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In vitro metabolism of indiplon and an assessment of its drug interaction potential

Xenobiotica, 2007-07, Vol.37 (7), p.736-752

2007

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Neuroprotective Effects of the CRF1 Antagonist R121920 after Permanent Focal Ischemia in the Rat

Journal of cerebral blood flow and metabolism, 2001-10, Vol.21 (10), p.1208-1214

2001

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Design of 2,5-dimethyl-3-(6-dimethyl-4-methylpyridin-3-yl)-7-dipropylamino-pyrazolo[1,5-a] pyrimidine (NBI 30775/r121919) and structure-activity relationships of a series of potent and orally active corticotropin-releasing factor receptor antagonists

Journal of medicinal chemistry, 2004-09, Vol.47 (19), p.4787-4798

2004

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Potential error in the measurement of tissue to blood distribution coefficients in physiological pharmacokinetic modeling. Residual tissue blood. II. Distribution of phencyclidine in the rat

Drug metabolism and disposition, 1991-03, Vol.19 (2), p.486

1991

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Comparison of the pharmacokinetics of an ondansetron solution (8 mg) when administered intravenously, orally, to the colon, and to the rectum

Pharmaceutical research, 1994, Vol.11 (1), p.156-159

1994

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A novel on-line solid-phase extraction approach integrated with a monolithic column and tandem mass spectrometry for direct plasma analysis of multiple drugs and metabolites

Rapid communications in mass spectrometry, 2005-01, Vol.19 (22), p.3259-3268

2005

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3-[(2R)-Amino-2-phenylethyl]-1-(2,6-difluorobenzyl)-5-(2-fluoro-3-methoxyphenyl)- 6-methylpyrimidin-2,4-dione (NBI 42902) as a Potent and Orally Active Antagonist of the Human Gonadotropin-Releasing Hormone Receptor. Design, Synthesis, and in Vitro and in Vivo Characterization

Journal of medicinal chemistry, 2005-02, Vol.48 (4), p.1169-1178

2005

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Potent, Orally Active Corticotropin-Releasing Factor Receptor-1 Antagonists Containing a Tricyclic Pyrrolopyridine or Pyrazolopyridine Core

Journal of medicinal chemistry, 2005-06, Vol.48 (12), p.4100-4110

2005

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In vivo pharmacological characterization of indiplon, a novel pyrazolopyrimidine sedative-hypnotic

The Journal of pharmacology and experimental therapeutics, 2004-11, Vol.311 (2), p.547-559

2004

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Pharmacokinetics of ranitidine in morbidly obese women

DICP (Cincinnati, Ohio), 1990-11, Vol.24 (11), p.1040-1043

1990

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Rational Design, Synthesis, and Structure−Activity Relationships of Aryltriazoles as Novel Corticotropin-Releasing Factor-1 Receptor Antagonists

Journal of medicinal chemistry, 2005-03, Vol.48 (5), p.1540-1549

2005

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Oral Ondansetron Pharmacokinetics: The Effect of Chemotherapy

Journal of clinical pharmacology, 1994-07, Vol.34 (7), p.767-773

1994

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3-(2-Aminoalkyl)-1-(2,6-difluorobenzyl)-5- (2-fluoro-3-methoxyphenyl)-6-methyl- uracils as Orally Bioavailable Antagonists of the Human Gonadotropin Releasing Hormone Receptor

Journal of medicinal chemistry, 2004-07, Vol.47 (14), p.3483-3486

2004

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Ondansetron Absorption in Adults: Effect of Dosage Form, Food, and Antacids

Journal of pharmaceutical sciences, 1994-07, Vol.83 (7), p.1011-1013

1994

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Circadian variations in glutathione- S-transferase and glutathione peroxidase activities in the mouse

Toxicology letters, 1983-10, Vol.19 (1), p.23-27

1983

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Circadian rhythm in acetaminophen toxicity: Role of nonprotein sulfhydryls

Toxicology and applied pharmacology, 1983-12, Vol.71 (3), p.353-361

1983

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Distribution, excretion, and metabolism of butylbenzyl phthalate in the rat

Journal of toxicology and environmental health, 1986-01, Vol.17 (4), p.445-456

1986

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Design of 2,5-Dimethyl-3-(6-dimethyl-4-methylpyridin-3-yl)-7-dipropylaminopyrazolo[1,5-a]pyrimidine (NBI 30775/R121919) and Structure−Activity Relationships of a Series of Potent and Orally Active Corticotropin-Releasing Factor Receptor Antagonists

Journal of medicinal chemistry, 2004-09, Vol.47 (19), p.4787-4798

2004

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Factors influencing circadian rhythms in acetaminophen lethality

