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International Union of Pharmacology LVIII: update on the P2Y G protein-coupled nucleotide receptors: from molecular mechanisms and pathophysiology to therapy

Pharmacological reviews, 2006-09, Vol.58 (3), p.281-341

2006

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P2Y₂ receptor activation decreases blood pressure and increases renal Na⁺ excretion

American journal of physiology. Regulatory, integrative and comparative physiology, 2011-08, Vol.301 (2), p.R510-R518

2011

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Characterization of the UDP-glucose receptor (re-named here the P2Y 14 receptor) adds diversity to the P2Y receptor family

Trends in pharmacological sciences (Regular ed.), 2003-02, Vol.24 (2), p.52-55

2003

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Ocular surface distribution and pharmacokinetics of a novel ophthalmic 1% azithromycin formulation

Journal of ocular pharmacology and therapeutics, 2009-10, Vol.25 (5), p.433-440

2009

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A Randomized, Controlled Comparison of NCX 470 (0.021%, 0.042%, and 0.065%) and Latanoprost 0.005% in Patients With Open-angle Glaucoma or Ocular Hypertension: The Dolomites Study

Journal of glaucoma, 2022-06, Vol.31 (6), p.382-391

2022

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Human P2Y1 Receptor: Molecular Modeling and Site-Directed Mutagenesis as Tools To Identify Agonist and Antagonist Recognition Sites

Journal of medicinal chemistry, 1998-04, Vol.41 (9), p.1456-1466

1998

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Functional expression of a cDNA encoding a human ecto‐ATPase

British journal of pharmacology, 1999-09, Vol.128 (2), p.396-402

1999

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Lipophilic Modifications to Dinucleoside Polyphosphates and Nucleotides that Confer Antagonist Properties at the Platelet P2Y12 Receptor

Journal of medicinal chemistry, 2008-02, Vol.51 (4), p.1007-1025

2008

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Regulation of P2Y1 Receptor-Mediated Signaling by the Ectonucleoside Triphosphate Diphosphohydrolase Isozymes NTPDase1 and NTPDase2

Molecular pharmacology, 2005-01, Vol.67 (1), p.114-122

2005

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Induction of novel agonist selectivity for the ADP-activated P2Y1 receptor versus the ADP-activated P2Y12 and P2Y13 receptors by conformational constraint of an ADP analog

The Journal of pharmacology and experimental therapeutics, 2004-12, Vol.311 (3), p.1038

2004

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Methanocarba Modification of Uracil and Adenine Nucleotides: High Potency of Northern Ring Conformation at P2Y1, P2Y2, P2Y4, and P2Y11 but Not P2Y6 Receptors

Journal of medicinal chemistry, 2002-01, Vol.45 (1), p.208-218

2002

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Purification and Functional Reconstitution of the Human P2Y12 Receptor

Molecular pharmacology, 2003-11, Vol.64 (5), p.1210-1216

2003

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Deoxyadenosine Bisphosphate Derivatives as Potent Antagonists at P2Y1 Receptors

Journal of medicinal chemistry, 1998-01, Vol.41 (2), p.183-190

1998

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Structure-activity relationships of dinucleotides: Potent and selective agonists of P2Y receptors

Purinergic signalling, 2005-06, Vol.1 (2), p.183-191, Article 183

2005

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Acyclic and Cyclopropyl Analogues of Adenosine Bisphosphate Antagonists of the P2Y1 Receptor: Structure−Activity Relationships and Receptor Docking

Journal of medicinal chemistry, 2001-09, Vol.44 (19), p.3092-3108

2001

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Synthesis, Biological Activity, and Molecular Modeling of Ribose-Modified Deoxyadenosine Bisphosphate Analogues as P2Y1 Receptor Ligands

Journal of medicinal chemistry, 2000-03, Vol.43 (5), p.829-842

2000

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Structure−Activity Relationships of Pyridoxal Phosphate Derivatives as Potent and Selective Antagonists of P2X1 Receptors

Journal of medicinal chemistry, 2001-02, Vol.44 (3), p.340-349

2001

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Adenine Nucleotide Analogues Locked in a Northern Methanocarba Conformation: Enhanced Stability and Potency as P2Y1 Receptor Agonists

Journal of medicinal chemistry, 2002-05, Vol.45 (10), p.2090-2100

2002

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Transformation by a nucleotide-activated P2Y receptor is mediated by activation of Gαi, Gαq and Rho-dependent signaling pathways

Journal of molecular signaling, 2010-07, Vol.5, p.11-11

2010

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Adenosine analogues as inhibitors of P2Y12 receptor mediated platelet aggregation

Bioorganic & medicinal chemistry letters, 2008-03, Vol.18 (6), p.2167-2171

2008

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Differential effects of P2‐purinoceptor antagonists on phospholipase C‐ and adenylyl cyclase‐coupled P2Y‐purinoceptors

