.prot098269

2023

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Functional characterization of two 20β-hydroxysteroid dehydrogenase type 2 homeologs from Xenopus laevis reveals multispecificity

The Journal of steroid biochemistry and molecular biology, 2021-06, Vol.210, p.105874, Article 105874

2021

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Gene expression analysis defines the proximal tubule as the compartment for endocytic receptor-mediated uptake in the Xenopus pronephric kidney

Pflügers Archiv, 2008-09, Vol.456 (6), p.1163-1176

2008

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Encoding chemistry

Nature chemical biology, 2009-07, Vol.5 (7), p.452-453

2009

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Essential Function of Wnt-4 for Tubulogenesis in the Xenopus Pronephric Kidney

Developmental biology, 2002-08, Vol.248 (1), p.13-28

2002

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Heat-Shock Mediated Overexpression of HNF1[beta] Mutations Has Differential Effects on Gene Expression in the Xenopus Pronephric Kidney

PloS one, 2012-03, Vol.7 (3), p.e33522

2012

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The receptor tyrosine kinase EphB4 and ephrin-B ligands restrict angiogenic growth of embryonic veins in Xenopus laevis

Development (Cambridge), 2000-01, Vol.127 (2), p.269-278

2000

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Xenopus Na,K-ATPase: primary sequence of the β2 subunit and in situ localization of α1, β1, and γ expression during pronephric kidney development

Differentiation (London), 2001, Vol.68 (2), p.115-125

2001

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Embryonic expression of Xenopus SGLT-1L, a novel member of the solute carrier family 5 (SLC5), is confined to tubules of the pronephric kidney

The International journal of developmental biology, 2002-01, Vol.46 (1), p.177

2002

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Simple vertebrate models for chemical genetics and drug discovery screens: Lessons from zebrafish and Xenopus

WT1 controls antagonistic FGF and BMP-pSMAD pathways in early renal progenitors

Label-free determination of hemodynamic parameters in the microcirculaton with third harmonic generation microscopy

miR-31 Functions as a Negative Regulator of Lymphatic Vascular Lineage-Specific Differentiation In Vitro and Vascular Development In Vivo

Paracrine and autocrine mechanisms of apelin signaling govern embryonic and tumor angiogenesis

Functional genetic targeting of embryonic kidney progenitor cells ex vivo

Organization of the pronephric kidney revealed by large-scale gene expression mapping

The prepattern transcription factor Irx3 directs nephron segment identity

Chemical Screening and Toxicity Testing

Genome-wide gene expression profiling reveals renal genes regulated during metabolic acidosis

An in vivo chemical library screen in Xenopus tadpoles reveals novel pathways involved in angiogenesis and lymphangiogenesis

The FGFRL1 Receptor Is Shed from Cell Membranes, Binds Fibroblast Growth Factors (FGFs), and Antagonizes FGF Signaling in Xenopus Embryos

A Role for All-Trans-Retinoic Acid in the Early Steps of Lymphatic Vasculature Development

Noncanonical Wnt-4 signaling and EAF2 are required for eye development in Xenopus laevis

Engineering Xenopus embryos for phenotypic drug discovery screening

Heat-shock mediated overexpression of HNF1β mutations has differential effects on gene expression in the Xenopus pronephric kidney

Screening of Chemical Libraries Using Xenopus Embryos and Tadpoles for Phenotypic Drug Discovery

Functional characterization of two 20β-hydroxysteroid dehydrogenase type 2 homeologs from Xenopus laevis reveals multispecificity

Gene expression analysis defines the proximal tubule as the compartment for endocytic receptor-mediated uptake in the Xenopus pronephric kidney

Encoding chemistry

Essential Function of Wnt-4 for Tubulogenesis in the Xenopus Pronephric Kidney

Heat-Shock Mediated Overexpression of HNF1[beta] Mutations Has Differential Effects on Gene Expression in the Xenopus Pronephric Kidney

The receptor tyrosine kinase EphB4 and ephrin-B ligands restrict angiogenic growth of embryonic veins in Xenopus laevis

Xenopus Na,K-ATPase: primary sequence of the β2 subunit and in situ localization of α1, β1, and γ expression during pronephric kidney development

Embryonic expression of Xenopus SGLT-1L, a novel member of the solute carrier family 5 (SLC5), is confined to tubules of the pronephric kidney

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