Pharmacology, 1984-01, Vol.29 (3), p.149-157

1984

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SPC‐100270, a protein kinase C inhibitor, reduced hypoxic injury due to reperfusion following orthotopic liver transplantation in the rat

Transplant international, 1994, Vol.7 (s1), p.167-170

1994

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Toxicity of the Protein Kinase C Inhibitor Safingol Administered Alone and in Combination with Chemotherapeutic Agents

Fundamental and applied toxicology, 1995-05, Vol.25 (2), p.201-217

1995

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Ondansetron absorption in adults : effects of dosage form, food, and antacids

Journal of pharmaceutical sciences, 1994, Vol.83 (7), p.1011-1013

1994

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A pharmacokinetic evaluation of five H1 antagonists after an oral and intravenous microdose to human subjects

British journal of clinical pharmacology, 2009-03, Vol.67 (3), p.288-298

2009

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A pharmacokinetic evaluation of five H 1 antagonists after an oral and intravenous microdose to human subjects

British journal of clinical pharmacology, 2009-03, Vol.67 (3), p.288-298

2009

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A pharmacokinetic evaluation of five H(1) antagonists after an oral and intravenous microdose to human subjects

British journal of clinical pharmacology, 2009-03, Vol.67 (3), p.288

2009

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In vitro metabolism of indiplon and an assessment of its drug interaction potential

Neuroprotective Effects of the CRF1 Antagonist R121920 after Permanent Focal Ischemia in the Rat

Design of 2,5-dimethyl-3-(6-dimethyl-4-methylpyridin-3-yl)-7-dipropylamino-pyrazolo[1,5-a] pyrimidine (NBI 30775/r121919) and structure-activity relationships of a series of potent and orally active corticotropin-releasing factor receptor antagonists

Potential error in the measurement of tissue to blood distribution coefficients in physiological pharmacokinetic modeling. Residual tissue blood. II. Distribution of phencyclidine in the rat

Comparison of the pharmacokinetics of an ondansetron solution (8 mg) when administered intravenously, orally, to the colon, and to the rectum

A novel on-line solid-phase extraction approach integrated with a monolithic column and tandem mass spectrometry for direct plasma analysis of multiple drugs and metabolites

3-[(2R)-Amino-2-phenylethyl]-1-(2,6-difluorobenzyl)-5-(2-fluoro-3-methoxyphenyl)- 6-methylpyrimidin-2,4-dione (NBI 42902) as a Potent and Orally Active Antagonist of the Human Gonadotropin-Releasing Hormone Receptor. Design, Synthesis, and in Vitro and in Vivo Characterization

Potent, Orally Active Corticotropin-Releasing Factor Receptor-1 Antagonists Containing a Tricyclic Pyrrolopyridine or Pyrazolopyridine Core

In vivo pharmacological characterization of indiplon, a novel pyrazolopyrimidine sedative-hypnotic

Pharmacokinetics of ranitidine in morbidly obese women

Rational Design, Synthesis, and Structure−Activity Relationships of Aryltriazoles as Novel Corticotropin-Releasing Factor-1 Receptor Antagonists

Oral Ondansetron Pharmacokinetics: The Effect of Chemotherapy

3-(2-Aminoalkyl)-1-(2,6-difluorobenzyl)-5- (2-fluoro-3-methoxyphenyl)-6-methyl- uracils as Orally Bioavailable Antagonists of the Human Gonadotropin Releasing Hormone Receptor

Ondansetron Absorption in Adults: Effect of Dosage Form, Food, and Antacids

Circadian variations in glutathione- S-transferase and glutathione peroxidase activities in the mouse

Circadian rhythm in acetaminophen toxicity: Role of nonprotein sulfhydryls

Distribution, excretion, and metabolism of butylbenzyl phthalate in the rat

Design of 2,5-Dimethyl-3-(6-dimethyl-4-methylpyridin-3-yl)-7-dipropylaminopyrazolo[1,5-a]pyrimidine (NBI 30775/R121919) and Structure−Activity Relationships of a Series of Potent and Orally Active Corticotropin-Releasing Factor Receptor Antagonists

Factors influencing circadian rhythms in acetaminophen lethality

SPC‐100270, a protein kinase C inhibitor, reduced hypoxic injury due to reperfusion following orthotopic liver transplantation in the rat

Toxicity of the Protein Kinase C Inhibitor Safingol Administered Alone and in Combination with Chemotherapeutic Agents

Ondansetron absorption in adults : effects of dosage form, food, and antacids

A pharmacokinetic evaluation of five H1 antagonists after an oral and intravenous microdose to human subjects

A pharmacokinetic evaluation of five H 1 antagonists after an oral and intravenous microdose to human subjects

A pharmacokinetic evaluation of five H(1) antagonists after an oral and intravenous microdose to human subjects

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