British journal of pharmacology, 1994-10, Vol.113 (2), p.614-620

1994

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Structure−Activity Relationships of Bisphosphate Nucleotide Derivatives as P2Y1 Receptor Antagonists and Partial Agonists

Journal of medicinal chemistry, 1999-05, Vol.42 (9), p.1625-1638

1999

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A Pyridoxine Cyclic Phosphate and Its 6-Azoaryl Derivative Selectively Potentiate and Antagonize Activation of P2X1 Receptors

Journal of medicinal chemistry, 1998-06, Vol.41 (13), p.2201-2206

1998

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Molecular Recognition of Modified Adenine Nucleotides by the P2Y1-Receptor. 1. A Synthetic, Biochemical, and NMR Approach

Journal of medicinal chemistry, 1999-12, Vol.42 (26), p.5325-5337

1999

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A Fusion Protein of the Human P2Y1 Receptor and NTPDase1 Exhibits Functional Activities of the Native Receptor and Ectoenzyme and Reduced Signaling Responses to Endogenously Released Nucleotides

Molecular pharmacology, 2002-09, Vol.62 (3), p.521

2002

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International Union of Pharmacology LVIII: update on the P2Y G protein-coupled nucleotide receptors: from molecular mechanisms and pathophysiology to therapy

P2Y₂ receptor activation decreases blood pressure and increases renal Na⁺ excretion

Characterization of the UDP-glucose receptor (re-named here the P2Y 14 receptor) adds diversity to the P2Y receptor family

Ocular surface distribution and pharmacokinetics of a novel ophthalmic 1% azithromycin formulation

A Randomized, Controlled Comparison of NCX 470 (0.021%, 0.042%, and 0.065%) and Latanoprost 0.005% in Patients With Open-angle Glaucoma or Ocular Hypertension: The Dolomites Study

Human P2Y1 Receptor: Molecular Modeling and Site-Directed Mutagenesis as Tools To Identify Agonist and Antagonist Recognition Sites

Functional expression of a cDNA encoding a human ecto‐ATPase

Lipophilic Modifications to Dinucleoside Polyphosphates and Nucleotides that Confer Antagonist Properties at the Platelet P2Y12 Receptor

Regulation of P2Y1 Receptor-Mediated Signaling by the Ectonucleoside Triphosphate Diphosphohydrolase Isozymes NTPDase1 and NTPDase2

Induction of novel agonist selectivity for the ADP-activated P2Y1 receptor versus the ADP-activated P2Y12 and P2Y13 receptors by conformational constraint of an ADP analog

Methanocarba Modification of Uracil and Adenine Nucleotides: High Potency of Northern Ring Conformation at P2Y1, P2Y2, P2Y4, and P2Y11 but Not P2Y6 Receptors

Purification and Functional Reconstitution of the Human P2Y12 Receptor

Deoxyadenosine Bisphosphate Derivatives as Potent Antagonists at P2Y1 Receptors

Structure-activity relationships of dinucleotides: Potent and selective agonists of P2Y receptors

Acyclic and Cyclopropyl Analogues of Adenosine Bisphosphate Antagonists of the P2Y1 Receptor: Structure−Activity Relationships and Receptor Docking

Synthesis, Biological Activity, and Molecular Modeling of Ribose-Modified Deoxyadenosine Bisphosphate Analogues as P2Y1 Receptor Ligands

Structure−Activity Relationships of Pyridoxal Phosphate Derivatives as Potent and Selective Antagonists of P2X1 Receptors

Adenine Nucleotide Analogues Locked in a Northern Methanocarba Conformation: Enhanced Stability and Potency as P2Y1 Receptor Agonists

Transformation by a nucleotide-activated P2Y receptor is mediated by activation of Gαi, Gαq and Rho-dependent signaling pathways

Adenosine analogues as inhibitors of P2Y12 receptor mediated platelet aggregation

Differential effects of P2‐purinoceptor antagonists on phospholipase C‐ and adenylyl cyclase‐coupled P2Y‐purinoceptors

Structure−Activity Relationships of Bisphosphate Nucleotide Derivatives as P2Y1 Receptor Antagonists and Partial Agonists

A Pyridoxine Cyclic Phosphate and Its 6-Azoaryl Derivative Selectively Potentiate and Antagonize Activation of P2X1 Receptors

Molecular Recognition of Modified Adenine Nucleotides by the P2Y1-Receptor. 1. A Synthetic, Biochemical, and NMR Approach

A Fusion Protein of the Human P2Y1 Receptor and NTPDase1 Exhibits Functional Activities of the Native Receptor and Ectoenzyme and Reduced Signaling Responses to Endogenously Released Nucleotides

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